Job Description O08908 Confidence 100.00% Date Wed Jul 10 14:15:46 BST 2013 Rank 4 Aligned Residues 197 % Identity 35% Template c2b3oA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1 Resolution 2.80 Å Model Dimensions (Å) X:59.924 Y:58.859 Z:33.108

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		324	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.		.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure																				.
Query SS confidence																				.
Query Sequence		W	Y	W	G	D	I	S	R	E	E	V	N	E	R	L	R	D	T	.	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	V	F	H	R	D	G	H	Y	G
Query Conservation																				.
Alig confidence																				.														.
Template Conservation																																		.
Template Sequence		W	F	H	R	D	L	S	G	L	D	A	E	T	L	L	K	G	R	G	V	H	G	S	F	L	A	R	P	S	R	K	N	.	Q	G	D	F	S	L	S	V	R	V	G	D	Q	V	T	H	I	R	I	Q	N	S	G	D	F	Y	D
Template Known Secondary structure		T	B		S	S																T	T								S	S	S	.	S	S									T	T										S	S	S
Template Predicted Secondary structure																																		.
Template SS confidence
		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.		.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.		.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.
Predicted Secondary structure																									.
Query SS confidence																									.
Query Sequence		F	S	E	P	L	T	F	C	S	V	V	E	L	I	S	H	Y	R	H	E	S	L	A	.	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S	K	Y	Q	Q	D	Q	V	V	K	E	D	S	I	E	A	V	G	A	Q	L	K
Query Conservation																									.
Alig confidence																									.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	Y	G	G	E	K	F	A	T	L	T	E	L	V	E	Y	Y	T	Q	Q	Q	G	V	L	Q	D	R	D	G	T	I	I	H	L	K	Y	P	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure			T	T	S				S											T	T		S		B			S	S	S			B							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100
		442	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K	E	Y	L	E
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		502	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	F	R	R	E	G	N	E	K	E	M	Q	R	I	L	L	N	S	E	R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L	K	P	D	L
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		562	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	Q	L	R	K	I	R	D	Q	Y	L	V	W	L	T	Q	K	G	A	R	Q	R	K	I	N	E	W	L	G	I	K	N	E	T	E	D	Q	Y	S	L	M	E	D	E	D	A	L	P	H	H	E	E	R	T	W	Y	V	G	K	I
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	C	S	D	P	T	S	E	R	W	Y	H	G	H	M
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					G	G	G		T	T	B		T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																															101	.	.	.	.	.	.	.	.	110	.	.	.	.	.
		622	.	.	.	.	.	.	.	630	.	.	.	.		.	.	.	.	.	640	.	.	.		.	.	.	.	.	.	650	.	.	.	.	.						.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.
Predicted Secondary structure															.										.													.	.	.	.	.
Query SS confidence															.										.													.	.	.	.	.
Query Sequence		N	R	T	Q	A	E	E	M	L	S	G	K	R	.	D	G	T	F	L	I	R	E	S	.	S	Q	R	G	C	Y	A	C	S	V	V	V	.	.	.	.	.	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A
Query Conservation															.										.													.	.	.	.	.
Alig confidence															.										.													.	.	.	.	.										.
Template Conservation																																																				.
Template Sequence		S	G	G	Q	A	E	T	L	L	Q	A	K	G	E	P	W	T	F	L	V	R	E	S	L	S	Q	P	G	D	F	V	L	S	V	L	S	D	Q	P	K	S	P	L	R	V	T	H	I	K	V	.	M	C	E	G	G	R	Y	T	V
Template Known Secondary structure																T	T								S	S	S	T	T																							.	B			T	T	S	B	B	S
Template Predicted Secondary structure																																																				.
Template SS confidence
		116	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.		.	.	.	.	170	.	.	.	.
		675	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710
Predicted Secondary structure
Query SS confidence
Query Sequence		E	P	Y	N	L	Y	G	S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V
Query Conservation
Alig confidence																											.
Template Conservation																											.
Template Sequence		G	G	L	E	T	F	D	S	L	T	D	L	V	E	H	F	K	K	T	G	I	E	E	A	S	.	G	A	F	V	Y	L	R	Q	P	Y
Template Known Secondary structure		S	S	S			B	S	S																S	S	.	S
Template Predicted Secondary structure																											.
Template SS confidence
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.		.	.	.	.	.	.	210	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D