|   |   |
1 | . | . | |
|
|
. | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
| Predicted Secondary structure |   |
|
|  | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | P | K | . |
. |
. |
I | V | V | V | G | A | V | A | G | G | A | T | C | A | S | Q | I | R | R | L | D | K | E | S | D | I | I | I | F | E | K | D | R | D | M | S | F | . |
. |
. |
. |
A | N | C | A | L | P | Y | V | I | G | E | V | V | E | D | R | R | Y | A | L | A | Y | T | P | E | K | F | Y | D | R | K | Q | I |
| Query Conservation |   |
|
|
| . | . | . |
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|   | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |
|
|   |   | . | . |
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | K | R | H | Y | E | A | V | V | I | G | G | G | I | I | G | S | A | I | A | Y | Y | L | A | K | E | . |
. |
N | K | N | T | A | L | F | E | S | G | T | M | G | G | R | T | T | S | A | A | A | G | M | L | G | A | H | A | E | C | E | E | R | D | A | F | F | D | F | A | M | H | S | Q | R | L | Y | K | G | L | G | E |
| Template Known Secondary structure |   |
|
| S |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|
|  |  |  |  |
| S | S | S | T | T | T | T |  |  |  |  |
|
|
| B |
|
| G | G | G | S |
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
|   |
|   |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | V | K | T | Y | H | E | V | I | A | I | N | D | E | R | Q | T | V | S | V | L | N | R | K | T | N | E | Q | F | E | E | S | Y | D | K | L | I | L | S | P | G | A | S | A | N | S | L | G | F | E | S | D | I | T | F | T | L | R | N | L | E | D | T | D | A | I | D | Q | F | I | K | A | N | Q | V | D | K | V | L | V |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | A | L | S | G | V | D | I | R | Q | H | N | G | G | M | F | K | L | A | F | S | E | E | D | V | L | Q | L | R | Q | M | D | D | L | D | S | V | S | W |
| Template Known Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
| B |
|
|
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  | T | T | T | T | S | T | T |  |  |  |
| Template Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
79 | 80 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
220 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . |  |  |  |  |
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | G | A | G | Y | V | S | L | E | V | L | E | N | L | N | E | R | G | L | H | P | T | L | I | H | R | S | D | K | I | N | K | L | M | D | A | D | M | N | Q | P | I | L | D | E | L | D | K | R | E | I | P | Y | R | L | N | E | E | I | N | A | I | N | G | N | E | . |
. |
. |
. |
I | T | F | K | S | G | K | V | E | H |
| Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . |
|
|
| Template Conservation |   |
  |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|   | . |
|   |
| Template Sequence |   |
Y | S | K | E | . |
. |
. |
. |
E | V | L | E | K | E | P | Y | A | S | G | D | I | F | G | A | S | F | I | Q | D | D | V | H | V | E | P | Y | F | V | C | K | A | Y | V | K | A | A | K | M | L | G | A | E | I | F | E | H | T | P | V | L | H | V | E | R | D | G | E | A | L | F | I | K | T | P | S | G | D | . |
V | W |
| Template Known Secondary structure |   |
 |  |  |  | . | . | . | . |  |  |  |  |  |
| T | T | S |
| T | T |
|
|  |  |  |  |  | T | T |
|
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  | T | T |
|
|
|
|  |  |  |
| S | S | S | S |  |  |  |  |  | T | T |  |  | . |  |  |
| Template Predicted Secondary structure |   |
 |
|  |  | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  | . |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
120 | . | . | . | |
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
. | . |
|   |
|   |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | D | M | I | I | E | G | V | G | T | H | P | N | S | K | F | I | E | S | S | N | I | K | L | D | R | K | G | F | I | P | V | N | D | K | F | E | T | N | V | P | N | I | Y | . |
A | I | G | D | I | A | T | S | H | Y | R | H | V | D | L | P | A | S | V | P | L | A | W | G | A | H | R | A | A | S | I | V | A | E | Q |
| Query Conservation |   |
  |
|   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |
|
| . |
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|   |
|   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   | . | . |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |   |
|   |   |
|
|   |   |
| Template Sequence |   |
A | N | H | V | V | V | A | S | G | V | W | S | . |
. |
G | M | F | F | K | Q | L | G | L | N | N | A | D | G | K | P | Y | I | G | R | . |
. |
H | P | E | D | S | R | I | L | F | A | A | G | H | F | R | N | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | L | L | A | P | A | T | G | A | L | I | S | D | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| G | G | G | T | . | . |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
|
|  |  |  |  | . | . |  | T | T |  |  |  |  |  |  |  |  |
|
| S | S |
| T | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | T |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
195 | . | . | . | . | 200 | . | . | . | . | . | . | |
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | |
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
|   |
|   |   |
309 | 310 | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
| Query Sequence |   |
I | A | G | N | D | T |
| Query Conservation |   |
|   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
| Template Sequence |   |
I | M | N | K | E | V |
| Template Known Secondary structure |   |
 | T | T |
|
|
|
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|   |   |
346 | . | . | . | 350 | . |
|   |