|   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | T | L | A | E | L | V | H | H | H | S | T | V | A | D | G | L | I | T | T | L | H | Y | P | A | P | K | R | N | K | P | T | I | Y | G | V | S | P | N | Y | D | K | W | E | M | E | R | T | D | I | T | M | K | H | K | L | G | G | G | Q |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |
Template Sequence |   |
E | S | L | R | D | L | I | E | Q | S | Q | S | S | G | S | G | S | G | L | P | L | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | R | T | I | A | K | Q | I | Q | M | V | K | Q | I | G | K | G | R |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
| S |
| S | S | S |
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
  |
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
Y | G | E | V | Y | E | G | V | W | K | K | Y | S | L | T | V | A | V | K | T | L | K | E | D | T | M | E | V | E | E | F | L | K | E | A | A | V | M | K | E | I | K | H | P | N | L | V | Q | L | L | G | V | C | T | R | E | . |
. |
. |
. |
Query Conservation |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|
|   |
|
|   |   |   |   |   | . | . |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | G | E | V | W | M | G | K | W | R | . |
. |
G | E | K | V | A | V | K | V | F | F | T | T | E | E | A | S | W | F | R | E | T | E | I | Y | Q | T | V | L | M | R | H | E | N | I | L | G | F | I | A | A | D | I | K | G | T | G | S | W |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  | T | . | . | T |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | S |
| G | G | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
215 | . | . | . | . | 220 | . | . | . | . | |
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 360 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
P | P | F | Y | I | I | T | E | F | M | T | Y | G | N | L | L | D | Y | L | R | E | C | N | R | Q | E | V | S | A | V | V | L | L | Y | M | A | T | Q | I | S | S | A | M | E | Y | L | E | K | K | . |
. |
. |
. |
. |
. |
. |
. |
N | F | I |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   | . | . | . | . | . | . | . | . |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
T | Q | L | Y | L | I | T | D | Y | H | E | N | G | S | L | Y | D | Y | L | K | S | T | T | . |
. |
. |
L | D | A | K | S | M | L | K | L | A | Y | S | S | V | S | G | L | C | H | L | H | T | E | I | F | S | T | Q | G | K | P | A | I | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
|
|
| T | T |
| B |  |  |  |  |  |  |  |
|
| . | . | . | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| B |
| S | T | T |
| B |
|
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
  |
  |   |
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
H | R | D | L | A | A | R | N | C | L | V | G | E | N | H | L | V | K | V | A | D | F | G | L | S | R | L | M | T | G | D | T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | S | L | A | Y | N | . |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | R | D | L | K | S | K | N | I | L | V | K | K | N | G | T | C | C | I | A | D | L | G | L | A | V | K | F | I | I | P | P | N | T | . |
. |
. |
. |
R | V | G | T | K | R | Y | M | P | P | E | V | L | D | E | S | L | N | R | N | H | F |
Template Known Secondary structure |   |
| S |
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
|
|
|
|
|
| S | . | . | . | . | S |
| S |
| G | G | G |
|
|  |  |  |  | T | S |
|
|
| T | T |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
  |
  |   |
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | S | I | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | S | Q | V | Y | E | L | L | E | K | D | Y | R | M | E |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
| . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | S | Y | I | M | A | D | M | Y | S | F | G | L | I | L | W | E | V | A | R | . |
R | C | V | S | G | G | I | V | E | E | Y | Q | L | P | Y | H | D | L | V | P | S | D | P | S | Y | E | D | M | R | E | I | V | C | I | K | K | L | R | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | B |
| B | T | T | B |
|
|
|
|
|
| T | T | T | T | T | S |
| S | S |
|
|  |  |  |  |  |  |  |  | T | T | S |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
393 | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | |
. | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . |
  |
  |   |
460 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | E | G | . |
. |
. |
. |
. |
. |
C | P | E | K | V | Y | E | L | M | R | A | C | W | Q | W | N | P | S | D | R | P | S | F | A | E | I | H | Q | A | F | E | T | M | F | Q | E | S | S | I |
Query Conservation |   |
  |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |
|
Template Sequence |   |
S | F | P | N | R | W | S | S | D | E | C | L | R | Q | M | G | K | L | M | T | E | C | W | A | H | N | P | A | S | R | L | T | A | L | R | V | K | K | T | L | A | K | M | S | E | S | Q | D | I |
Template Known Secondary structure |   |
|
|
| G | G | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
452 | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 |
  |