|   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
. | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
T | D | I | T | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | G | V | W | K | K | Y | S | L | T | V | A | V | K | T | L | K | E | D | T | M | E | V | E | E | F | L | K | E | A | A | V | M | K | E | . |
I | K | H | P | N | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|
|
Template Sequence |   |
D | G | Y | E | V | K | E | D | I | G | V | G | S | Y | S | V | C | K | R | C | I | H | K | A | T | N | M | E | F | A | V | K | I | I | D | K | S | . |
. |
. |
K | R | D | P | T | E | E | I | E | I | L | L | R | Y | G | Q | H | P | N | I |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  | T | T | . | . | . | T |
|
| T |  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | B |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | |
|
|
. | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
  |
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | Q | L | L | G | V | C | T | R | E | P | P | F | Y | I | I | T | E | F | M | T | Y | G | N | L | L | D | Y | L | R | E | C | N | R | Q | E | V | S | A | V | V | L | L | Y | M | A | T | Q | I | S | S | A | M | E | Y | L | E | K | K | N |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | T | L | K | D | V | Y | D | D | G | K | Y | V | Y | V | V | T | E | L | M | K | G | G | E | L | L | D | K | I | L | R | . |
. |
Q | K | F | F | S | E | R | E | A | S | A | V | L | F | T | I | T | K | T | V | E | Y | L | H | A | Q | G |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  | T | . | . |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|  |  |
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
477 | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | |
|
. | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . |
  |
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | |
|
|
|
. | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | I | H | R | D | L | A | A | R | N | C | L | V | G | E | N | H | . |
. |
. |
. |
L | V | K | V | A | D | F | G | L | S | R | L | M | T | G | D | T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | S | L | A | Y | N |
Query Conservation |   |
  |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   | . | . | . | . |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
Template Sequence |   |
V | V | H | R | D | L | K | P | S | N | I | L | Y | V | D | E | S | G | N | P | E | S | I | R | I | C | D | F | G | F | A | K | Q | L | R | A | E | N | G | L | L | M | T | . |
P | C | Y | T | A | N | F | V | A | P | E | V | L | E | R | Q |
Template Known Secondary structure |   |
 |  |
| S |
|
|
| G | G | G |  |  |  | S | S | S | S |
|
| G | G | G |  |  |  |
|
|
| T | T |
|  |  |
| B |
| T | T | S |
| B |
|
| . | S | S |
|
|
| S |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
535 | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | |
. | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
  |
  |   |
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | |
|
|
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | |
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
K | F | S | I | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | G | I | . |
. |
. |
D | L | S | Q | V | Y | E | L | L | E | K | D | Y | R | M | E | R | P | . |
. |
. |
E | G | C | P | E | K | V |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
G | Y | D | A | A | C | D | I | W | S | L | G | V | L | L | Y | T | M | L | T | . |
G | Y | T | P | F | A | N | G | P | D | D | T | P | E | E | I | L | A | R | I | G | S | G | K | F | S | L | S | G | G | Y | W | N | S | V | S | D | T | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S |  |  |  |  | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
594 | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | |
. | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . |
  |
  |   |
469 | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | E | L | M | R | A | C | W | Q | W | N | P | S | D | R | P | S | F | A | E | I | H | Q | A | F | E |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
|
|
Template Sequence |   |
K | D | L | V | S | K | M | L | H | V | D | P | H | Q | R | L | T | A | A | L | V | L | R | H | P | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
653 | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . |
  |