Job Description O52582 Confidence 100.00% Date Tue Jul 17 17:05:03 BST 2012 Rank 38 Aligned Residues 411 % Identity 19% Template c2cfyB_ PDB info PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin reductase 1; PDBTitle: crystal structure of human thioredoxin reductase 1 Resolution 2.7 Å

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.
Predicted Secondary structure																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	I	V	V	V	G	A	V	A	G	G	A	T	C	A	S	Q	I	R	R	L	D	K	E	S	D	I	I	I	F	E	K	D	R	D	M	S	F	A	N	C	A	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.	.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																							.	.
Template Sequence		D	L	I	I	I	G	G	G	S	G	G	L	A	A	A	K	E	A	A	Q	Y	.	.	G	K	K	V	M	V	L	D	F	V	T	P	T	P	L	G	T	R	W	G	L	G	G	T	C	V	N	V	G	C	I	P	K	K	L	M	H	Q	A	A	L	L	G	Q	A	L	Q	D	S	R	N	Y	G	W	K	V	E
Template Known Secondary structure									S												T	T	.	.	T													T	T						T	T							S																							T	T
Template Predicted Secondary structure																							.	.
Template SS confidence
		14	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.			.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
								46	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	P	Y	V	I	G	E	V	V	E	D	R	R	Y	A	L	A	Y	T	P	E	K	F	Y	D	R	K	Q	I	T	V	K	T	Y	H	E	V	I	A	I	N	D	E	R	Q	T	V	S	V	L	N	R	K	T	N	E	Q	F	E	E	S	Y	D	K	L	I	L	S	P	G	A	S	A	N	S
Query Conservation		.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.																																		.														.	.	.
Template Conservation																																									.														.	.	.
Template Sequence		E	T	V	K	H	D	W	D	R	M	I	E	A	V	Q	N	H	I	G	S	L	N	W	G	Y	R	V	A	L	R	E	K	K	V	V	Y	E	N	A	.	Y	G	Q	F	I	G	P	H	R	I	K	A	T	.	.	.	N	N	K	G	K	E	K	I	Y	S	A	E	R	F	L	I	A	T	G	E	R	P	R	Y
Template Known Secondary structure		S	S																														T	T							.							T	T						.	.	.		T	T	S
Template Predicted Secondary structure																																									.														.	.	.
Template SS confidence
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130		.	.	.	.	.	.	.	.	.	140	.	.	.				.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
		120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	G	F	E	S	D	I	T	F	T	L	R	N	L	E	D	T	D	A	I	D	Q	F	I	K	A	N	Q	V	D	K	V	L	V	V	G	A	G	Y	V	S	L	E	V	L	E	N	L	N	E	R	G	L	H	P	T	L	I	H	R	S	D	K	I	N	K	L	M	D	A	D	M	N	Q	P	I	L	D	E	L
Query Conservation
Alig confidence						.	.	.	.	.	.																																																							.
Template Conservation						.	.	.	.	.	.																																																							.
Template Sequence		L	G	I	P	.	.	.	.	.	.	G	D	K	E	Y	C	I	S	S	D	D	L	F	S	L	P	Y	C	P	G	K	T	L	V	V	G	A	S	Y	V	A	L	E	C	A	G	F	L	A	G	I	G	L	D	V	T	V	M	V	R	S	I	L	L	.	R	G	F	D	Q	D	M	A	N	K	I	G	E	H	M
Template Known Secondary structure			S	S	T	.	.	.	.	.	.	T						B						T	T		S	S				S							S													T	T								S	S		S	S	.	T	T	S
Template Predicted Secondary structure						.	.	.	.	.	.																																																							.
Template SS confidence
		168	.	170	.							.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.		.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.														220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.				.	.	.	.	.	.	260	.	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.	.	.	.	.	.	.																																			.	.	.
Query SS confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.																																			.	.	.
Query Sequence		D	K	R	E	I	P	Y	R	L	N	E	E	I	N	A	I	N	G	N	E	.	.	.	.	.	.	.	.	.	.	.	.	.	I	T	F	K	S	G	K	V	E	H	Y	D	M	I	I	E	G	V	G	T	H	P	N	S	K	F	I	E	S	S	N	I	K	L	.	.	.	D	R	K	G	F	I	P	V	N	D
Query Conservation																						.	.	.	.	.	.	.	.	.	.	.	.	.																																			.	.	.
Alig confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.																																			.	.	.
Template Conservation
Template Sequence		E	E	H	G	I	K	F	I	R	Q	F	V	P	I	K	V	E	Q	I	E	A	G	T	P	G	R	L	R	V	V	A	Q	S	T	N	S	E	E	I	I	E	G	E	Y	N	T	V	M	L	A	I	G	R	D	A	C	T	R	K	I	G	L	E	T	V	G	V	K	I	N	E	K	T	G	K	I	P	V	T	D
Template Known Secondary structure				T	T						S												S	T	T										S	S	S	S								S						S					S		S	S	S		G	G	G	T	T					T	T	T			B				T
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		264	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	F	E	T	N	V	P	N	I	Y	A	I	G	D	I	A	T	S	H	Y	R	H	V	D	L	P	A	S	V	P	L	A	W	G	A	H	R	A	A	S	I	V	A	E	Q	I	A	G	N	D	T	I	E	F	K	G	F	L	G	N	N	I	V	K	F	F	D	Y	T	F	A	S	V	G	V	K	P	N	E	L
Query Conservation
Alig confidence																					.	.	.	.	.	.	.	.	.																										.
Template Conservation																					.	.	.	.	.	.	.	.	.																										.
Template Sequence		E	E	Q	T	N	V	P	Y	I	Y	A	I	G	D	I	L	E	D	K	.	.	.	.	.	.	.	.	.	V	E	L	T	P	V	A	I	Q	A	G	R	L	L	A	Q	R	L	Y	A	G	S	T	V	K	.	C	D	Y	E	N	V	P	T	T	V	F	T	P	L	E	Y	G	A	C	G	L	S	E	E	K	A
Template Known Secondary structure		T	S	B		S	S	T	T					S	T	T	B	T	T	S	.	.	.	.	.	.	.	.	.																				S						.				S	S							S	S	S
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.																										.
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.										340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.		.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
		344	.	.	.	.	.	350	.	.	.	.	.	.							.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.		.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure															.	.	.	.	.	.																				.
Query SS confidence															.	.	.	.	.	.																				.
Query Sequence		K	Q	F	D	Y	K	M	V	E	V	T	Q	G	.	.	.	.	.	.	A	H	A	N	Y	Y	P	G	N	S	P	L	H	L	R	V	Y	Y	D	.	T	S	N	R	Q	I	L	R	A	A	A	V	G	K	E	G	A	D	K	R	I	D	V	L	S	M	A	M	M	N	Q	L	T	V	D	E	L	T	E	F	E
Query Conservation															.	.	.	.	.	.																				.
Alig confidence															.	.	.	.	.	.																				.																.
Template Conservation																																																								.
Template Sequence		V	E	K	F	G	E	E	N	I	E	V	Y	H	S	Y	F	W	P	L	E	W	T	I	P	S	R	D	N	N	K	C	Y	A	K	I	I	C	N	T	K	D	N	E	R	V	V	G	F	H	V	L	G	P	N	.	A	G	E	V	T	Q	G	F	A	A	A	L	K	C	G	L	T	K	K	Q	L	D	S	T	I
Template Known Secondary structure							G	G	G											G	G	G	T	T	T	T			T	T										G	G	G	T	T									S	T	T	.														T	T		B							S
Template Predicted Secondary structure																																																								.
Template SS confidence
		391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.		.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	A	Y	A	P	P	Y	S	H	P	K	D	L	I	N	M	I	G	Y	K	A	K
Query Conservation
Alig confidence				.
Template Conservation				.
Template Sequence		G	I	.	H	P	V	C	A	E	V	F	T	T	L	S	V	T	K	R	S	G	A
Template Known Secondary structure				.	T	T		G	G	G	G	G	G	S				B	T	T	T
Template Predicted Secondary structure				.
Template SS confidence
		470	.		.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490