Job Description P05480 Confidence 100.00% Date Tue Jul 30 13:01:21 BST 2013 Rank 134 Aligned Residues 240 % Identity 41% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K	K	L
Query Conservation
Alig confidence																																												.	.	.	.	.	.	.
Template Conservation																																												.	.	.	.	.	.	.
Template Sequence		G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	K	E	.	.	.	.	.	.	.	F	I	E	E	A	K	V	M	M	N	L
Template Known Secondary structure		G	G	G	B			G	G	G									S	T	T	S	S								T	T	T											.	.	.	.	.	.	.		T	T
Template Predicted Secondary structure																																												.	.	.	.	.	.	.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.								.	.	.	.	.	440	.	.	.	.	.
		326	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.		.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Predicted Secondary structure																		.
Query SS confidence																		.
Query Sequence		R	H	E	K	L	V	Q	L	Y	A	V	V	S	E	E	P	.	I	Y	I	V	T	E	Y	M	N	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	S	A	Q	I	A	S	G	M	A	Y
Query Conservation																		.
Alig confidence																		.																					.
Template Conservation																																							.
Template Sequence		S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	.	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y
Template Known Secondary structure				T	T	B									S	S	S	S									T	T										G	.	G	G
Template Predicted Secondary structure																																							.
Template SS confidence
		453	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.		490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.
		385	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y
Query Conservation
Alig confidence																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	F	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	R	W	S	P	P	E	V	L	M	Y
Template Known Secondary structure					T	T				S			S	G	G	G					T	T												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	G
Template Predicted Secondary structure																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		512	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.																		.	.	.	.	.	.	550	.	.	.	.
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	K	V	Y	T	I	M	Y
Template Known Secondary structure																						T	T	S			T	T	T	T	S											T	T							T	T	S
Template Predicted Secondary structure
Template SS confidence
		572	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.
		505	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V	M	D	E
Template Known Secondary structure			T	T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		632	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D