Job Description P26450 Confidence 99.86% Date Tue Jul 30 13:13:01 BST 2013 Rank 44 Aligned Residues 152 % Identity 47% Template c1x27F_ PDB info PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas Resolution 2.70 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	A	L	Y	D	Y	K	K	E	R	E	E	D	I	D	L	H	L	G	D	I	L	T	V	N	K	G	S	L	V	A	L	G	F	S	D	G	Q	E	A	R	P	E	D	I	G	W	L	N	G	Y	N	E	T	T	G	E	R	G
Query Conservation
Alig confidence																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	I	A	L	H	S	Y	E	P	S	H	D	G	D	L	G	F	E	K	G	E	Q	L	R	I	L	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	S	G	E	W	W	K	A	Q	S	L	T	T	G	Q	E	G
Template Known Secondary structure					S	S		B				S	T	T	B			B		T	T								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.		B	T	T							S	S	S
Template Predicted Secondary structure																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		66	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.																	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
		68	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	F	P	G	T	Y	V	E	Y	I	G	R	K	R	I	S	P	P	T	P	K	P	R	P	P	R	P	L	P	V	A	P	G	S	S	K	T	E	A	D	T	E	Q	Q	A	L	P	L	P	D	L	A	E	Q	F	A	P	P	D	V
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	I	P	F	N	F	V	A	K	A	N	S	L	E	P	E	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure					G	G	G					S		S	T	T	S	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	P	P	L	L	I	K	L	L	E	A	I	E	K	K	G	L	E	C	S	T	L	Y	R	T	Q	S	S	S	N	P	A	E	L	R	Q	L	L	D	C	D	A	A	S	V	D	L	E	M	I	D	V	H	V	L	A	D	A	F	K
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	L	A	D	L	P	N	P	V	I	P	V	A	V	Y	N	E	M	M	S	L	A	Q	E	L	Q	S	P	E	D	C	I	Q	L	L	K	K	L	I	R	L	P	N	I	P	H	Q	C	W	L	T	L	Q	Y	L	L	K	H	F
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		248	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	K	L	S	Q	A	S	S	K	N	L	L	N	A	R	V	L	S	E	I	F	S	P	V	L	F	R	F	P	A	A	S	S	D	N	T	E	H	L	I	K	A	I	E	I	L	I	S	T	E	W	N	E	R	Q	P	A	P	A	L
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.			.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure																																											.	.
Query SS confidence																																											.	.
Query Sequence		P	P	K	P	P	K	P	T	T	V	A	N	N	S	M	N	N	N	M	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	.	.	D	T	A	D	G	T	F	L	V	R	D	A	S	T	K	M	H
Query Conservation																																											.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.																.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	F	F	K	N	L	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	T	H	G	S	F	L	I	R	E	S	E	S	T	.	A
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	B		S	S											T	S	S	S			T	T								S	S	S	.	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template SS confidence
																											127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.		160
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.							.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																							.	.	.	.	.	.
Query SS confidence																							.	.	.	.	.	.
Query Sequence		G	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	F	H	R	.	.	.	.	.	.	D	G	K	Y	G	F	S	D	P	L	T	F	N	S	V	V	E	L	I	N	H	Y	R	N	E	S	L	A	Q	Y	N	P	K
Query Conservation																							.	.	.	.	.	.
Alig confidence																							.	.	.	.	.	.																													.	.	.	.	.
Template Conservation																																																									.	.	.	.	.
Template Sequence		G	S	F	S	L	S	V	R	D	F	D	Q	N	Q	G	E	V	V	K	H	Y	K	I	R	N	L	D	N	G	G	F	Y	I	S	P	R	I	T	F	P	G	L	H	E	L	V	R	H	Y	T	N	A	S	D	G	.	.	.	.	.
Template Known Secondary structure		T											S	S	S													T	T	S				S	S	T	T			B	S	S													S	S	.	.	.	.	.
Template Predicted Secondary structure																																																									.	.	.	.	.
Template SS confidence
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
		420	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	D	V	K	L	L	Y	P	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	C	T	R	L	S	R	P	C	Q
Template Known Secondary structure		S	S	S
Template Predicted Secondary structure
Template SS confidence
		216	.	.	.	220	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D