Job Description P05480 Confidence 100.00% Date Tue Jul 30 13:01:21 BST 2013 Rank 195 Aligned Residues 255 % Identity 36% Template c2yhvA_ PDB info PDB header:transferase Chain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase Resolution 1.90 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.			.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.
Predicted Secondary structure																																											.	.
Query SS confidence																																											.	.
Query Sequence		D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	.	.	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K
Query Conservation																																											.	.
Alig confidence														.	.	.															.	.											.	.
Template Conservation														.	.	.															.	.
Template Sequence		D	L	K	E	V	P	R	K	N	I	T	L	.	.	.	I	R	G	L	A	F	G	E	V	Y	E	G	Q	V	.	.	P	L	Q	V	A	V	K	T	L	P	E	V	C	S	E	Q	D	E	L	D	F	L	M	E	A	L	I	I	S
Template Known Secondary structure		G	S		B			G	G	G				.	.	.							S								.	.											S	S
Template Predicted Secondary structure														.	.	.															.	.
Template SS confidence
		1107	.	.	1110	.	.	.	.	.	.	.	.				.	1120	.	.	.	.	.	.	.	.	.	1130	.	.			.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.
		324	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.		340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.						.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
Predicted Secondary structure																		.																							.	.	.	.	.
Query SS confidence																		.																							.	.	.	.	.
Query Sequence		K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	E	.	E	P	I	Y	I	V	T	E	Y	M	N	K	G	S	L	L	D	F	L	K	G	E	.	.	.	.	.	T	G	K	Y	L	R	L	P	Q	L	V	D	M	S	A	Q
Query Conservation																		.																							.	.	.	.	.
Alig confidence																		.																							.	.	.	.	.
Template Conservation
Template Sequence		K	F	N	H	Q	N	I	V	R	C	I	G	V	S	L	Q	S	L	P	R	F	I	L	M	E	L	M	A	G	G	D	L	K	S	F	L	R	E	T	R	P	R	P	S	Q	P	S	S	L	A	M	L	D	L	L	H	V	A	R	D
Template Known Secondary structure						T	T	B									S	S	S	S									T	T										T				S	S	S	T	T	S
Template Predicted Secondary structure
Template SS confidence
		1173	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T
Query Conservation
Alig confidence																																										.	.
Template Conservation																																										.	.
Template Sequence		I	A	C	G	C	Q	Y	L	E	E	N	H	F	I	H	R	D	I	A	A	R	N	C	L	L	T	C	P	G	P	G	R	V	A	K	I	G	D	F	G	.	.	M	A	R	D	I	Y	R	G	G	C	A	M	L	P	V	K	W	M
Template Known Secondary structure												T	T				S				G	G	G				S		S	S	T	T										.	.										G	G	G	S		G	G	G
Template Predicted Secondary structure																																										.	.
Template SS confidence
		1233	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.			.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290
		438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	P	E	A	F	M	E	G	I	F	T	S	K	T	D	T	W	S	F	G	V	L	L	W	E	I	F	S	L	G	Y	M	P	Y	P	S	K	S	N	Q	E	V	L	E	F	V	T	S	G	G	R	M	D	P	P	K	N	C	P	G
Template Known Secondary structure																													T	T	S			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		1297	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.
		498	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	V	Y	R	I	M	T	Q	C	W	Q	H	Q	P	E	D	R	P	N	F	A	I	I	L	E	R	I	E	Y	C
Template Known Secondary structure											T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1357	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D