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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank51Aligned Residues258
% Identity37%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   237..240.........250.........260.. .......270....... ..280.........290.
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Query Sequence  MERTDITMKHKLGGGQYGEVYEGVWK. . . . KYSLTVAVKTLKEDT. MEVEEFLKEAAVMK
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Template Sequence  FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILK
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GGGTT
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   817..820.........830.........840.........850.........860.........870......
 
   292.......300....... ..310.........320.........330.........340.........
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Query Sequence  EIKHPNLVQLLGVCTR. . EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISS
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Template Sequence  ALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQR. HRARLDASRLLLYSSQICK
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   877..880.........890.........900.........910...... ...920.........930.....
 
   350.........360.........370.........380......... 390.........400.......
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Query Sequence  AMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT. . GDTYTAHAGAKFPIKWTA
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Template Sequence  GMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYA
Template Known Secondary structure  TT
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SGGGTT


TT


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   936...940.........950.........960.........970.........980.........990.....
 
   408.410.........420.........430.........440.. .......450.......
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Query Sequence  PESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG. . . . . . . . . . IDLSQVYELLEKDYR
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Template Sequence  PESLSDNIFSRQSDVWSFGVVLYELFT. YCDKSCSPSAEFLRMMVPALSRLLELLEEGQR
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T.TT
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   996...1000.........1010.........1020.. .......1030.........1040.........1050....
 
   458.460.........470.........480.........490......
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Query Sequence  MERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM
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Template Sequence  LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
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TT

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   1060.........1070.........1080.........1090........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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