|   |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 290 | . | . | . |
| Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | I | D | R | N | S | I | A | L | E | R | R | L | G | T | G | C | F | G | D | V | W | L | G | T | W | N | C | S | T | K | V | A | V | K | T | L | K | P | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | M | S | P | K | A | F | L | E |
| Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |
|   |
|
|   |   |   |   |   |   | . | . |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
D | K | S | G | R | Q | W | K | L | K | S | F | Q | T | R | D | N | Q | G | I | L | Y | E | A | A | P | T | S | . |
. |
K | F | S | L | K | L | D | A | K | D | G | R | L | F | N | E | Q | N | F | F | Q | R | A | A | K | P | L | Q | V | N |
| Template Known Secondary structure |   |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |  | T | T | S | T |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
|   |
|   |   |
294 | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
|
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | A | Q | I | M | K | L | L | R | H | D | K | L | V | Q | L | Y | A | V | V | S | E | . |
. |
E | P | I | Y | I | V | T | E | F | M | C | Y | G | S | L | L | D | F | L | K | D | R | E | G | Q | N | L | M | L | P | H | L | V | D | M | A |
| Query Conservation |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |   | . | . |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
K | W | K | K | L | Y | S | T | P | L | L | A | I | P | T | C | M | G | F | G | V | H | Q | D | K | Y | R | F | L | V | L | P | S | L | . |
G | R | S | L | Q | S | A | L | D | V | S | P | K | H | V | L | S | E | R | S | V | L | Q | V | A |
| Template Known Secondary structure |   |
 |  |  |  |  | T | T |
| T | T |
| S |
|
|
|
|
|  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  | S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
|   |
|   |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | |
|
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | |
|
|
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
| . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
| Query Sequence |   |
A | Q | V | A | E | G | M | A | Y | M | E | R | M | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | G | E | Y | L | I | C | K | . |
. |
I | A | D | F | G | L | A | R | L | I | E | D | N | E | Y | N | P | Q | Q | G | T | . |
. |
. |
| Query Conservation |   |
  |   |
|
|   |
|
|   |   |
|
|   |   |   |
|
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
| . | . |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
| Template Conservation |   |
  |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
C | R | L | L | D | A | L | E | F | L | H | E | N | E | Y | V | H | G | N | V | T | A | E | N | I | F | V | D | P | E | D | Q | S | Q | V | T | L | A | G | Y | G | F | A | F | R | Y | C | P | S | G | K | H | V | A | Y | V | E | G | S | R |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
| S |
|
|
| G | G | G |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| G | G | G |
| B |
| S | S | G | G | G |
|
|
|
|
|
| T | T | S | S |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
|
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | |
|
|
|
|
. | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
K | F | P | I | K | W | T | A | P | E | A | A | L | F | G | R | F | T | V | K | S | D | V | W | S | F | G | I | L | L | T | E | L | I | T | K | G | R | V | P | Y | P | G | M | . |
. |
. |
. |
. |
N | N | R | E | V | L | E | Q |
| Query Conservation |   |
. | . | . |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |   |
|
|   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
S | P | H | E | G | D | L | E | F | I | S | M | D | L | H | K | G | C | G | P | S | R | R | S | D | L | Q | S | L | G | Y | C | M | L | K | W | L | Y | . |
G | F | L | P | W | T | N | C | L | P | N | T | E | D | I | M | K | Q | K | Q | K |
| Template Known Secondary structure |   |
| T | T |
| S |
| T | T | T |
|
|  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S |
|
| T | T | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
348 | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | |
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . |
|   |
|   |   |
459 | 460 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | |
. | . | 510 | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| Query Sequence |   |
V | E | H | G | Y | H | M | P | C | P | P | . |
. |
. |
. |
. |
G | C | P | A | S | L | Y | E | V | M | E | Q | A | W | R | L | D | P | E | E | R | P | T | F | E | Y | L | Q | S | F | L | E | D | Y | F | T | S | T | . |
E | P | Q | Y | Q |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
F | V | D | K | P | G | P | F | V | G | P | C | G | H | W | I | R | P | S | E | T | L | Q | K | Y | L | K | V | V | M | A | L | T | Y | E | E | K | P | P | Y | A | M | L | R | N | N | L | E | A | L | L | Q | D | L | R | V | S | P | Y | D |
| Template Known Secondary structure |   |
 |  |  | S |
|
|
|  |  |
| T | T | S |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
|   |
|   |   |
513 | . | . |
| Predicted Secondary structure |   |
|
|
|
| Query SS confidence |   |
|
|
|
| Query Sequence |   |
P | G | D |
| Query Conservation |   |
|   |   |
| Alig confidence |   |
|
|
|
| Template Conservation |   |
|
|   |
| Template Sequence |   |
P | I | G |
| Template Known Secondary structure |   |
|
|
|
| Template Predicted Secondary structure |   |
|
|
|
| Template SS confidence |   |
|
|
|
|   |   |
467 | . | . |
|   |