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Job DescriptionP14234
Confidence100.00%DateWed Jul 10 14:36:25 BST 2013
Rank226Aligned Residues266
% Identity33%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   243......250.........260.. .......270.........280. ........290......
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Query Sequence  AWEIDRNSIALERRLGTGCF. . . . GDVWLGTWNCSTKVAVKTL. . KPGTMSPKAFLEEAQ
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Template Sequence  CFAGKTSSISDLKEVPRKNITLIRGLVYEGQV. SPLQVAVKTLPEVCSEQDELDFLMEAL
Template Known Secondary structure  TT
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   1097..1100.........1110.........1120........ .1130.........1140.........1150.....
 
   297..300.........310..... ....320.........330..... ....340.........350
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Query Sequence  IMKLLRHDKLVQLYAVVSE. EPIYIVTEFMCYGSLLDFLK. . . . . DREGQNLMLPHLVDM
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Template Sequence  IISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHV
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   1170.........1180.........1190.........1200.........1210.........1220.........
 
   351........360.........370.........380.........390.........400.........410
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Query Sequence  AAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPI
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Template Sequence  ARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYAMLPV. . . . . .
Template Known Secondary structure  TT


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   1230.........1240.........1250.........1260.........1270.........1280...
 
   411........420.........430.........440.........450.........460.........470
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Query Sequence  KWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPG
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Template Sequence  KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKN
Template Known Secondary structure  GG

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   1294.....1300.........1310.........1320.........1330.........1340.........1350...
 
   471........480.........490.........500........ .510.....
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Query Sequence  CPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTE. . PQYQPGD
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Template Sequence  CPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIE
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   1354.....1360.........1370.........1380.........1390.........1400
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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