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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank7Aligned Residues366
% Identity33%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å
Model Dimensions (Å)X:80.548 Y:64.345 Z:44.256

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   120.........130.........140... ......150.........160.........170.......
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Query Sequence  NSLEKHSWYHGPVSRNAAEYLLSS. . GINGSFLVRESESSPGQRSISLRYEGRVYHYRIN
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Template Sequence  DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIE
Template Known Secondary structure 
TTSS
TTB
BS

TTT

TT
TTBTT
TT
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   3......10.........20.........30.........40.........50.........60..
 
   178.180.........190.........200.........210.........220.
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Query Sequence  TASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN. . . . . . . . . . . . . . . .
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Template Sequence  RQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAM
Template Known Secondary structure 
TTS
TTS

BSSTS

TTSSS


SB



TT


B

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   63......70.........80.........90.........100.........110.........120..
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  VRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQ
Template Known Secondary structure 


TTS
TTTSTTB
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   123......130.........140.........150.........160.........170.........180..
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  TDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLK
Template Known Secondary structure 
TT

SSTTTT
TT


TTS
SS
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   183......190.........200.........210.........220.........230.........240..
 
   222.......230.........240.........250.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . KPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEG
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Template Sequence  ADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQG
Template Known Secondary structure 
TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
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   243......250.........260.........270.........280.........290.........300..
 
   260..... ....270........ .280.........290.........300.........310.....
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Query Sequence  VWKKYS. . LTVAVKTLKEDTM. . EVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIT
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Template Sequence  VYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QAEALMLVM
Template Known Secondary structure 
SS





SSTTTT


TTB

.SSS
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   356...360.........370.........380.........390.........400..... ....410....
 
   316...320.........330.........340.........350.........360.........370.....
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Query Sequence  EFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENH
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Template Sequence  EMAGGGPLHKFLVG. KREEIPVSNVAELLHQVSMGMKYLEEKNFVHRNLAARNVLLVNRH
Template Known Secondary structure 

TT
BTT.
TTTS
TT


S

SGGGTT
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   415....420........ .430.........440.........450.........460.........470...
 
   376...380.........390.........400.........410.........420.........430.....
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Query Sequence  LVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY
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Template Sequence  YAKISDFGLSKAL. . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSY
Template Known Secondary structure 


STTTT
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TTS




TT
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   474.....480...... ...490.........500.........510.........520.
 
   436...440.........450.........460.........470.........480.........490.....
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Query Sequence  GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET
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Template Conservation 
  
            
        
   
     

  
    
  

    
   
  
Template Sequence  GQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRA
Template Known Secondary structure  S

TTTT

STT





TT

TT
SSTTTS

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   536...540.........550.........560.........570.........580.........590.....
 
   496...
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Query Sequence  MFQE
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Template Conservation      
Template Sequence  CYYS
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   596...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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