|   |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
. | . | . | 300 | . | . | . | . | . | . | |
|
|
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | P | R | E | S | L | R | L | E | V | K | L | G | Q | G | C | F | G | E | V | W | M | G | T | W | N | G | . |
T | T | R | V | A | I | K | T | L | K | . |
. |
. |
. |
P | G | T | M | S | P | E | A | F | L | Q | E | A | Q | V | M | K | K |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |   | . |   |   |   |
|
|
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
| Template Sequence |   |
L | T | M | N | D | F | S | V | H | R | I | I | G | R | G | G | F | G | E | V | Y | G | C | R | K | A | D | T | G | K | M | Y | A | M | K | C | L | D | K | K | R | I | K | M | K | Q | G | E | T | L | A | L | N | E | R | I | M | L | S | L |
| Template Known Secondary structure |   |
|
| S | T | T |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
|   |
|   |   |
325 | |
|
|
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | |
. | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
| Predicted Secondary structure |   |
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | . |
. |
. |
R | H | E | K | L | V | Q | L | Y | A | V | V | S | E | E | P | . |
I | Y | I | V | T | E | Y | M | N | K | G | S | L | L | D | F | L | K | G | E | T | G | K | Y | L | R | L | P | Q | L | V | D | M | S | A | Q | I | A | S |
| Query Conservation |   |
| . | . | . |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | S | T | G | D | C | P | F | I | V | C | M | S | Y | A | F | H | T | P | D | K | L | S | F | I | L | D | L | M | N | G | G | D | L | H | Y | H | L | S | Q | H | G | . |
. |
V | F | S | E | A | D | M | R | F | Y | A | A | E | I | I | L |
| Template Known Secondary structure |   |
 | S | S | S |
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |
|
|
|
| S |
| B |  |  |  |  |  |  |  |  |
| . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
|   |
|   |   |
381 | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | M | A | Y | V | E | R | M | N | Y | V | H | R | D | L | R | A | A | N | I | L | V | G | E | N | L | V | C | K | V | A | D | F | G | L | A | R | L | I | E | D | N | E | Y | T | A | R | Q | G | A | K | F | P | I | K | W | T | A | P | E |
| Query Conservation |   |
  |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | L | E | H | M | H | N | R | F | V | V | Y | R | D | L | K | P | A | N | I | L | L | D | E | H | G | H | V | R | I | S | D | L | G | L | A | C | D | F | S | K | K | K | P | . |
. |
H | A | S | V | G | T | H | G | Y | M | A | P | E | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| S | S | S |
|  |  |  |
|
|
| T | T |
|  |  |
| S | S | S |
|
| . | . |
| S |
|
| S |
| G | G | G |
|
|  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
|
. | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
|   |
|   |   |
441 | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | |
|
. | . | . | . | 490 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | A | L | Y | G | R | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | L | T | T | K | G | R | V | P | Y | P | G | M | V | N | R | E | V | L | D | Q | V | E | R | . |
. |
G | Y | R | M | P | C | P | P | E | C | P | E | S |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |   |
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| Template Sequence |   |
L | Q | K | G | V | A | Y | D | S | S | A | D | W | F | S | L | G | C | M | L | F | K | L | L | R | . |
G | H | S | P | F | R | Q | H | K | T | K | D | K | H | E | I | D | R | M | T | L | T | M | A | V | E | L | P | D | S | F | S | P | E |
| Template Known Secondary structure |   |
 | S | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S |
| S | S |
|  |  |  |  |  |  |  | S | S | S |
|
|
|
|
|
| S | S | S |
|  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
362 | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
|   |
|   |   |
499 | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 520 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | H | D | L | M | C | Q | C | W | R | K | E | P | E | E | R | P | T | . |
. |
. |
. |
. |
F | E | Y | L | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
F | L | E | D | Y | F | T | S | T | E | P | Q | Y | Q | P | G | E | N | L |
| Query Conservation |   |
  |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|   | . | . | . | . | . |   |   |   |
|   |   | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | R | S | L | L | E | G | L | L | Q | R | D | V | N | R | R | L | G | C | L | G | R | G | A | Q | E | V | K | E | S | P | F | F | R | S | L | D | W | Q | M | V | F | L | Q | K | Y | P | P | P | L | I | P | P | R | G | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
| S | S | T | T | T | S | T | T | T | S | S | S | T |  |  |  |  |  | T | S | G | G | G | T | T |
|
|  |  |  |  |  | T | T |
| S |
|
| S |
|
|
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
421 | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
|   |