Job Description P05480 Confidence 100.00% Date Tue Jul 30 13:01:21 BST 2013 Rank 290 Aligned Residues 253 % Identity 26% Template c2vagA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor Resolution 1.80 Å

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		269	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.			.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.
Predicted Secondary structure																														.	.
Query SS confidence																														.	.
Query Sequence		E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	.	.	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R
Query Conservation																														.	.
Alig confidence																														.	.
Template Conservation
Template Sequence		D	V	L	S	A	R	Y	E	I	V	D	T	L	G	E	G	A	F	G	K	V	V	E	C	I	D	H	K	A	G	G	R	H	V	A	V	K	I	V	K	N	V	D	R	Y	C	E	A	A	R	S	E	I	Q	V	L	E	H	L	N
Template Known Secondary structure					T	T	T											T	T									T	T	T	T	T										S	S
Template Predicted Secondary structure
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
		327	.	.	330							.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure						.	.	.	.	.	.
Query SS confidence						.	.	.	.	.	.
Query Sequence		H	E	K	L	.	.	.	.	.	.	V	Q	L	Y	A	V	V	S	E	E	P	I	Y	I	V	T	E	Y	M	N	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	S	A	Q	I	A	S
Query Conservation						.	.	.	.	.	.
Alig confidence						.	.	.	.	.	.
Template Conservation
Template Sequence		T	T	D	P	N	S	T	F	R	C	V	Q	M	L	E	W	F	E	H	H	G	H	I	C	I	V	F	E	L	L	G	L	S	T	Y	D	F	I	K	E	N	G	F	L	P	F	R	L	D	H	I	R	K	M	A	Y	Q	I	C	K
Template Known Secondary structure					T	T		T	T		B										T	T												B								T	T	T
Template Predicted Secondary structure
Template SS confidence
		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.
Query SS confidence																																																					.	.	.	.	.	.	.	.	.
Query Sequence		G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	.	.	.	.	.	.	.	.	.
Query Conservation																																																					.	.	.	.	.	.	.	.	.
Alig confidence																																																					.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	V	N	F	L	H	S	N	K	L	T	H	T	D	L	K	P	E	N	I	L	F	V	Q	S	D	Y	T	E	A	Y	N	K	R	D	E	R	T	L	I	N	P	D	I	K	V	V	D	F	G	S	A	T	Y	D	D	E	H	H	S
Template Known Secondary structure									T	T								G	G	G				S																	S										S	S				T	T	S
Template Predicted Secondary structure
Template SS confidence
		275	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
			432	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure		.																																																							.	.	.	.	.
Query SS confidence		.																																																							.	.	.	.	.
Query Sequence		.	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	.	.	.	.	.
Query Conservation		.																																																							.	.	.	.	.
Alig confidence		.																																			.																				.	.	.	.	.
Template Conservation																																					.
Template Sequence		T	L	V	R	H	Y	R	A	P	E	V	I	L	A	L	G	W	S	Q	P	C	D	V	W	S	I	G	C	I	L	I	E	Y	Y	L	.	G	F	T	V	F	P	T	H	D	S	K	E	H	L	A	M	M	E	R	I	L	G	P	L
Template Known Secondary structure		S					S							T	T	S			S	T																	.	S	S		S				S															S
Template Predicted Secondary structure																																					.
Template SS confidence
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
																																								486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		P	K	H	M	I	Q	K	T	R	K	R	K	Y	F	H	H	D	R	L	D	W	D	E	H	S	S	A	G	R	Y	V	S	R	A	C	K	P	L	K	E	F	M	L	S	Q	D	V	E	H	E	R	L	F	D	L	I	Q	K	M	L
Template Known Secondary structure										S		G	G	G			T	T						T	T	S													G	G	G	G		S			S														T
Template Predicted Secondary structure
Template SS confidence
		399	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.
		508	.	510	.	.	.	.	.	.	.	.	.	520	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	Y	D	P	A	K	R	I	T	L	R	E	A	L	K
Template Known Secondary structure			S	S	T	T	T	S							T	T
Template Predicted Secondary structure
Template SS confidence
		459	460	.	.	.	.	.	.	.	.	.	470	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D