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Job DescriptionP14234
Confidence100.00%DateWed Jul 10 14:36:25 BST 2013
Rank70Aligned Residues261
% Identity33%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   242.......250.........260.........270.. .......280....... ..290.....
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Query Sequence  DAWEIDRNSIALERRLGTGCFGDVWLGTWNC. . . . . STKVAVKTLKPGTMS. PKAFLEEA
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREI
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   840.........850.........860.........870.........880.........890.........
 
   296...300.........310.........320.........330.........340.........350.....
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Query Sequence  QIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVA
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Template Sequence  EILKSLQHDNIVKYKGVCYSN. LKLIMEYLPYGSLRDYLQKHKE. RIDHIKLLQYTSQIC
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TT
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   900.........910.........920 .........930.........940.. .......950.......
 
   356...360.........370.........380.........390.........400.........410.....
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Query Sequence  EGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAP
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Template Sequence  KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEKVKEPGESPIFWYAP
Template Known Secondary structure  TTT




GGGTT


TT


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   962.......970.........980.........990.........1000.........1010.........1020.
 
   416...420.........430.........440......... 450.........
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Query Sequence  EAALFGRFTVKSDVWSFGILLTELITKGRVPYPG. . . . . . . . . . . . . . . . MNNREVLEQV
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Template Sequence  ESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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   1024.....1030.........1040......... 1050.........1060.........1070.........1080..
 
   460.........470.........480.........490.........500.....
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Query Sequence  EHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFT
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRD
Template Known Secondary structure  TT





TT

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   1083......1090.........1100.........1110.........1120........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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