Job Description O08908 Confidence 99.94% Date Wed Jul 10 14:15:46 BST 2013 Rank 31 Aligned Residues 161 % Identity 34% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å

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		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	A	V	Y	P	F	R	R	E	R	P	E	D	L	E	L	L	P	G	D	L	L	V	V	S	R	V	A	L	Q	A	L	G	V	A	D	G	G	E	R	C	P	H	N	V	G	W	M	P	G	F	N	E	R	T	R	Q	R	G
Query Conservation
Alig confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.								.	.
Template Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.	.								.	.
Template Sequence		F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	G	E	W	C	E	A	.	.	Q	T	K	N	G	Q	G
Template Known Secondary structure					S	S		B				S	T	T	B			B		T	T										T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	S	S					.	.			S	S
Template Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.	.								.	.
Template SS confidence
		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.															.	.	.	.	.	120	.			.	.	.	.	.	.	.
		69	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	F	P	G	T	Y	V	E	F	L	G	P	V	A	L	A	R	P	G	P	R	P	R	G	P	R	P	L	P	A	R	P	L	D	G	S	S	E	S	G	H	I	L	P	D	L	A	E	Q	F	S	P	P	D	P	A	P	P	I	L
Query Conservation
Alig confidence										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		W	V	P	S	N	Y	I	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure					G	G	G			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		129	130	.	.	.	.	.	.
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	K	L	V	E	A	I	E	Q	A	E	L	D	S	E	C	Y	S	K	P	E	L	P	A	T	R	T	D	W	S	L	S	D	L	E	Q	W	D	R	T	A	L	Y	D	A	V	K	G	F	L	L	A	L	P	A	A	V	V	T	P
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	A	A	E	A	Y	R	A	L	R	E	V	A	G	P	V	G	L	V	L	E	P	P	T	L	P	L	H	Q	A	L	T	L	R	F	L	L	Q	H	L	G	R	V	A	R	R	A	P	S	P	D	T	A	V	H	A	L	A	S
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	F	G	P	L	L	L	R	I	P	P	S	G	G	E	G	D	G	S	E	P	V	P	D	F	P	V	L	L	L	E	R	L	V	Q	E	H	V	E	E	Q	D	A	A	P	P	A	L	P	P	K	P	S	K	A	K	P	A	P	T
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	A	N	G	G	S	P	P	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	R	L	R	D	T	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G	G	N
Query Conservation
Alig confidence		.	.	.	.	.	.																																									.
Template Conservation		.	.	.	.	.	.																																									.
Template Sequence		.	.	.	.	.	.	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	.	P	G	Q	R	S	I	S	L	R	Y	E	G	R
Template Known Secondary structure		.	.	.	.	.	.		S	S	S	G	G	G	S	T	T														G	G	G			T	T								S	S	S	.	T	T									T	T
Template Predicted Secondary structure		.	.	.	.	.	.																																									.
Template SS confidence
								137	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.		.	.	.	180	.	.	.	.	.	.	.	.	.
		369	370	.	.	.	.	.	.	.		.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.
Predicted Secondary structure											.
Query SS confidence											.
Query Sequence		N	K	L	I	K	V	F	H	R	.	D	G	H	Y	G	F	S	E	P	L	T	F	C	S	V	V	E	L	I	S	H	Y	R	H	E	S	L	A	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S	K	Y	Q	Q	D	Q	V
Query Conservation											.
Alig confidence											.																											.	.	.	.	.
Template Conservation																																						.	.	.	.	.
Template Sequence		V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	.	.	.	.	.	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V
Template Known Secondary structure											T	T	S				S	S	T	T	S		B	S	S									T	T			.	.	.	.	.	T	T	S	S	S										S
Template Predicted Secondary structure																																						.	.	.	.	.
Template SS confidence
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.						.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
		428	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	G
Template Known Secondary structure		S	S
Template Predicted Secondary structure
Template SS confidence
		245	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D