Job Description P14234 Confidence 100.00% Date Wed Jul 10 14:36:25 BST 2013 Rank 194 Aligned Residues 251 % Identity 26% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		248	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	N	S	I	A	L	E	R	R	L	G	T	G	C	F	G	D	V	W	L	G	T	W	N	C	S	T	K	V	A	V	K	T	L	K	P	G	T	M	S	P	K	A	F	L	E	E	A	Q	I	M	K	L	L	R	H	D	K	L	V
Query Conservation
Alig confidence																									.
Template Conservation																									.
Template Sequence		A	R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L
Template Known Secondary structure		T	T	T											T	T									.	T	T										G	G	G														S					T	T	B
Template Predicted Secondary structure																									.
Template SS confidence
		205	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
		308	.	310	.	.	.	.	.	.						.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure											.	.	.	.	.
Query SS confidence											.	.	.	.	.
Query Sequence		Q	L	Y	A	V	V	S	E	E	.	.	.	.	.	P	I	Y	I	V	T	E	F	M	C	Y	G	S	L	L	D	F	L	K	D	R	E	G	Q	N	L	M	L	P	H	L	V	D	M	A	A	Q	V	A	E	G	M	A	Y	M	E
Query Conservation											.	.	.	.	.
Alig confidence											.	.	.	.	.																							.	.	.
Template Conservation																																						.	.	.
Template Sequence		G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	T	T	.	.	.	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H
Template Known Secondary structure												T	T												T	T		B										.	.	.	B
Template Predicted Secondary structure																																						.	.	.
Template SS confidence
		264	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.				300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		363	.	.	.									.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.				.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
Predicted Secondary structure						.	.	.	.	.	.	.	.																															.	.	.
Query SS confidence						.	.	.	.	.	.	.	.																															.	.	.
Query Sequence		R	M	N	Y	.	.	.	.	.	.	.	.	I	H	R	D	L	R	A	A	N	I	L	V	G	E	Y	L	I	C	K	I	A	D	F	G	L	A	R	L	I	E	.	.	.	D	N	E	Y	N	P	Q	Q	G	T	K	F	P	I	K
Query Conservation						.	.	.	.	.	.	.	.																															.	.	.
Alig confidence						.	.	.	.	.	.	.	.																															.	.	.
Template Conservation
Template Sequence		I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R
Template Known Secondary structure		S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T						T	T	T	T													G	G
Template Predicted Secondary structure
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
		412	.	.	.	.	.	.	.	420	.	.							.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.
Predicted Secondary structure													.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence													.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		W	T	A	P	E	A	A	L	F	G	R	.	.	.	.	.	.	F	T	V	K	S	D	V	W	S	F	G	I	L	L	T	E	L	I	T	K	G	R	V	P	Y	P	G	M	N	N	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation													.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																						.
Template Sequence		Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D	P
Template Known Secondary structure		G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure																																						.
Template SS confidence
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
				453	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470							.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Predicted Secondary structure		.	.																			.	.	.	.	.	.
Query SS confidence		.	.																			.	.	.	.	.	.
Query Sequence		.	.	R	E	V	L	E	Q	V	E	H	G	Y	H	M	P	C	P	P	G	.	.	.	.	.	.	C	P	A	S	L	Y	E	V	M	E	Q	A	W	R	L	D	P	E	E	R	P	T	F	E	Y	L	Q	S	F	L	E	D	Y
Query Conservation		.	.																			.	.	.	.	.	.
Alig confidence		.	.																			.	.	.	.	.	.
Template Conservation
Template Sequence		S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure											T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D