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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank86Aligned Residues263
% Identity37%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260.. .......270.... .....280.......
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Query Sequence  DKWEMERTDITMKHKLGGGQYGEVYEGVWK. . . . KYSLTVAVKTLK. EDTMEVEEFLKEA
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREI
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   840.........850.........860.........870.........880.........890.........
 
   288.290.........300.........310.........320.........330.........340.......
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Query Sequence  AVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQI
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Template Sequence  EILKSLQHDNIVKYKGVCY. . SNLKLIMEYLPYGSLRDYLQK. HKERIDHIKLLQYTSQI
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   900.........910........ .920.........930......... 940.........950......
 
   348.350.........360.........370.........380.........390.........400.......
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Query Sequence  SSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTA
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Template Sequence  CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEKVKEPGESPIFWYA
Template Known Secondary structure  TTT




GGGTT


TT


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   961........970.........980.........990.........1000.........1010.........1020
 
   408.410.........420.........430.........440.. .......450.
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Query Sequence  PESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG. . . . . . . . . . . . . . . . IDLSQVYEL
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Template Sequence  PESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
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   1023......1030.........1040......... 1050.........1060.........1070.........1080.
 
   452.......460.........470.........480.........490.........
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Query Sequence  LEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  LKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQ
Template Known Secondary structure  TT





TT

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   1082.......1090.........1100.........1110.........1120.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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