Job Description O52582 Confidence 100.00% Date Tue Jul 17 17:05:03 BST 2012 Rank 40 Aligned Residues 403 % Identity 18% Template c1bwcA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:protein (glutathione reductase); PDBTitle: structure of human glutathione reductase complexed with ajoene2 inhibitor and subversive substrate Resolution 2.10 Å

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		1	.	.			.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.																																		.	.	.	40	.	.	.	.	.
Predicted Secondary structure					.	.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence					.	.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	P	K	.	.	I	V	V	V	G	A	V	A	G	G	A	T	C	A	S	Q	I	R	R	L	D	K	E	S	D	I	I	I	F	E	K	D	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	M	S	F	A	N	C	A	L
Query Conservation					.	.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence					.	.																					.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																											.	.
Template Sequence		V	A	S	Y	D	Y	L	V	I	G	G	G	S	G	G	L	A	S	A	R	R	A	A	E	L	.	.	G	A	R	A	A	V	V	E	S	H	K	L	G	G	T	C	V	N	V	G	C	V	P	K	K	V	M	W	N	T	A	V	H	S	E	F	M	H	D	H	A	D	Y	G	F	P	S	C	E	G	K	F	N
Template Known Secondary structure						S							S													T	.	.	T								S	S		T	T						S	S																				T	G	G	G	T	S
Template Predicted Secondary structure																											.	.
Template SS confidence
		18	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.			.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.
		46	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	Y	V	I	G	E	V	V	E	D	R	R	Y	A	L	A	Y	T	P	E	K	F	Y	D	R	K	Q	I	T	V	K	T	Y	H	E	V	I	A	I	N	D	E	R	Q	T	V	S	V	L	N	R	K	T	N	E	Q	F	E	E	S	Y	D	K	L	I	L	S	P	G	A	S	A	N	S	L	G	F	E	S	D
Query Conservation
Alig confidence																																																					.	.	.	.	.	.	.
Template Conservation																																																					.	.	.	.	.	.	.
Template Sequence		W	R	V	I	K	E	K	R	D	A	Y	V	S	R	L	N	A	I	Y	Q	N	N	L	T	K	S	H	I	E	I	I	R	G	H	A	A	F	T	S	D	P	K	P	T	I	E	V	S	G	K	K	.	.	.	.	.	.	.	Y	T	A	P	H	I	L	I	A	T	G	G	M	P	S	T	P	H	E	S	Q	I
Template Known Secondary structure																											T	T						S						S		S	S						T	T			.	.	.	.	.	.	.				S															T	T	T	S
Template Predicted Secondary structure																																																					.	.	.	.	.	.	.
Template SS confidence
		96	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.								.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.
		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	T	F	T	L	R	N	L	E	D	T	D	A	I	D	Q	F	I	K	A	N	Q	V	D	K	V	L	V	V	G	A	G	Y	V	S	L	E	V	L	E	N	L	N	E	R	G	L	H	P	T	L	I	H	R	S	D	K	I	N	K	L	M	D	A	D	M	N	Q	P	I	L	D	E	L	D	K	R	E	I	P
Query Conservation
Alig confidence													.	.	.	.
Template Conservation													.	.	.	.
Template Sequence		P	G	A	S	L	G	I	T	S	D	G	.	.	.	.	F	F	Q	L	E	E	L	P	G	R	S	V	I	V	G	A	G	Y	I	A	V	E	M	A	G	I	L	S	A	L	G	S	K	T	S	L	M	I	R	H	D	K	V	L	R	S	F	D	S	M	I	S	T	N	C	T	E	E	L	E	N	A	G	V	E
Template Known Secondary structure		T	T	G	G	G	S	B					.	.	.	.		T	T			S			S								S														T								S	S	S	S	S		T	T	S															T	T
Template Predicted Secondary structure													.	.	.	.
Template SS confidence
		169	170	.	.	.	.	.	.	.	.	.					180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
		206	.	.	.	210	.	.	.	.	.	.														.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.			.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.
Query SS confidence													.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.
Query Sequence		Y	R	L	N	E	E	I	N	A	I	N	.	.	.	.	.	.	.	.	.	.	.	.	.	G	N	E	I	T	F	K	S	G	K	V	E	H	Y	D	M	I	I	E	G	V	G	T	H	P	N	S	K	F	.	.	I	E	S	S	N	I	K	L	D	R	K	G	F	I	P	V	N	D	K	F	E	T	N	V	P
Query Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.																														.	.
Template Conservation
Template Sequence		V	L	K	F	S	Q	V	K	E	V	K	K	T	L	S	G	L	E	V	S	M	V	T	A	V	P	G	R	L	P	V	M	T	M	I	P	D	V	D	C	L	L	W	A	I	G	R	V	P	N	T	K	D	L	S	L	N	K	L	G	I	Q	T	D	D	K	G	H	I	I	V	D	E	F	Q	N	T	N	V	K
Template Known Secondary structure				T	T										T	T											T	T	S											S						S					S		T	T	S		G	G	G	T	T			B		T	T			B				T	T		B		S	S	T
Template Predicted Secondary structure
Template SS confidence
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.
		271	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.			.
Predicted Secondary structure																																																																															.	.
Query SS confidence																																																																															.	.
Query Sequence		N	I	Y	A	I	G	D	I	A	T	S	H	Y	R	H	V	D	L	P	A	S	V	P	L	A	W	G	A	H	R	A	A	S	I	V	A	E	Q	I	A	G	N	D	T	I	E	F	K	G	F	L	G	N	N	I	V	K	F	F	D	Y	T	F	A	S	V	G	V	K	P	N	E	L	K	Q	F	D	.	.	Y
Query Conservation																																																																															.	.
Alig confidence														.	.	.	.	.	.	.	.	.	.																																																								.	.
Template Conservation														.	.	.	.	.	.	.	.	.	.
Template Sequence		G	I	Y	A	V	G	D	V	C	G	K	A	.	.	.	.	.	.	.	.	.	.	L	L	T	P	V	A	I	A	A	G	R	K	L	A	H	R	L	F	E	Y	K	E	D	S	K	L	D	Y	N	N	I	P	T	V	V	F	S	H	P	P	I	G	T	V	G	L	T	E	D	E	A	I	H	K	Y	G	I	E
Template Known Secondary structure		T					G	G	G	G	T	S	S	.	.	.	.	.	.	.	.	.	.																			S			T	T						S	S								S	S																		G	G
Template Predicted Secondary structure														.	.	.	.	.	.	.	.	.	.
Template SS confidence
		325	.	.	.	.	330	.	.	.	.	.	.											.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
		349	350	.	.	.	.	.	.	.	.	.	360	.	.				.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.
Predicted Secondary structure																.	.	.
Query SS confidence																.	.	.
Query Sequence		K	M	V	E	V	T	Q	G	A	H	A	N	Y	Y	.	.	.	P	G	N	S	P	L	H	L	R	V	Y	Y	D	T	S	N	R	Q	I	L	R	A	A	A	V	G	K	E	G	A	D	K	R	I	D	V	L	S	M	A	M	M	N	Q	L	T	V	D	E	L	T	E	F	E	V	A	Y	A	P	P	Y	S	H
Query Conservation																.	.	.
Alig confidence																.	.	.																													.																												.
Template Conservation																																															.																												.
Template Sequence		N	V	K	T	Y	S	T	S	F	T	P	M	Y	H	A	V	T	K	R	K	T	K	C	V	M	K	M	V	C	A	N	K	E	E	K	V	V	G	I	H	M	Q	G	L	G	.	C	D	E	M	L	Q	G	F	A	V	A	V	K	M	G	A	T	K	A	D	F	D	N	T	V	A	I	.	H	P	T	S	S	E
Template Known Secondary structure		G											G	G	G	G	G		S	S												T	T	T	T									S	T	T	.														T	T		B						T	S				.	T	T		S	G	G
Template Predicted Secondary structure																																															.																												.
Template SS confidence
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.		.	.	.	470	.	.
		426	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	K	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	L	V
Template Known Secondary structure		G	G	G
Template Predicted Secondary structure
Template SS confidence
		473	.	.