|   |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
. | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| Query Sequence |   |
I | D | R | N | S | I | A | L | E | R | R | L | G | T | G | C | F | G | D | V | W | L | G | T | W | N | . |
C | S | T | K | V | A | V | K | T | L | K | P | G | T | M | S | P | K | A | F | L | E | E | A | Q | I | M | K | L | L | . |
R | H |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| . |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| Template Conservation |   |
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
| Template Sequence |   |
L | G | L | Q | D | F | D | L | L | R | V | I | G | R | G | S | Y | A | K | V | L | L | V | R | L | K | K | T | D | R | I | Y | A | M | R | V | V | K | K | E | L | V | N | I | D | W | V | Q | T | E | K | H | V | F | E | Q | A | S | N | H |
| Template Known Secondary structure |   |
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  | G | G | G | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
|   |
|   |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | |
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | K | L | V | Q | L | Y | A | V | V | S | E | . |
E | P | I | Y | I | V | T | E | F | M | C | Y | G | S | L | L | D | F | L | K | D | R | E | G | Q | N | L | M | L | P | H | L | V | D | M | A | A | Q | V | A | E | G | M | A | Y | M | E |
| Query Conservation |   |
  |
|
|
|   |   |   |
|   |   |   |   | . |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | F | L | V | G | L | H | S | C | F | Q | T | E | S | R | L | F | F | V | I | E | Y | V | N | G | G | D | L | M | F | H | M | Q | R | Q | R | . |
. |
K | L | P | E | E | H | A | R | F | Y | S | A | E | I | S | L | A | L | N | Y | L | H |
| Template Known Secondary structure |   |
T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  | S | . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | |
|
. | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
|   |
|   |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | M | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | G | E | Y | L | I | C | K | I | A | D | F | G | L | A | R | L | I | E | D | N | E | Y | N | P | Q | Q | G | T | K | F | P | I | K | W | T | A | P | E | A | A | L | F | G | R |
| Query Conservation |   |
  |   |   |
|
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | R | G | I | I | Y | R | D | L | K | L | D | N | V | L | L | D | S | E | G | H | I | K | L | T | D | Y | G | M | C | K | E | . |
G | L | R | P | G | D | T | T | S | T | F | C | G | T | P | N | Y | I | A | P | E | I | L | R | G | E | D |
| Template Known Secondary structure |   |
 | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
| B |
| . |
|
|
| T | T |
|
| B |
|
|
|
| S |
| G | G | G |
|
|  |  |  |  | T | T |
|
|
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | |
. | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | |
|
. | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | T | V | K | S | D | V | W | S | F | G | I | L | L | T | E | L | I | T | K | G | R | V | P | Y | P | G | M | N | . |
. |
N | R | E | V | L | E | Q | V | E | H | G | Y | H | M | P | C | P | P | G | C | P | A | S | L | Y | E | V | M | E |
| Query Conservation |   |
  |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   | . | . |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
| Template Sequence |   |
Y | G | F | S | V | D | W | W | A | L | G | V | L | M | F | E | M | M | A | . |
G | R | S | P | F | D | I | V | G | S | N | T | E | D | Y | L | F | Q | V | I | L | E | K | Q | I | R | I | P | R | S | L | S | V | K | A | A | S | V | L | K |
| Template Known Secondary structure |   |
B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
|   |
|   |   |
481 | . | . | . | . | . | . | . | . | 490 | . | |
|
|
|
|
|
. | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
Q | A | W | R | L | D | P | E | E | R | P | . |
. |
. |
. |
. |
. |
T | F | E | Y | L | Q | S |
| Query Conservation |   |
  |
|   |   |   |
|
|   |   |
|
| . | . | . | . | . | . |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Template Sequence |   |
S | F | L | N | K | D | P | K | E | R | L | G | C | H | P | Q | T | G | F | A | D | I | Q | G |
| Template Known Secondary structure |   |
 |  | T |
| S |
| T | T | T | S | T | T |
| S | T | T | T |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
485 | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . |
|   |