Job Description O08908 Confidence 100.00% Date Wed Jul 10 14:15:46 BST 2013 Rank 2 Aligned Residues 255 % Identity 27% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:64.287 Y:53.964 Z:47.244

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		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.			340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
Predicted Secondary structure																								.	.
Query SS confidence																								.	.
Query Sequence		S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	R	L	R	.	.	D	T	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	V	F
Query Conservation																								.	.
Alig confidence																								.	.																.
Template Conservation																																									.
Template Sequence		S	A	N	H	L	P	F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	.	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E
Template Known Secondary structure				T	T		T	T	B		B	S													T	T			T	T								T	T	S	.	S	S									T	T
Template Predicted Secondary structure																																									.
Template SS confidence
		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.		.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.
		376	.		.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
Predicted Secondary structure				.
Query SS confidence				.
Query Sequence		H	R	.	D	G	H	Y	G	F	S	E	P	L	T	F	C	S	V	V	E	L	I	S	H	Y	R	H	E	S	L	A	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S	K	Y	Q	Q	D	Q	V	V	K	E	D	S	I	E
Query Conservation				.
Alig confidence				.																											.	.	.	.	.																				.
Template Conservation																															.	.	.	.	.																				.
Template Sequence		R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H	Y	H	S	Q	E	S	.	.	.	.	.	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	.	K	T	G	P	F	E
Template Known Secondary structure				T	T	S					T	T				B	S	S								T	T	T			.	.	.	.	.	S	S	S	S	S										T	T	B			.	B		S
Template Predicted Secondary structure																															.	.	.	.	.																				.
Template SS confidence
		68	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.						.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.		.	.	.	.	120	.
		435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	G	A	Q	L	K	V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K
Query Conservation
Alig confidence																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	L	K	E	N	L	I	R	E	Y	V	K	Q	T	W	N	L	Q	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
		495	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	S	K	E	Y	L	E	R	F	R	R	E	G	N	E	K	E	M	Q	R	I	L	L	N	S	E	R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	A	L	E	Q	A	I	I	S	Q	K	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.																			T	T	S		G	G	G	S	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
		555	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	S	L	K	P	D	L	M	Q	L	R	K	I	R	D	Q	Y	L	V	W	L	T	Q	K	G	A	R	Q	R	K	I	N	E	W	L	G	I	K	N	E	T	E	D	Q	Y	S	L	M	E	D	E	D	A	L	P	H	H	E	E	R
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		615	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630			.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.
Predicted Secondary structure																		.	.
Query SS confidence																		.	.
Query Sequence		T	W	Y	V	G	K	I	N	R	T	Q	A	E	E	M	L	.	.	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G
Query Conservation																		.	.
Alig confidence		.																.	.
Template Conservation		.
Template Sequence		.	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L
Template Known Secondary structure		.	T	B			S												S	S	S			T	T									T	T	T									T	T											T	T	S
Template Predicted Secondary structure		.
Template SS confidence
			168	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
		673	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	A	E	P	Y	N	L	Y	G	S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P	G	P	G	P	P	S
Query Conservation
Alig confidence																								.	.	.	.	.
Template Conservation																								.	.	.	.	.
Template Sequence		S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	.	.	.	.	.	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A
Template Known Secondary structure			S	T	T				B	S	S									T	T	B		.	.	.	.	.	T	T	S	S	S				S	B				S				T	T
Template Predicted Secondary structure																								.	.	.	.	.
Template SS confidence
		227	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.						.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D