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Job DescriptionP14234
Confidence100.00%DateWed Jul 10 14:36:25 BST 2013
Rank7Aligned Residues370
% Identity35%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å
Model Dimensions (Å)X:86.938 Y:66.406 Z:54.245

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   125....130.........140.........150.........160.........170.........180....
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Query Sequence  DSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIK
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Template Sequence  DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVH. . . . . DVRFH
Template Known Secondary structure 
TTSS
TTB
BS

TTT

TT
TTBTT
.....TT
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   3......10.........20.........30.........40.........50.. .....
 
   185....190.........200.........210.........220.........230.........240...
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Query Sequence  HYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDA.
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Template Sequence  HFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDC
Template Known Secondary structure 
TTS
TTS

BSSTS

TTSSS


SB



TT


B

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   58.60.........70.........80.........90.........100.........110.......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKL
Template Known Secondary structure 


TTS
TTTSTTB
TT

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   118.120.........130.........140.........150.........160.........170.......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  YSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVE
Template Known Secondary structure  SSS


TT

SSTTTT
TT


TTS
SS
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   178.180.........190.........200.........210.........220.........230.......
 
   244.....250.........260...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . WEIDRNSIALERRLGTGCFG
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Template Conservation   
      
   
                                        

 
 

Template Sequence  YLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFG
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
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   238.240.........250.........260.........270.........280.........290.......
 
   264.....270.... .....280...... ...290.........300.........310........
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Query Sequence  DVWLGTWNCST. . . KVAVKTLKPGTM. . SPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPI
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Template Sequence  SVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEAL
Template Known Secondary structure 
SS





SSTTTT


TTB

SSS
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   351........360.........370.........380.........390.........400.........410
 
   319320.........330.........340.........350.........360.........370........
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Query Sequence  YIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILV
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Template Sequence  MLVMEMAGGGPLHKFLVGKRE. EIPVSNVAELLHQVSMGMKYLEEKNFVHRNLAARNVLL
Template Known Secondary structure 

TT
BTT
TT.TS
TT


S

SGGG
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   411........420.........430. ........440.........450.........460.........
 
   379380.........390.........400.........410.........420.........430........
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Query Sequence  GEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTE
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Template Sequence  VNRHYAKISDFGLSKAL. . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWE
Template Known Secondary structure  TT


STTTT
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TTS




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   470.........480...... ...490.........500.........510.......
 
   439440.........450.........460.........470.........480.........490........
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Query Sequence  LITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQS
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Template Conservation    
 
  
            
        
   
     

  
    
  

    
  
Template Sequence  ALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQ
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
SSTTTS

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   532.......540.........550.........560.........570.........580.........590.
 
   499500.........510..
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Query Sequence  FLEDYFTSTEPQYQ
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Template Conservation   
            
Template Sequence  RMRACYYSLASKVE
Template Known Secondary structure  S
S

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   592.......600.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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