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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank215Aligned Residues251
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   240.........250.........260.........270.........280.........290.........
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Query Sequence  TDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLV
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Template Sequence  RDITLLECVGKGRYGEVWRGSWQ. . GENVAVKIFSSRDEKSWFRETELYNTVMLRHENIL
Template Known Secondary structure  TTTTT..T
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   206...210.........220........ .230.........240.........250.........260...
 
   300.... .....310.........320.........330.........340.........350.....
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Query Sequence  QLLGV. . . . CTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLE
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Template Sequence  GFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLH
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TT

TT
B

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   264.....270.........280.........290......... 300.........310.........320
 
   356... 360.........370.........380......... 390.........400....
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Query Sequence  KKNF. . . . . . . . IHRDLAARNCLVGENHLVKVADFGLSRLMT. . . GDTYTAHAGAKFPIK
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Template Sequence  IEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKR
Template Known Secondary structure  S
B
STT
B

S

SGGG
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TT
TTTT








GG
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   321........330.........340.........350.........360.........370.........380
 
   405....410..... ....420.........430.........440.....
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Query Sequence  WTAPESLAYNK. . . . . . FSIKSDVWAFGVLLWEIATYGMSPYPGIDL. . . . . . . . . . . . .
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Template Sequence  YMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDP
Template Known Secondary structure  G

TT


TT
T.TB
BTTB





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   381........390.........400.........410...... ...420.........430.........
 
   446...450.........460... ......470.........480.........490......
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Query Sequence  . . SQVYELLEKDYRMERPEG. . . . . . CPEKVYELMRACWQWNPSDRPSFAEIHQAFETM
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Template Sequence  SFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
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TTS






GGGGGS

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   440.........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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