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Job DescriptionP05480
Confidence100.00%DateTue Jul 30 13:01:21 BST 2013
Rank5Aligned Residues431
% Identity62%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å
Model Dimensions (Å)X:73.865 Y:71.608 Z:52.580

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   87..90.........100.........110.........120.........130.........140......
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Query Sequence  TFVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVA
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Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVLEESGE. . . . . . . WWKARSLATRKEGYIPSNYVA
Template Known Secondary structure  SS
B


SSSB

B
TT
TT.......TTT

GGG
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   61........70.........80.........90.. .......100.........110...
 
   147..150.........160.........170.........180.........190.........200......
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Query Sequence  PSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLN
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Template Sequence  RVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDT
Template Known Secondary structure  TTSGGGSTTTT

TSTT

TT

SSSTT
TTT
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   114.....120.........130.........140.........150.........160.........170...
 
   207..210.........220.........230.........240.........250.........260......
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Query Sequence  VKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKD
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Template Sequence  VKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQ. KPWEKD
Template Known Secondary structure  B

STT
SSTTSSSTTSS
SS
SS


SB






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TT
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   174.....180.........190.........200.........210.........220...... ...230..
 
   267..270.........280.........290.........300.........310.........320......
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Query Sequence  AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLR
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Template Sequence  AWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQ
Template Known Secondary structure 
SB

GGGTTTTT


SS
T

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   233......240.........250.........260.........270.........280.........290..
 
   327..330.........340.........350.........360.........370.........380......
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Query Sequence  HEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVE
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Template Sequence  HDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIE
Template Known Secondary structure 
TTB


SSS


TT
BSTTGGG

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   293......300.........310.........320.........330.........340.........350..
 
   387..390.........400.........410.........420.........430.........440......
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Query Sequence  RMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR
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Template Sequence  QRNYIHRDLRAANILVSASLVCKIADFGLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGS
Template Known Secondary structure  TT


S

SGGG
TT



TTGGG.............T

GGGS


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   353......360.........370.........380... ......390.........
 
   447..450.........460.........470.........480.........490.........500......
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Query Sequence  FTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQC
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Template Sequence  FTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRC
Template Known Secondary structure 

TTT

SSTT

TT





TT

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   413......420.........430.........440.........450.........460.........470..
 
   507..510.........520.........530........
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Query Sequence  WRKEPEERPTFEYLQAFLEDYFTSTEPQYQPG
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Template Sequence  WKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure  T
SSGGGS

TTTS
GGG




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   473......480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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