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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank279Aligned Residues247
% Identity20%Templatec2pvmA_
PDB info PDB header:transferaseChain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   237..240.........250.........260.........270.........280.........290......
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Query Sequence  MERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHP
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Template Sequence  GEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPV. . KKKKIKREIKILQNLGGP
Template Known Secondary structure 

GGG
SSTTT


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T
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   34.....40.........50.........60.........70... ......80.........90.
 
   297..300.........310 .........320.........330.........340.........350....
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Query Sequence  NLVQLLGVCTREPP. . FYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYL
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Template Sequence  NIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPT. . . . . LTDYDIRYYIYELLKALDYC
Template Known Secondary structure  TB


TTT







GGG.....

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   93......100.........110.........120....... ..130.........140.......
 
   355....360.........370. ........380.........390.........400.........410...
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Query Sequence  EKKNFIHRDLAARNCLV. GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAY
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Template Sequence  HSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPG. . KEYNVRVASRYFKGPELLVD
Template Known Secondary structure  TT



SGGGTTTT


TT


TT..



S

S
GGG

TT
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   148.150.........160.........170.........180..... ....190.........200.....
 
   414.....420.........430.........440.........450.
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Query Sequence  . NKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYEL. . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNAYLNKYRIEL
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S

TT
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TT


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   206...210.........220.........230.........240.........250.........260.....
 
   452.......460.........470.........480.........490..
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Query Sequence  . . . . . . . . . . . . . . . LEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQA
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Template Sequence  DPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTH
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GGGG

TTTGGG

TT

SSTTTS

S
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   266...270.........280.........290.........300.........310.........320.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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