|   |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
|
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
|
|
. | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
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|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
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| . |
. |
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| . |
. |
. |
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| Query Sequence |   |
V | R | E | G | S | K | R | V | F | N | M | T | P | Y | K | V | Q | I | M | G | G | I | A | I | H | K | G | D | . |
. |
I | A | E | M | R | T | G | E | G | K | T | L | T | A | T | M | P | T | Y | . |
. |
. |
L | N | A | L | A | G | R | G | V | H | V | I | T | V | N | E | Y | L | S | S | V | Q | S | E | E | M | A | E |
| Query Conservation |   |
|
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|   |   |
|   |
|
|   |   |
|   |   |
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|   |   |   |
|   |   |
|   | . | . |
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|   |
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|   |   |
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|   | . | . | . |
|   |
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|   |
|   |   |
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|   |
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|   |
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|   |
|   |   |   |   |
| Alig confidence |   |
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| . | . |
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| . | . | . |
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| Template Conservation |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |
|
|
|   |
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|
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
L | L | M | G | I | F | E | A | G | F | E | K | P | S | P | I | Q | E | E | A | I | P | V | A | I | T | G | R | D | I | L | A | R | A | K | N | G | T | G | K | T | A | A | F | V | I | P | T | L | E | K | V | K | P | K | L | N | K | I | Q | A | L | I | M | V | P | T | R | E | L | A | L | Q | T | S | Q | V | V | R | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
| S |
|
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
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|
|  |  |  |  |  |  |  |  |  |  |  |
|
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|  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
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|   |   |
57 | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
|   |
|   |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
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|
|
|  |
| Query SS confidence |   |
|
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| . |
. |
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| Query Sequence |   |
L | Y | N | F | L | G | L | T | V | G | L | N | L | N | S | K | T | T | E | E | K | R | E | A | Y | A | Q | D | . |
. |
I | T | Y | S | T | N | N | E | L | G | F | D | Y | L | R | D | N | M | V | N | Y | S | E | D | R | V | M | R | P | L | H | F | A | I | I | D | E | V | D | S | I | L | I | D | E | A | R | T | P | L |
| Query Conservation |   |
|
|   |   |
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
| . | . |
|   |
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|   |   |
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|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
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| Alig confidence |   |
|
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| . | . |
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| . |
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|
| . | . | . | . | . | . |
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|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
| Template Sequence |   |
L | G | K | H | C | G | I | S | C | M | V | T | T | G | G | T | N | L | R | D | D | I | L | R | L | N | E | T | V | H | I | L | V | G | T | P | G | R | V | . |
L | D | L | A | S | R | K | V | A | D | . |
. |
. |
. |
. |
. |
L | S | D | C | S | L | F | I | M | D | E | A | D | K | M | L | . |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 | T | T | T | T | T |
|
|  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  | T | T | S |
|
| S |  |  |  |  |
|  |  |  |  | . |  |  |  |  |  | T | T |
| S |
| . | . | . | . | . | . |
| T | T |
|
|  |  |  |  |  | S |  |  |  |  | S | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
| . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
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|
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|   |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
. | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
|
|
|
|
|
|
|   |
|   |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
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|  |  |  |
|
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|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
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|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
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|
| Query Sequence |   |
I | I | S | G | E | A | E | K | S | T | S | L | Y | T | Q | A | N | V | F | A | K | M | L | K | Q | D | E | D | Y | K | Y | D | E | K | T | K | A | V | H | L | T | E | Q | G | A | D | K | A | E | R | M | F | K | V | E | N | L | Y | D | V | Q | N | V | D | V | I | S | H | I | N | T | A | L | R | A | H | V | T | L | Q |
| Query Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . |
|
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
S | R | D | F | K | T | I | I | E | Q | I | L | S | F | L | P | P | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
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|   |   |
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202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
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|   |
|   |   |
308 | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
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|  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
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| Query Sequence |   |
R | D | V | D | Y | M | V | V | D | G | E | V | L | I | V | D | Q | F | T | G | R | T | M | P | G | R | R | F | S | E | G | L | H | Q | A | I | E | A | K | E | G | V | Q | I | Q | N | E | S | K | T | M | A | S | I | T | F | Q | N | Y | F | R | M | Y | N | K | L | A | G | M | T | G | T | A | K | T | E | E | E | E | F |
| Query Conservation |   |
  |
|   |
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|   |   |   |   |
|   |
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|   |
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|   |   |   |
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| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
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H | Q | S | L | L | F | S | A | T | F | P | L | T | V | K | E | F |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  | S |
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| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template SS confidence |   |
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220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
|   |
|   |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
R | N | I | Y | N | M | T | V | T | Q | I | P | T | N | K | P | V | Q | R | N | D | K | S | D | L | I | Y | I | S | Q | K | G | K | F | D | A | V | V | E | D | V | V | E | K | H | K | A | G | Q | P | V | L | L | G | T | V | A | V | E | T | S | E | Y | I | S | N | L | L | K | K | R | G | I | R | H | D | V | L | N | A |
| Query Conservation |   |
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| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | V | K | H | L | H | K | P | Y | E | I | N | L | M | E | E | L | T | L | K | G | I | T | Q | Y | Y | A | F | V | E | E | R | Q | K | L | H | C | L | N | T | L | F | S | K | L | Q | I | N | Q | . |
A | I | I | F | C | N | S | T | N | R | V | E | L | L | A | K | K | I | T | D | L | G | Y | S | C | Y | Y | S | H | A |
| Template Known Secondary structure |   |
 |  |  |  |
| S | S |
|  |  |  | S |
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| S | S |
| B |
| T | T |  |  |  |  |  |  |  |
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| G | G | G |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S |  | . |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T |
| Template Predicted Secondary structure |   |
 |  |  |
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|  | . |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
|   |
|   |   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | |
|
. | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | |
. | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . |
| Predicted Secondary structure |   |
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|  |  |  |  |  |  |  |  |  |
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| . | . |
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| Query SS confidence |   |
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| Query Sequence |   |
K | N | H | E | R | E | A | E | I | V | A | G | A | G | Q | K | G | . |
. |
A | V | T | I | A | T | N | M | A | G | R | G | T | D | I | K | L | G | E | G | V | E | E | L | G | G | L | . |
A | V | I | G | T | E | R | H | E | S | R | R | I | D | D | Q | L | R | G | R | S | G | R | Q | G | D | K | G | D | S | R | F | Y |
| Query Conservation |   |
|   |   |   |   |
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| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
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|   |   |   |   |   |
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| . | . | . | . | . | . | . | . | . |   |
|   |   |
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|   |   |
| Template Sequence |   |
R | M | K | Q | Q | E | R | N | K | V | F | H | E | F | R | Q | G | K | V | R | T | L | V | C | S | D | L | L | T | R | G | I | D | I | Q | . |
. |
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A | V | N | V | V | I | N | F | D | F | P | K | T | A | E | T | Y | L | H | R | I | G | R | S | G | R | F | G | H | L | G | L | A | I | N | L |
| Template Known Secondary structure |   |
T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |  |  |  |  | S | S |
| S | S | S | S |
|
|
| T | . | . | . | . | . | . | . | . | . | T |  |  |  |  |  |  | S | S |
|
| S | S |  |  |  |  |  |  |  |  |
| B | S | S |
| T | T |
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|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
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|  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
316 | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
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. | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
|   |
|   |   |
545 | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 |
| Predicted Secondary structure |   |
 |  |
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|  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
L | S | L | Q | D | E | L | M | I | R | F | G | S | E | R | L | Q | K | M | M | S | R | L | G | L | D |
| Query Conservation |   |
|
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|   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
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| . | . | . | . | . | . | . |
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| Template Conservation |   |
  |   |   |   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
| Template Sequence |   |
I | N | W | N | D | . |
. |
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. |
R | F | N | L | Y | K | I | E | Q | E | L | G | T | E |
| Template Known Secondary structure |   |
 |
| G | G | G | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| Template Predicted Secondary structure |   |
 |
|  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
387 | . | . | 390 | . | |
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. | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
|   |