Job Description O08908 Confidence 100.00% Date Wed Jul 10 14:15:46 BST 2013 Rank 10 Aligned Residues 234 % Identity 77% Template c3hizB_ PDB info PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha Resolution 3.30 Å Model Dimensions (Å) X:114.102 Y:46.430 Z:74.584

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	R	L	R	D	T	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	V	F	H	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	L	Q	N	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	D	T	A	D	G	T	F	L	V	R	D	A	S	T	K	M	H	G	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	F	H	R
Template Known Secondary structure				S	S		S	S				S										S	S	S			T	T								S	S		S	S										S	S	S							B		G
Template Predicted Secondary structure
Template SS confidence
		327	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	G	H	Y	G	F	S	E	P	L	T	F	C	S	V	V	E	L	I	S	H	Y	R	H	E	S	L	A	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S	K	Y	Q	Q	D	Q	V	V	K	E	D	S	I	E	A	V	G
Query Conservation
Alig confidence																												.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																												.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	G	K	Y	G	F	S	D	P	L	T	F	S	S	V	V	E	L	I	N	H	Y	L	A	Q	Y	.	.	.	.	N	P	K	L	D	V	K	L	L	Y	P	V	S	K	Y	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		G	G			B	S	S	S	S					S	S						T				S	S	.	.	.	.		T	T			S											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																												.	.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.					.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.
		438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Q	L	K	V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	K	L	H	E	Y	N	T	Q	F	Q	E	K	S	R	E	Y	D	R	L	Y	E	E	Y	T	R	T	S	Q	E	I	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	C	Q	T	Q	E	R	Y	S	K
Template Known Secondary structure		.		S		T	T	T																																																					T
Template Predicted Secondary structure		.
Template SS confidence
			448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.
		498	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	Y	L	E	R	F	R	R	E	G	N	E	K	E	M	Q	R	I	L	L	N	S	E	R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	Y	I	E	K	F	K	R	E	G	N	E	K	E	I	Q	R	I	M	H	N	Y	D	K	L	K	S	R	I	S	E	I	I	D	S	R	R	R	L	E	E	D	L	K	K	Q	A	A	E	Y	R	E	I	D	K	R	M	N	S	I
Template Known Secondary structure		T	T	T	T	T	T	T	T	S	S			S	T	T
Template Predicted Secondary structure
Template SS confidence
		507	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.
		558	.	560	.	.	.	.	.	.	.	.	.	570
Predicted Secondary structure
Query SS confidence
Query Sequence		K	P	D	L	M	Q	L	R	K	I	R	D	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	P	D	L	I	Q	L	R	K	T	R	D	Q
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		567	.	.	570	.	.	.	.	.	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D