|   |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | K | I | V | V | V | G | A | V | A | G | G | A | T | C | A | S | Q | I | R | R | L | D | K | E | S | D | I | I | I | F | E | K | D | R | D | M | S | F | A | . |
. |
. |
. |
N | C | A | L | P | Y | V | I | G | E | V | V | E | D | R | R | Y | A | L | A | Y | T | P | E | K | F | Y | D | R | K | Q | I | T | V | K | T |
| Query Conservation |   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   | . | . |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Template Sequence |   |
K | H | V | V | V | V | G | A | G | M | S | G | L | S | A | A | Y | V | L | S | G | A | . |
. |
G | H | Q | V | T | V | L | E | A | S | E | R | A | G | G | R | V | R | T | Y | R | N | D | K | E | D | W | Y | A | N | L | G | P | M | R | L | P | E | K | H | R | I | V | R | E | Y | I | R | K | F | G | L | Q | L | N | E |
| Template Known Secondary structure |   |
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |
| S | S | S | S | S |
| T | T |
|
|  |  |  |  | T | T | T | T |  |  |  |  | S | S |
|
|
|  |  | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
34 | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
|   |
|   |   |
78 | . | 80 | . | |
|
|
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | H | E | V | . |
. |
. |
I | A | I | N | D | E | R | Q | T | V | S | V | L | N | R | K | T | N | E | Q | F | E | E | S | Y | D | K | L | I | L | S | P | G | A | S | A | N | S | L | G | F | E | S | D | I | T | F | T | L | R | N | L | E | D | T | D | A | I | D | Q | F | I | K | A | N | Q | V | D | K | V | L | V | V |
| Query Conservation |   |
  |   |   |
| . | . | . |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
F | S | Q | E | N | D | N | A | W | Y | F | I | K | N | I | R | K | R | V | G | E | V | K | K | D | P | G | V | L | K | Y | P | V | K | P | S | E | E | G | K | S | A | G | Q | L | Y | E | E | S | L | G | K | V | V | E | E | L | K | R | T | N | C | S | Y | I | L | N | K | Y | D | T | Y | S | T | K | E | Y | L | L | K |
| Template Known Secondary structure |   |
|
| S |
|
| T | T | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| G | G | G | G |
|
|
|
|
| G | G | G | T | T |
|
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  | G | G | G | S | B |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
|   |
|   |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
| Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
| . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
| Query Sequence |   |
G | A | G | Y | V | S | L | E | V | L | E | N | L | N | E | R | G | L | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | T | L | I | H | R | S | D | K | I | N | K | L | M | D | A | D | M | N | Q | P | I | L | D | E | L | D | K | R | E | I | P | Y | R | L | N | E | E | I | N | A | I | N | G | N | E | . |
. |
. |
| Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
E | G | N | L | S | P | G | A | V | D | M | I | G | D | L | M | N | E | D | S | G | Y | Y | V | S | F | P | E | S | L | R | H | D | D | I | F | A | Y | E | K | R | F | D | E | I | V | G | G | M | D | K | L | P | T | S | M | Y | R | A | I | E | E | K | V | H | L | N | A | Q | V | I | K | I | Q | K | N | A | E | K | V |
| Template Known Secondary structure |   |
T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G | T | T | S | B |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  |  | T | G | G | G |  |  | S | S |
|  |  |  |  |  |  |  |  | T | T |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
|   |
|   |   |
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
I | T | F | K | S | G | K | V | E | H | Y | D | M | I | I | E | G | V | G | T | H | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | S | K | F | I | E | S | S | N | I | K | L | D | R | K | G | F | I | P | V | N | D | K | F | E | T | N | V | P | N | I | Y | A | I | G | D | I | A | T | S | H | Y | R |
| Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |
| Template Sequence |   |
T | V | V | Y | Q | T | P | A | K | E | M | A | S | V | T | A | D | Y | V | I | V | C | T | T | S | R | A | T | R | R | I | K | F | E | P | P | L | P | P | K | K | A | H | A | L | R | S | V | F | T | P | Y | Q | F | Q | H | F | S | E | S | L | T | A | S | V | D | R | I | Y | F | A | G | E | H | T | A | E | A | H | G |
| Template Known Secondary structure |   |
 |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  | S |  |  |  |  |
| S |
|  |  |  |  |  | T | S |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |
|
| B | T | T |  |  |  |
| S | G | G | G | S | S | S | T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
|   |
|   |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | V | D | L | P | A | S | V | P | L | A | W | G | A | H | R | A | A | S | I | V | A | E | Q | I |
| Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
| Alig confidence |   |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . | . | . | . | . | . | . |
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|
| Template Sequence |   |
W | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | D | S | T | I | K | S | G | L | R | A | A | R | D | V |
| Template Known Secondary structure |   |
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
465 | |
|
|
|
|
|
|
|
|
. | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
|   |