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Job DescriptionP14234
Confidence100.00%DateWed Jul 10 14:36:25 BST 2013
Rank1Aligned Residues449
% Identity74%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:82.389 Y:88.392 Z:49.258

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   67..70.........80.........90.........100.........110.........120......
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Query Sequence  VTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDS
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Template Sequence  VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS
Template Known Secondary structure  TTSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTS
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   83......90.........100.........110.........120.........130.........140..
 
   127..130.........140.........150.........160.........170.........180......
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Query Sequence  IQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHY
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Template Conservation 
    

 
 
 
  

  
       
 



 
    
   


          
 
 
Template Sequence  IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY
Template Known Secondary structure  GGGSTTS

T
TT

TT

SSSTT
TTT
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   143......150.........160.........170.........180.........190.........200..
 
   187..190.........200.........210.........220.........230.........240......
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Query Sequence  KIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEI
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Template Conservation   
     
         
 

  

  
      
   
                   

Template Sequence  KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEI
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS



TTB
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   203......210.........220.........230.........240.........250.........260..
 
   247..250.........260.........270.........280.........290.........300......
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Query Sequence  DRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKL
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Template Sequence  PRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKL
Template Known Secondary structure 
GGGTTTTT
TTSS



TTB
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   263......270.........280.........290.........300.........310.........320..
 
   307..310.........320.........330.........340.........350.........360......
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Query Sequence  VQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNY
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Template Sequence  VQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNY
Template Known Secondary structure 


SSS


TTS

TT
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   323......330.........340.........350.........360.........370.........380..
 
   367..370.........380.........390.........400.........410.........420......
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Query Sequence  IHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVK
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Template Sequence  VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK
Template Known Secondary structure 
S

SGGG
GGG



TT


SS




TTTT
SGGGS




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   383......390.........400.........410.........420.........430.........440..
 
   427..430.........440.........450.........460.........470.........480......
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Query Sequence  SDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLD
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Template Sequence  SDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKE
Template Known Secondary structure  TTS

SSTT

TT





TT

T
SS
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   443......450.........460.........470.........480.........490.........500..
 
   487..490.........500.........510.....
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Query Sequence  PEERPTFEYLQSFLEDYFTSTEPQYQPGD
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Template Conservation 
  


   
   

         
    
Template Sequence  PEERPTFEYLQAFLEDYFTSTEPQYQPGE
Template Known Secondary structure  GGGS

TT
TT



S
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   503......510.........520.........530.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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