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Job DescriptionP14234
Confidence100.00%DateWed Jul 10 14:36:25 BST 2013
Rank19Aligned Residues266
% Identity37%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å
Model Dimensions (Å)X:52.751 Y:54.045 Z:41.861

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   241........250.........260.........270. ........280......... 290..
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Query Sequence  KDAWEIDRNSIALERRLGTGCFGDVWLGTWN. . . . . . CSTKVAVKTLKPGTMSPK. . AFL
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Template Sequence  DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLL
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GGG
SSSTGGG
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   714.....720.........730.........740.........750.........760.........770...
 
   293......300.........310..... ....320.........330......... 340.....
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Query Sequence  EEAQIMKLLRHDKLVQLYAVVSE. EPIYIVTEFMCYGSLLDFLKDREG. . . . . . QNLMLP
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Template Sequence  SEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMG
Template Known Secondary structure  TT


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   774.....780.........790.........800.........810.........820.........830...
 
   346...350.........360.........370.........380.........390.... .....400....
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Query Sequence  HLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARL. IEDNEYNPQQ
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Template Sequence  DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS
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SGGGTTT


TT

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   850.........860.........870.........880.........890.........900.........
 
   405....410.........420.........430.........440.........450.........460....
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Query Sequence  GTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYH
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Template Sequence  QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR
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   910.........920.........930.........940.........950.........960.........
 
   465....470.........480.........490.........500......
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Query Sequence  MPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTS
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Template Sequence  MERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
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TT

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   970.........980.........990.........1000.........1010.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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