Job Description A2A432 Confidence 100.00% Date Tue Jul 30 13:09:03 BST 2013 Rank 1 Aligned Residues 719 % Identity 85% Template c2hyeC_ PDB info PDB header:protein binding Chain: C: PDB Molecule:cullin-4a; PDBTitle: crystal structure of the ddb1-cul4a-rbx1-sv5v complex Resolution 3.10 Å Model Dimensions (Å) X:79.188 Y:165.962 Z:76.731

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		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	K	L	V	I	K	N	F	K	D	K	P	K	L	P	E	N	Y	T	D	E	T	W	Q	K	L	K	E	A	V	E	A	I	Q	N	S	T	S	I	K	Y	N	L	E	E	L	Y	Q	A	V	E	N	L	C	S	H	K	I	S	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	K	L	V	I	K	N	F	R	D	R	P	R	L	P	D	N	Y	T	Q	D	T	W	R	K	L	H	E	A	V	R	A	V	Q	S	S	T	S	I	R	Y	N	L	E	E	L	Y	Q	A	V	E	N	L	C	S	H	K	V	S	P
Template Known Secondary structure							T	T					S		S	S			T	T	T	T											T	T	S	T	T				S	S															T	T	T
Template Predicted Secondary structure
Template SS confidence
		41	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100
		312	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	L	Y	K	Q	L	R	Q	I	C	E	D	H	I	K	A	Q	I	H	Q	F	R	E	D	S	L	D	S	V	L	F	L	K	K	I	D	R	C	W	Q	N	H	C	R	Q	M	I	M	I	R	S	I	F	L	F	L	D	R	T	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	L	Y	K	Q	L	R	Q	A	C	E	D	H	V	Q	A	Q	I	L	P	F	R	E	D	S	L	D	S	V	L	F	L	K	K	I	N	T	C	W	Q	D	H	C	R	Q	M	I	M	I	R	S	I	F	L	F	L	D	R	T	Y
Template Known Secondary structure																							T	S					T	T																								T					T	T	T
Template Predicted Secondary structure
Template SS confidence
		101	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
		372	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	Q	N	S	M	L	P	S	I	W	D	M	G	L	E	L	F	R	A	H	I	I	S	D	Q	K	V	Q	T	K	T	I	D	G	I	L	L	L	I	E	R	E	R	N	G	E	A	I	D	R	S	L	L	R	S	L	L	S	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	L	Q	N	S	T	L	P	S	I	W	D	M	G	L	E	L	F	R	T	H	I	I	S	D	K	M	V	Q	S	K	T	I	D	G	I	L	L	L	I	E	R	E	R	S	G	E	A	V	D	R	S	L	L	R	S	L	L	G	M
Template Known Secondary structure		T	T	S		S	S	S														T	T	T	S	S	S	T	T														T	T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
		432	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	S	D	L	Q	I	Y	Q	D	S	F	E	Q	Q	F	L	Q	E	T	N	R	L	Y	A	A	E	G	Q	K	L	M	Q	E	R	E	V	P	E	Y	L	H	H	V	N	K	R	L	E	E	E	A	D	R	L	I	T	Y	L	D	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	S	D	L	Q	V	Y	K	D	S	F	E	L	K	F	L	E	E	T	N	C	L	Y	A	A	E	G	Q	R	L	M	Q	E	R	E	V	P	E	Y	L	N	H	V	S	K	R	L	E	E	E	G	D	R	V	I	T	Y	L	D	H
Template Known Secondary structure					T	T						T																							S																T					T	T	T	S		T
Template Predicted Secondary structure
Template SS confidence
		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
		492	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	T	Q	K	S	L	I	A	S	V	E	K	Q	L	L	G	E	H	L	T	A	I	L	Q	K	G	L	N	S	L	L	D	E	N	R	I	Q	D	L	S	L	L	Y	Q	L	F	S	R	V	R	G	G	V	Q	V	L	L	Q	Q	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	T	Q	K	P	L	I	A	C	V	E	K	Q	L	L	G	E	H	L	T	A	I	L	Q	K	G	L	D	H	L	L	D	E	N	R	V	P	D	L	A	Q	M	Y	Q	L	F	S	R	V	R	G	G	Q	Q	A	L	L	Q	H	W
Template Known Secondary structure		T	T													T	T	T		S						T	T						T	T	T															S	T	T
Template Predicted Secondary structure
Template SS confidence
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340
		552	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	Y	I	K	A	F	G	S	T	I	V	I	N	P	E	K	D	K	T	M	V	Q	E	L	L	D	F	K	D	K	V	D	H	I	I	D	T	C	F	L	K	N	E	K	F	I	N	A	M	K	E	A	F	E	T	F	I	N	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	E	Y	I	K	T	F	G	T	A	I	V	I	N	P	E	K	D	K	D	M	V	Q	D	L	L	D	F	K	D	K	V	D	H	V	I	E	V	C	F	Q	K	N	E	R	F	V	N	L	M	K	E	S	F	E	T	F	I	N	K
Template Known Secondary structure														S		G	G	G	T	T	T																		T	T	T	T	T																	T	T
Template Predicted Secondary structure
Template SS confidence
		341	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
		612	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	N	K	P	A	E	L	I	A	K	Y	V	D	S	K	L	R	A	G	N	K	E	A	T	D	E	E	L	E	K	M	L	D	K	I	M	I	I	F	R	F	I	Y	G	K	D	V	F	E	A	F	Y	K	K	D	L	A	K	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	P	N	K	P	A	E	L	I	A	K	H	V	D	S	K	L	R	A	G	N	K	E	A	T	D	E	E	L	E	R	T	L	D	K	I	M	I	L	F	R	F	I	H	G	K	D	V	F	E	A	F	Y	K	K	D	L	A	K	R
Template Known Secondary structure		S		S															S	S		G	G	G			S	T	T													T	T		S
Template Predicted Secondary structure
Template SS confidence
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	V	G	K	S	A	S	V	D	A	E	K	S	M	L	S	K	L	K	H	E	C	G	A	A	F	T	S	K	L	E	G	M	F	K	D	M	E	L	S	K	D	I	M	I	Q	F	K	Q	Y	M	Q	N	Q	N	V	P	G	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	V	G	K	S	A	S	V	D	A	E	K	S	M	L	S	K	L	K	H	E	C	G	A	A	F	T	S	K	L	E	G	M	F	K	D	M	E	L	S	K	D	I	M	V	H	F	K	Q	H	M	Q	N	Q	S	D	S	G	P
Template Known Secondary structure				S	S			S														T	T	T		T	T	T	T																										T	T
Template Predicted Secondary structure
Template SS confidence
		461	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520
		732	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	L	T	V	N	I	L	T	M	G	Y	W	P	T	Y	V	P	M	E	V	H	L	P	P	E	M	V	K	L	Q	E	I	F	K	T	F	Y	L	G	K	H	S	G	R	K	L	Q	W	Q	S	T	L	G	H	C	V	L	K	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	D	L	T	V	N	I	L	T	M	G	Y	W	P	T	Y	T	P	M	E	V	H	L	T	P	E	M	I	K	L	Q	E	V	F	K	A	F	Y	L	G	K	H	S	G	R	K	L	Q	W	Q	T	T	L	G	H	A	V	L	K	A
Template Known Secondary structure											T	T	T	S																											T	T	S		S							G	G	G
Template Predicted Secondary structure
Template SS confidence
		521	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580
		792	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	F	K	E	G	K	K	E	L	Q	V	S	L	F	Q	T	M	V	L	L	M	F	N	E	G	E	E	F	S	L	E	E	I	K	H	A	T	G	I	E	D	G	E	L	R	R	T	L	Q	S	L	A	C	G	K	A	R	V	L	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	F	K	E	G	K	K	E	F	Q	V	S	L	F	Q	T	L	V	L	L	M	F	N	E	G	D	G	F	S	F	E	E	I	K	M	A	T	G	I	E	D	S	E	L	R	R	T	L	Q	S	L	A	C	G	K	A	R	V	L	I
Template Known Secondary structure				S	S																		T	T	S													T													T	T	T	T	T	T	T		S
Template Predicted Secondary structure
Template SS confidence
		581	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640
		852	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	N	P	K	G	K	D	I	E	D	G	D	K	F	I	C	N	D	D	F	K	H	K	L	F	R	I	K	I	N	Q	I	Q	M	K	E	T	V	E	E	Q	A	S	T	T	E	R	V	F	Q	D	R	Q	Y	Q	I	D	A	A	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	S	P	K	G	K	E	V	E	D	G	D	K	F	I	F	N	G	E	F	K	H	K	L	F	R	I	K	I	N	Q	I	Q	M	K	E	T	V	E	E	Q	V	S	T	T	E	R	V	F	Q	D	R	Q	Y	Q	I	D	A	A	I
Template Known Secondary structure			T	T		S	S	S			S	S												S		S	S				G	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		641	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
		912	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970
Predicted Secondary structure
Query SS confidence
Query Sequence		V	R	I	M	K	M	R	K	T	L	S	H	N	L	L	V	S	E	V	Y	N	Q	L	K	F	P	V	K	P	A	D	L	K	K	R	I	E	S	L	I	D	R	D	Y	M	E	R	D	K	E	N	P	N	Q	Y	N	Y	I	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	R	I	M	K	M	R	K	T	L	G	H	N	L	L	V	S	E	L	Y	N	Q	L	K	F	P	V	K	P	G	D	L	K	K	R	I	E	S	L	I	D	R	D	Y	M	E	R	D	K	D	N	P	N	Q	Y	H	Y	V	A
Template Known Secondary structure								S	S				T											S	S	S																	T	T	S		B			S	S		T	T
Template Predicted Secondary structure
Template SS confidence
		701	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.