|   |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
|
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | R | L | P | F | E | L | T | E | A | Q | K | S | S | V | N | E | I | F | R | . |
. |
. |
D | L | K | A | P | I | R | M | H | R | L | L | Q | G | D | V | G | S | G | K | T | V | V | A | A | I | C | M | Y | A | L | K | T | A | G | . |
. |
. |
. |
. |
. |
. |
Y | Q | S | A | L | M | V | P | T | E | I | L | A | E | Q |
| Query Conservation |   |
  |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |
|   |   | . | . | . |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |
| . | . | . | . | . | . | . |   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
|   |
|   |   |   |
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
| . |   |
|
|   |   |
|
| Template Sequence |   |
P | V | L | S | K | V | L | R | P | H | Q | R | E | G | V | K | F | L | W | D | C | V | T | G | R | R | I | E | N | S | Y | G | C | I | M | A | D | E | M | G | L | G | K | T | L | Q | C | I | T | L | I | W | T | L | L | K | Q | S | P | D | C | K | P | E | I | D | K | V | I | V | V | S | P | . |
S | S | L | V | R | N |
| Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | T | T |
|
|  |  |  |  |
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S | S |
| S |
| S |
|  |  |  |  |  |
| . |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| . |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
. | . | . | . | . | . |
|   |
|   |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
|
|
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
|
|
. | . | . | . | . | 390 | . | . | . | . | . | . | . | |
|
. | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|  |  |  |  |
|
|  |  |  |
| . | . |
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
| Query Sequence |   |
H | A | E | S | L | M | A | L | F | G | D | S | M | N | V | A | L | L | T | G | S | V | K | G | K | K | R | K | I | L | L | E | Q | L | E | N | G | T | I | . |
. |
. |
. |
D | C | L | I | G | T | H | A | L | I | Q | D | D | V | I | F | H | . |
. |
. |
N | V | G | L | V | I | T | D | E | Q | H | R | F | . |
. |
G | V |
| Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   | . | . | . | . |   |
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   | . | . | . |   |
|   |
|
|
|
|
|
|
|
|   |
| . | . |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| Template Conservation |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|
|
|   |   |
| Template Sequence |   |
W | Y | N | E | V | G | K | W | L | G | G | R | V | Q | P | V | A | I | D | G | G | S | K | D | E | I | D | S | K | L | V | N | F | I | S | Q | Q | G | M | R | I | P | T | P | I | L | I | I | S | Y | E | T | F | R | L | H | A | E | V | L | H | K | G | K | V | G | L | V | I | C | D | E | G | H | R | L | K | N | S | D |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | G | G | G |
|
|  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | T | S |
|
|
|  |  |  |  | T | T | G | G | G |
|
| T | T |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
| Query Sequence |   |
N | Q | R | Q | L | L | R | E | K | G | A | M | T | N | V | L | F | M | T | A | T | P | I | P | R | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | A |
| Query Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
N | Q | T | Y | L | A | L | N | S | M | N | A | Q | R | R | V | L | I | S | G | T | P | I | Q | N | D | L | L | E | Y | F | S | L | V | H | F | V | N | S | G | I | L | G | T | A | Q | E | F | K | K | R | F | E | I | P | I | L | K | G | R | D | A | D | A | S | D | K | D | R | A | A | G | E | Q | K | L | Q | E | L | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |
| S | S |
| S | G | G | G | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  | S | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
428 | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
I | S | V | F | G | E | M | D | V | S | S | I | K | Q | L | P | K | G | R | K | P | I | I | T | T | W | A | K | H | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |
| Template Sequence |   |
S | I | V | N | R | C | L | I | R | R | T | S | D | I | L | S | K | Y | L | P | V | K | I | E | Q | V | V | C | C | N | L | T | P | L | Q | K | E | L | Y | K | L | F | L | K | Q | A | K | P | V | E | S | L | Q | T | G | K | I | S | V | S | S | L | S | S | I | T | S | L | K | K | L | C | N | H | P | A | L | I | Y | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
| G | G | G | G | G | G | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | S | S |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
458 | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
. | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | Y | D | K | V | L | M | Q | M | T | S | E | L | . |
K | K | G | R | Q | A | Y | V | I | C | P | L | I | E | S | S | E | H | L | E | D | V | Q | N | V | V | A | L | Y | E | S | L | Q | Q | Y |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |   |
| . |   |   |   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   | . |
| Template Sequence |   |
K | C | L | T | G | E | E | G | F | D | G | A | L | D | L | F | P | Q | N | Y | S | T | K | A | V | E | P | Q | L | S | G | K | M | L | V | L | D | Y | I | L | A | M | T | R | T | T | T | S | D | K | V | V | L | V | S | N | Y | T | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
T | L | D | L | F | E | K | L | C | R | N | . |
| Template Known Secondary structure |   |
 |  |  |  | T |
| T | T |
| T | T | G | G | G | T | S |
| S | S |
|
| S | S | S |
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | S |
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 520 | . | . | . | . | . | . | . | . | . | |
|   |
|   |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | |
|
|
. | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | G | V | S | R | V | G | L | L | H | G | K | L | S | A | D | E | K | D | E | V | M | Q | K | F | S | N | H | E | . |
. |
. |
I | N | V | L | V | S | T | T | V | V | E | V | G | V | N | V | P | N | A | T | F | M | M | I | Y | D | A | D | R | F | G | L | S | T | L | H | Q | L | R | G | R | V | G | R | S | D | Q | Q |
| Query Conservation |   |
  |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |
|   | . | . | . |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|   |
|   |   |
|
|
|   |   |
|   |
|
|   |   |
|   |
|
|
|
|   |
|
|
|
|
|   |
|   |   |
| Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |
|
|   |   |
|   |   | . |
|
|
|   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|   |
| Template Sequence |   |
. |
R | R | Y | L | Y | V | R | L | D | G | T | M | S | I | K | K | R | A | K | I | V | E | R | F | N | N | P | S | S | P | E | F | I | F | M | L | S | S | K | A | G | G | C | G | L | N | L | I | G | A | N | R | L | V | M | F | D | P | D | . |
W | N | P | A | N | D | E | Q | A | M | A | R | V | W | R | D | G | Q | K |
| Template Known Secondary structure |   |
. |  | T |
|
|  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
|
|
|  |  |  |  |  | G | G | G | S |
| T | T |
|
|
| T | T |  |  |  |  |  |  |
| S |
|
| . | S | S |  |  |  |  |  |  |  |  | T | T | S | S | S | T | T |
|
|
| Template Predicted Secondary structure |   |
. |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | |
. | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . |
|   |
|   |   |
583 | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | Y | C | V | L | I | A | S | P | K | T | E | T | G | I | E | R | M | T | I | M | T | Q |
| Query Conservation |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|
|   |
|   |   |   |
|
|
|
|
|   |
|   |   |   |   |   |
| Template Sequence |   |
K | T | C | Y | I | Y | R | L | L | S | T | G | T | I | E | E | K | I | L | Q | R | Q | A |
| Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
608 | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 |
|   |