Email l.a.kelley@imperial.ac.uk Description A2AAY5 Date Tue Jul 30 13:00:07 BST 2013 Unique Job ID f8c6a4defb6bed86

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2dybA_ 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox) 2 c1ng2A_ 100.0 34 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 3 c2lqnA_ 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl 4 c1griA_ 99.9 23 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 5 c1ov3A_ 99.9 42 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 6 c2eyzA_ 99.9 19 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii 7 c2l3sA_ 99.9 20 PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk 8 c2l73A_ 99.9 21 PDB header:oxidoreductase regulator Chain: A: PDB Molecule:nadph oxidase organizer 1; PDBTitle: structure of the noxo1b px domain 9 d1kq6a_ 99.9 36 Fold:PX domain Superfamily:PX domain Family:PX domain 10 d1h6ha_ 99.9 26 Fold:PX domain Superfamily:PX domain Family:PX domain 11 c1mv3A_ 99.9 12 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc 12 d1o7ka_ 99.9 36 Fold:PX domain Superfamily:PX domain Family:PX domain 13 c2reaA_ 99.8 32 PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 PDBTitle: crystal structures of c2alpha-pi3 kinase px-domain domain2 indicate conformational change associated with ligand3 binding. 14 c2iwlX_ 99.7 28 PDB header:transferase Chain: X: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 PDBTitle: structure of the px domain of phosphoinositide 3-kinase-2 c2alpha 15 c2egcA_ 99.7 51 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein 16 c2czoA_ 99.7 30 PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of the px domain of bem1p 17 d1udla_ 99.7 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 18 d1ng2a2 99.7 34 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 19 c2rqrA_ 99.7 16 PDB header:protein binding Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex 20 c2dx1A_ 99.6 28 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 21 c2wweA_ not modelled 99.6 23 PDB header:transferase Chain: A: PDB Molecule:phosphoinositide-3-kinase, class 2, gamma PDBTitle: crystal structure of the phox homology domain of human2 phosphoinositide-3-kinase-c2-gamma 22 c2yt6A_ not modelled 99.6 21 PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1 23 c2jxbA_ not modelled 99.6 18 PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex 24 d1ue9a_ not modelled 99.6 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 25 c2d8jA_ not modelled 99.6 26 PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh3 domain of fyn-related kinase 26 d1ov3a2 not modelled 99.6 36 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 27 c2dbkA_ not modelled 99.6 19 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structures of the sh3 domain of human crk-like2 protein 28 c2e5kA_ not modelled 99.6 18 PDB header:protein binding Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1; PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1 29 d1phta_ not modelled 99.5 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 30 c1zukA_ not modelled 99.5 19 PDB header:contractile protein Chain: A: PDB Molecule:myosin tail region-interacting protein mti1; PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17 31 c2ct3A_ not modelled 99.5 21 PDB header:signaling protein Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the sh3 domain of the vinexin protein 32 c2jmcA_ not modelled 99.5 20 PDB header:signaling protein Chain: A: PDB Molecule:spectrin alpha chain, brain and p41 peptide PDBTitle: chimer between spc-sh3 and p41 33 c2fpeB_ not modelled 99.5 14 PDB header:signaling protein Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein PDBTitle: conserved dimerization of the ib1 src-homology 3 domain 34 c3rnjA_ not modelled 99.5 24 PDB header:protein binding Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2) 35 c3nmzD_ not modelled 99.5 25 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 36 c1zlmA_ not modelled 99.5 29 PDB header:signaling protein Chain: A: PDB Molecule:osteoclast stimulating factor 1; PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor 37 c2ke9A_ not modelled 99.5 19 PDB header:protein binding Chain: A: PDB Molecule:caskin-2; PDBTitle: nmr solution structure of the caskin sh3 domain 38 c2kymA_ not modelled 99.5 17 PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide 39 c2cucA_ not modelled 99.5 23 PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2 40 c4afzC_ not modelled 99.5 30 PDB header:hydrolase/de novo protein Chain: C: PDB Molecule:fynomer; PDBTitle: human chymase - fynomer complex 41 c2lj0A_ not modelled 99.5 25 PDB header:signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: the third sh3 domain of r85fl 42 c2yupA_ not modelled 99.5 23 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the second sh3 domain of human vinexin 43 d1wlpb2 not modelled 99.5 44 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 44 c2oi3A_ not modelled 99.5 28 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1) 45 c1x6gA_ not modelled 99.5 16 PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase. 46 d1efna_ not modelled 99.5 32 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 47 c2rf0D_ not modelled 99.5 31 PDB header:transferase Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10; PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain 48 c2cudA_ not modelled 99.5 19 PDB header:signaling protein Chain: A: PDB Molecule:src-like-adapter; PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap) 49 c2ebpA_ not modelled 99.5 19 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 50 c2kt1A_ not modelled 99.5 22 PDB header:protein binding Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e 51 c2yunA_ not modelled 99.5 29 PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin 52 c2j06B_ not modelled 99.5 23 PDB header:signal transduction Chain: B: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution 53 c2ed1A_ not modelled 99.5 25 PDB header:signaling protein Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate- PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein 54 c1x2qA_ not modelled 99.5 22 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 55 c2eyxA_ not modelled 99.5 17 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase 56 c1zuyB_ not modelled 99.5 30 PDB header:contractile protein Chain: B: PDB Molecule:myosin-5 isoform; PDBTitle: high-resolution structure of yeast myo5 sh3 domain 57 c2eyyA_ not modelled 99.5 23 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 58 c3cqtA_ not modelled 99.5 31 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: n53i v55l mutant of fyn sh3 domain 59 c1x2pA_ not modelled 99.5 24 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 2; PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2 60 d1gcqc_ not modelled 99.5 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 61 d1shfa_ not modelled 99.5 32 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 62 c4glmD_ not modelled 99.5 21 PDB header:signaling protein Chain: D: PDB Molecule:dynamin-binding protein; PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens] 63 c2xmfA_ not modelled 99.5 24 PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 64 c2lcsA_ not modelled 99.5 25 PDB header:transferase, signaling protein Chain: A: PDB Molecule:nap1-binding protein 2; PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p 65 d1spka_ not modelled 99.5 21 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 66 d1wfwa_ not modelled 99.5 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 67 c1x6bA_ not modelled 99.5 21 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16; PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16 68 c3qwyA_ not modelled 99.5 22 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 69 c2df6A_ not modelled 99.5 39 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2 70 c1yn8E_ not modelled 99.5 28 PDB header:unknown function Chain: E: PDB Molecule:nap1-binding protein 2; PDBTitle: sh3 domain of yeast nbp2 71 c2dmoA_ not modelled 99.5 19 PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) 72 d1fmka1 not modelled 99.5 29 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 73 d1pwta_ not modelled 99.5 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 74 c2kgtA_ not modelled 99.5 27 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase 6; PDBTitle: solution structure of sh3 domain of ptk6 75 c2dl4A_ not modelled 99.5 22 PDB header:signaling protein Chain: A: PDB Molecule:protein stac; PDBTitle: solution structure of the first sh3 domain of stac protein 76 d1uuea_ not modelled 99.5 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 77 d1u06a1 not modelled 99.5 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 78 d1e6ga_ not modelled 99.5 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 79 c2l0aA_ not modelled 99.5 23 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e 80 d1uffa_ not modelled 99.5 32 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 81 c2js0A_ not modelled 99.5 33 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of second sh3 domain of adaptor nck 82 c1negA_ not modelled 99.5 18 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin 83 d1nega_ not modelled 99.5 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 84 d1gl5a_ not modelled 99.5 33 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 85 d1k1za_ not modelled 99.5 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 86 c2cubA_ not modelled 99.5 30 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 87 c2bzxA_ not modelled 99.5 19 PDB header:sh3 domain Chain: A: PDB Molecule:crk-like protein; PDBTitle: atomic model of crkl-sh3c monomer 88 c2nwmA_ not modelled 99.5 16 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 89 c2eqiA_ not modelled 99.5 22 PDB header:immune system, hydrolase Chain: A: PDB Molecule:phospholipase c, gamma 2; PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2 90 c1x27F_ not modelled 99.5 33 PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas 91 c1bb9A_ not modelled 99.5 20 PDB header:transferase Chain: A: PDB Molecule:amphiphysin 2; PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2 92 d1bb9a_ not modelled 99.5 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 93 d1e6ha_ not modelled 99.5 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 94 c2ed0A_ not modelled 99.5 32 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 95 c1x69A_ not modelled 99.5 20 PDB header:signaling protein Chain: A: PDB Molecule:cortactin isoform a; PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin 96 d1uj0a_ not modelled 99.5 27 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 97 c2ysqA_ not modelled 99.5 25 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9 98 c2egeA_ not modelled 99.5 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein kiaa1666; PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein 99 d1uhca_ not modelled 99.5 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 100 c2dl3A_ not modelled 99.4 15 PDB header:cell adhesion, signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1 101 d1jo8a_ not modelled 99.4 25 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 102 c4esrB_ not modelled 99.4 23 PDB header:protein binding Chain: B: PDB Molecule:jouberin; PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors 103 d1wiea_ not modelled 99.4 21 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 104 c3qwxX_ not modelled 99.4 24 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 105 c2jteA_ not modelled 99.4 17 PDB header:signaling protein Chain: A: PDB Molecule:cd2-associated protein; PDBTitle: third sh3 domain of cd2ap 106 d1gcqa_ not modelled 99.4 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 107 c2i0nA_ not modelled 99.4 13 PDB header:structural protein Chain: A: PDB Molecule:class vii unconventional myosin; PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region 108 d1k4us_ not modelled 99.4 25 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 109 d1arka_ not modelled 99.4 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 110 c2d8hA_ not modelled 99.4 25 PDB header:unknown function Chain: A: PDB Molecule:sh3yl1 protein; PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1 111 c2pqhA_ not modelled 99.4 18 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal 112 c2dnuA_ not modelled 99.4 41 PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human 113 d1wlpb1 not modelled 99.4 37 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 114 d1ov3a1 not modelled 99.4 45 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 115 c2epdA_ not modelled 99.4 28 PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4 116 d1ujya_ not modelled 99.4 33 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 117 c1x43A_ not modelled 99.4 14 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:sh3 domain grb2-like protein b1; PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1) 118 d1k9aa1 not modelled 99.4 25 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 119 d1h8ka_ not modelled 99.4 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 120 d2iima1 not modelled 99.4 32 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain