Job Description Q4JIM5 Confidence 100.00% Date Tue Jul 30 13:05:37 BST 2013 Rank 2 Aligned Residues 451 % Identity 90% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:70.944 Y:77.325 Z:51.145

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		108	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	Q	N	G	E	W	S	E	V	R	S	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S
Template Known Secondary structure			T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							S	S							G	G	G				S	S	S
Template Predicted Secondary structure
Template SS confidence
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
		168	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	E	K	H	S	W	Y	H	G	P	V	S	R	S	A	A	E	Y	L	L	S	S	L	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	L	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	T	T	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D
Template Known Secondary structure		G	G	G	S	T	T														G	G	G			T	T								S	S	S	T	T									T	T											T	T
Template Predicted Secondary structure
Template SS confidence
		141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
		228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	K	V	Y	V	T	A	E	S	R	F	S	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	V	T	T	L	H	Y	P	A	P	K	C	N	K	P	T	V	Y	G	V	S	P	I	H	D	K	W	E	M	E	R	T	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D
Template Known Secondary structure		S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S										S					S	S	S		S	S	S	S			B			G	G	G
Template Predicted Secondary structure
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	V	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	F	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L
Template Known Secondary structure								S	G	G	G	T	T	S	S							G	G	G	T										S	S	S	S																		T	T	B
Template Predicted Secondary structure
Template SS confidence
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	G	V	C	T	L	E	P	P	F	Y	I	V	T	E	Y	M	P	Y	G	N	L	L	D	Y	L	R	E	C	S	R	E	E	V	T	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H
Template Known Secondary structure							S	S	S	S									T	T		B								S		T	T	T	S																						T	T
Template Predicted Secondary structure
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
		408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	D	L	A	A	R	N	C	L	V	G	E	N	H	V	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	T	F	S	I	K	S	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D
Template Known Secondary structure		S			S	G	G	G					G	G	G							T	T						T	T							T	T					G	G	G
Template Predicted Secondary structure
Template SS confidence
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	D	L	L	E	K	G	Y	R	M	E	Q	P	E	G	C	P	P	K	V	Y	E	L	M	R	A	C	W	K	W	S	P	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S
Template Known Secondary structure														T	T	S			S	S	T	T			T	T	T							T	T							T	T													T		S	S	G	G
Template Predicted Secondary structure
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500
		528	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	R	P	S	F	A	E	T	H	Q	A	F	E	T	M	F	H	D	S	S	I	S	E	E	V	A	E	E	L	G	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S	I	S	D	E	V	E	K	E	L	G	K
Template Known Secondary structure		G	S												T	S		S	S	S
Template Predicted Secondary structure
Template SS confidence
		501	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.