Job Description O08908 Confidence 99.92% Date Wed Jul 10 14:15:46 BST 2013 Rank 34 Aligned Residues 152 % Identity 53% Template c1x27F_ PDB info PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas Resolution 2.70 Å

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		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	A	V	Y	P	F	R	R	E	R	P	E	D	L	E	L	L	P	G	D	L	L	V	V	S	R	V	A	L	Q	A	L	G	V	A	D	G	G	E	R	C	P	H	N	V	G	W	M	P	G	F	N	E	R	T	R	Q	R	G
Query Conservation
Alig confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	I	A	L	H	S	Y	E	P	S	H	D	G	D	L	G	F	E	K	G	E	Q	L	R	I	L	E	Q	S	G	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	W	K	A	Q	S	L	T	T	G	Q	E	G
Template Known Secondary structure					S	S		B				S	T	T	B			B		T	T									B	T	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							S	S	S
Template Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		66	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.																	.	.	.	100	.	.	.	.	.	.	.	.	.
		69	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	F	P	G	T	Y	V	E	F	L	G	P	V	A	L	A	R	P	G	P	R	P	R	G	P	R	P	L	P	A	R	P	L	D	G	S	S	E	S	G	H	I	L	P	D	L	A	E	Q	F	S	P	P	D	P	A	P	P	I	L
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	I	P	F	N	F	V	A	K	A	N	S	L	E	P	E	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure					G	G	G					S		S	T	T	S	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	K	L	V	E	A	I	E	Q	A	E	L	D	S	E	C	Y	S	K	P	E	L	P	A	T	R	T	D	W	S	L	S	D	L	E	Q	W	D	R	T	A	L	Y	D	A	V	K	G	F	L	L	A	L	P	A	A	V	V	T	P
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	A	A	E	A	Y	R	A	L	R	E	V	A	G	P	V	G	L	V	L	E	P	P	T	L	P	L	H	Q	A	L	T	L	R	F	L	L	Q	H	L	G	R	V	A	R	R	A	P	S	P	D	T	A	V	H	A	L	A	S
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	F	G	P	L	L	L	R	I	P	P	S	G	G	E	G	D	G	S	E	P	V	P	D	F	P	V	L	L	L	E	R	L	V	Q	E	H	V	E	E	Q	D	A	A	P	P	A	L	P	P	K	P	S	K	A	K	P	A	P	T
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.			.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure																																.	.
Query SS confidence																																.	.
Query Sequence		A	L	A	N	G	G	S	P	P	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	R	L	.	.	R	D	T	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G
Query Conservation																																.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.																	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	F	F	K	N	L	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	T	H	G	S	F	L	I	R	E	S	E	S	T	.	A	G	S	F	S	L	S	V	R	D	F
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	B		S	S											T	S	S	S			T	T								S	S	S	.	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template SS confidence
																	127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.		160	.	.	.	.	.	.	.	.	.	170
		367	.	.	370	.	.	.	.	.	.	.							.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Predicted Secondary structure													.	.	.	.	.	.
Query SS confidence													.	.	.	.	.	.
Query Sequence		G	N	N	K	L	I	K	V	F	H	R	.	.	.	.	.	.	D	G	H	Y	G	F	S	E	P	L	T	F	C	S	V	V	E	L	I	S	H	Y	R	H	E	S	L	A	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S
Query Conservation													.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.																											.	.	.	.	.
Template Conservation																																													.	.	.	.	.
Template Sequence		D	Q	N	Q	G	E	V	V	K	H	Y	K	I	R	N	L	D	N	G	G	F	Y	I	S	P	R	I	T	F	P	G	L	H	E	L	V	R	H	Y	T	N	A	S	.	.	.	.	.	D	G	L	C	T	R	L	S	R	P	C	Q
Template Known Secondary structure			S	S	S													T	T	S				S	S	T	T			B	S	S													.	.	.	.	.	S	S	S	S	S
Template Predicted Secondary structure																																													.	.	.	.	.
Template SS confidence
		171	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.						.	.	.	.	.	.	220	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D