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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank134Aligned Residues242
% Identity48%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   232.......240.........250.........260.........270.........280.........290.
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Query Sequence  YDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMK
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWR. GQYDVAIKMIKE. . . . . . . FIEEAKVMM
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GGGB

GGGSTTSS
T.TT


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TT
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   392.......400.........410.........420.. .......430.... .....440...
 
   292.......300.........310.........320.........330.........340.........350.
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Query Sequence  EIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAM
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Template Sequence  NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLRE. MRHRFQTQQLLEMCKDVCEAM
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.GGG


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   451........460.........470.........480........ .490.........500.........
 
   352.......360.........370.........380.........390.........400.........410.
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Query Sequence  EYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL
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Template Sequence  EYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . . . . . . . . . . . VRWSPPEVL
Template Known Secondary structure  TT


S

SGGG
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   510.........520.........530.........540... ......550..
 
   412.......420.........430.........440.........450.........460.........470.
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Query Sequence  AYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYEL
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Template Sequence  MYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTI
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TTS

TTTTS
TT





TTS
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   570.........580.........590.........600.........610.........620.........
 
   472.......480.........490.........
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Query Sequence  MRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  MYSCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
SSGGGS

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   630.........640.........650.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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