|   |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | S | W | E | S | Y | L | E | E | Q | K | A | V | T | A | P | V | S | L | F | Q | D | S | Q | A | V | T | H | N | K | N | G | F | K | L | G | M | K | L | E | G | I | D | P | Q | H | P | S | M | Y | F | I | L | T | V | A | E | V | C | G |
| Query Conservation |   |
|   |
|   |   |
|
|   |
|
|   |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |
|
|
|
|
|
|   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|   |
|
| Template Sequence |   |
W | S | W | E | S | Y | L | E | E | Q | K | A | I | T | A | P | V | S | L | F | Q | D | S | Q | A | V | T | H | N | K | N | G | F | K | L | G | X | K | L | E | G | I | D | P | Q | H | P | S | X | Y | F | I | L | T | V | A | E | V | C | G |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  | T |
|
| B |
|
| G | G | G | S |
|  |  |  |  |
|
| S | S |
|
|
|
|
| T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
|   |
|   |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | R | L | R | L | H | F | D | G | Y | S | E | C | H | D | F | W | V | N | A | N | S | P | D | I | H | P | A | G | W | F | E | K | T | G | H | K | L | Q | L | P | K | G | Y | K | E | E | E | F | S | W | S | Q | Y | L | R | S | T | K | A |
| Query Conservation |   |
  |
|
|   |
|
|   |
|
|   |   |   |   |   |
|
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|   |   |
|
|   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
| Template Sequence |   |
Y | R | L | R | L | H | F | D | G | Y | S | E | C | H | D | F | W | V | N | A | N | S | P | D | I | H | P | A | G | W | F | E | K | T | G | H | K | L | Q | P | P | K | G | Y | K | E | E | E | F | S | W | S | Q | Y | L | R | S | T | R | A |
| Template Known Secondary structure |   |
T |  |  |  |  |  |  | T | T | S |
| G | G | G |
|  |  |  |  | T | T |
| T | T |  |  |
| T | T |  |  |  |  |  | T |
|
|  |  |
| S | T | T |
|
| G | G | G |
|
|  |  |  |  |  |  |  |  | T |
|
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
|   |
|   |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | A | A | P | K | H | L | F | V | S | Q | S | H | S | T | P | P | V | G | F | Q | V | G | M | K | L | E | A | V | D | R | M | N | P | S | L | V | C | V | A | S | V | T | D | V | V | D | S | R | F | L | V | H | F | D | D | W | G | D | T |
| Query Conservation |   |
  |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
| Template Sequence |   |
Q | A | A | P | K | H | L | F | V | S | Q | S | H | S | P | P | P | L | G | F | Q | V | G | X | K | L | E | A | V | D | R | X | N | P | S | L | V | C | V | A | S | V | T | D | V | V | D | S | R | F | L | V | H | F | D | N | W | D | D | T |
| Template Known Secondary structure |   |
| B |
|
| G | G | G |
| S |
| S | S |
| S |
|
|
| T | T |
|
| T | T |
|  |  |  |  |  |
| T | T | S | T | T |
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  | T | T | S |
| G | G |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
|   |
|   |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | D | Y | W | C | D | P | S | S | P | Y | I | H | P | V | G | W | C | Q | K | Q | G | K | P | L | T | P | P | Q | D | Y | P | D | P | D | S | F | C | W | E | K | Y | L | E | E | T | G | T | S | A | V | P | N | W | A | F | K | V | R | P |
| Query Conservation |   |
  |
|
|
|
|
|   |
|
|   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|
|   |
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|   |   |   |
|
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |
|   |   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|   |   |   |
|
|   |   |   |
| Template Sequence |   |
Y | D | Y | W | C | D | P | S | S | P | Y | I | H | P | V | G | W | C | Q | K | Q | G | K | P | L | T | P | P | Q | D | Y | P | D | P | D | N | F | C | W | E | K | Y | L | E | E | T | G | A | S | A | V | P | T | W | A | F | K | V | R | P |
| Template Known Secondary structure |   |
G |
|  |  |  |
| T | T |
| T | T |  |  |
| T | T |  |  |  |  |  | T |
|
|
| B |
|
| T | T |
| S | S | G | G | G |
|
|  |  |  |  |  |  |  | T | T |
|
| B |
|
| G | G | G |
|
|
|
|
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |
|
|  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
|   |
|   |   |
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | H | S | F | L | V | N | M | K | L | E | A | V | D | R | R | N | P | A | L | I | R | V | A | S | V | E | D | V | E | D | H | R | I | K | L | H | F | D | G | W | S | H | N | Y | D | F | W | I | D | A | D | H | P | D | I | H | P | A | G |
| Query Conservation |   |
  |   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |
|
|
|
|   |   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|   |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|   |
|
|
|
| Template Sequence |   |
P | H | S | F | L | V | N | X | K | L | E | A | V | D | R | R | N | P | A | L | I | R | V | A | S | V | E | D | V | E | D | H | R | I | K | I | H | F | D | G | W | S | H | G | Y | D | F | W | I | D | A | D | H | P | D | I | H | P | A | G |
| Template Known Secondary structure |   |
|
|
|
|
| T | T |
|  |  |  |  |  |
| T | T | S | T | T |
|  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  | T | T | S |
| G | G | G |
|  |  |  |  | T | T |
| T | T |  |  |
| T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
446 | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
|   |
|   |   |
580 | . | . | . | . | . | . | . | . | . | 590 | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | C | S | K | T | G | H | P | L | E | P | P | L |
| Query Conservation |   |
|
|   |   |   |
|   |
|
|
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |
|   |   |
|   |
|
|   |
| Template Sequence |   |
W | C | S | K | T | G | H | P | L | Q | P | P | L |
| Template Known Secondary structure |   |
 |  |  |  |  | T |
|
|
| B |
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . |
|   |