Job Description O52582 Confidence 100.00% Date Tue Jul 17 17:05:03 BST 2012 Rank 35 Aligned Residues 409 % Identity 19% Template c2a8xA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrolipoyl dehydrogenase; PDBTitle: crystal structure of lipoamide dehydrogenase from2 mycobacterium tuberculosis Resolution 2.40 Å

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.																																		40	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	I	V	V	V	G	A	V	A	G	G	A	T	C	A	S	Q	I	R	R	L	D	K	E	S	D	I	I	I	F	E	K	D	R	D	M	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	A	N	C	A	L	P	Y	V	I
Query Conservation																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.	.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																							.	.
Template Sequence		D	V	V	V	L	G	A	G	P	G	G	Y	V	A	A	I	R	A	A	Q	L	.	.	G	L	S	T	A	I	V	E	P	K	Y	W	G	G	V	C	L	N	V	G	C	I	P	S	K	A	L	L	R	N	A	E	L	V	H	I	F	T	K	D	A	K	A	F	G	I	S	G	E	V	T	F	D	Y	G	I	A
Template Known Secondary structure									S													T	.	.	T								S	S		T	T							S																					T	T	T	T	T			S
Template Predicted Secondary structure																							.	.
Template SS confidence
		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.			.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
		50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	E	V	V	E	D	R	R	Y	A	L	A	Y	T	P	E	K	F	Y	D	R	K	Q	I	T	V	K	T	Y	H	E	V	I	A	I	N	D	E	R	Q	T	V	S	V	L	N	R	K	T	N	E	Q	F	E	E	S	Y	D	K	L	I	L	S	P	G	A	S	A	N	S	L	G	F	E	S	D	I	T	F	T
Query Conservation
Alig confidence																															.	.	.	.
Template Conservation																															.	.	.	.
Template Sequence		Y	D	R	S	R	K	V	A	E	G	R	V	A	G	V	H	F	L	X	K	K	N	K	I	T	E	I	H	G	.	.	.	.	Y	G	T	F	A	D	A	N	T	L	L	V	D	L	N	D	G	G	T	E	S	V	T	F	D	N	A	I	I	A	T	G	S	S	T	R	L	V	P	G	T	S	L	S	A	N	V
Template Known Secondary structure																							T	T							.	.	.	.					S	S	S	S							T	T	S																						T	T				B	T	T
Template Predicted Secondary structure																															.	.	.	.
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.					.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	N	L	E	D	T	D	A	I	D	Q	F	I	K	A	N	Q	V	D	K	V	L	V	V	G	A	G	Y	V	S	L	E	V	L	E	N	L	N	E	R	G	L	H	P	T	L	I	H	R	S	D	K	I	N	K	L	M	D	A	D	M	N	Q	P	I	L	D	E	L	D	K	R	E	I	P	Y	R	L	N
Query Conservation
Alig confidence														.	.	.	.	.	.
Template Conservation														.	.	.	.	.	.
Template Sequence		V	T	Y	E	E	Q	I	L	S	R	E	L	.	.	.	.	.	.	P	K	S	I	I	I	A	G	A	G	A	I	G	X	E	F	G	Y	V	L	K	N	Y	G	V	D	V	T	I	V	E	F	L	P	R	A	L	P	N	E	D	A	D	V	S	K	E	I	E	K	Q	F	K	K	L	G	V	T	I	L	T	A
Template Known Secondary structure									T		S	S		.	.	.	.	.	.		S								S													T	T								S	S	S	S	S	S	T	T	S																T						S
Template Predicted Secondary structure														.	.	.	.	.	.
Template SS confidence
		159	160	.	.	.	.	.	.	.	.	.	170							.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.								.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.			.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Predicted Secondary structure															.	.	.	.	.	.	.																								.	.
Query SS confidence															.	.	.	.	.	.	.																								.	.
Query Sequence		E	E	I	N	A	I	N	G	N	E	I	T	F	.	.	.	.	.	.	.	K	S	G	K	V	E	H	Y	D	M	I	I	E	G	V	G	T	H	P	N	S	K	F	.	.	I	E	S	S	N	I	K	L	D	R	K	G	F	I	P	V	N	D	K	F	E	T	N	V	P	N	I	Y	A	I	G	D	I	A	T
Query Conservation															.	.	.	.	.	.	.																								.	.
Alig confidence															.	.	.	.	.	.	.																								.	.
Template Conservation
Template Sequence		T	K	V	E	S	I	A	D	G	G	S	Q	V	T	V	T	V	T	K	D	G	V	A	Q	E	L	K	A	E	K	V	L	Q	A	I	G	F	A	P	N	V	E	G	Y	G	L	D	K	A	G	V	A	L	T	D	R	K	A	I	G	V	D	D	Y	X	R	T	N	V	G	H	I	Y	A	I	G	D	V	N	G
Template Known Secondary structure											S	S								S	S	S								S						S							S	S	S						T			B		T	T	S	S	B				T	T	S	B		S	S	T	T					G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Predicted Secondary structure
Query SS confidence
Query Sequence		S	H	Y	R	H	V	D	L	P	A	S	V	P	L	A	W	G	A	H	R	A	A	S	I	V	A	E	Q	I	A	G	N	D	T	I	E	F	K	G	F	L	G	N	N	I	V	K	F	F	D	Y	T	F	A	S	V	G	V	K	P	N	E	L	K	Q	F	D	Y	K	M	V	E	V	T	Q	G	A	H	A	N
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	L	L	Q	L	A	H	V	A	E	A	Q	G	V	V	A	A	E	T	I	A	G	A	E	T	L	T	L	G	D	H	R	X	L	P	R	A	T	F	C	Q	P	N	V	A	S	F	G	L	T	E	Q	Q	A	R	N	E	G	Y	D	V	V	V	A	K	F	P	F	T	A	N
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	S	S		S																	T									G	G	G	S						S	S	S															T	T										G	G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.
Template SS confidence
												313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
		361				.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
Predicted Secondary structure			.	.	.
Query SS confidence			.	.	.
Query Sequence		Y	.	.	.	Y	P	G	N	S	P	L	H	L	R	V	Y	Y	D	T	S	N	R	Q	I	L	R	A	A	A	V	G	K	E	G	A	D	K	R	I	D	V	L	S	M	A	M	M	N	Q	L	T	V	D	E	L	T	E	F	E	V	A	Y	A	P	P	Y	S	H	P	K	D	L	I	N	M	I	G	Y
Query Conservation			.	.	.
Alig confidence			.	.	.																														.																												.
Template Conservation																																			.																												.
Template Sequence		A	K	A	H	G	V	G	D	P	S	G	F	V	K	L	V	A	D	A	K	H	G	E	L	L	G	G	H	L	V	G	H	D	.	V	A	E	L	L	P	E	L	T	L	A	Q	R	W	D	L	T	A	S	E	L	A	R	N	V	H	T	.	H	P	T	X	S	E	A	L	Q	E	C	F	H	G	L	V
Template Known Secondary structure								T												T	T	T	T										T	T	.	G	G	G	G										T	T		B					T	T	S				.	T	T		T	T
Template Predicted Secondary structure																																			.																												.
Template SS confidence
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.		.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.		.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.