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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank6Aligned Residues422
% Identity43%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å
Model Dimensions (Å)X:62.529 Y:73.221 Z:48.155

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   65....70.........80.........90.........100.... .....110.........120..
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Query Sequence  LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. . KNGQGWVPSNYITPVNSL
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Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVL. . EESGEWWKARSLATRKEGYIPSNYVARVDSL
Template Known Secondary structure  SS
B


SSSB

B
TT
..TTTTT

GGGTTSG
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   61........70.........80....... ..90.........100.........110........
 
   123......130.........140. ........150.........160...... ...170.....
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Query Sequence  EKHSWYHGPVSRNAAEYLL. . SSGINGSFLVRESESSPGQRSISLR. . . . . YEGRVYHYR
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Template Sequence  ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK
Template Known Secondary structure  GGSTTTT

TSTT

TT

SSSTT
TTT
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   119120.........130.........140.........150.........160.........170........
 
   176...180.........190.........200.........210.........220.........230.....
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Query Sequence  INTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKW
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Template Sequence  IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWE. . . . KDAW
Template Known Secondary structure  B

STT
SSTTSSSTTSS
SS
SS


SB










....TT
S
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   179180.........190.........200.........210.........220.........230 ....
 
   236...240.........250.........260.........270.........280.........290.....
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Query Sequence  EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH
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Template Sequence  EIPRESLKLEKKLGAGQFGEVWMATYNK. HTKVAVKTMKPGSMSVEAFLAEANVMKTLQH
Template Known Secondary structure  B

GGGTTTT.T


SS
T


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   235....240.........250.........260.. .......270.........280.........290...
 
   296...300.........310.........320.........330.........340.........350.....
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Query Sequence  PNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLE
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Template Sequence  DKLVKLHAVV. TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIE
Template Known Secondary structure  TTB

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SSS


TT
BSTTGGG

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   294.....300... ......310.........320.........330.........340.........350..
 
   356...360.........370.........380.........390.........400.........410.....
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Query Sequence  KKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNK
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Template Sequence  QRNYIHRDLRAANILVSASLVCKIADFGLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGS
Template Known Secondary structure  TT


S

SGGG
TT



TTGGG.............T

GGGS


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   353......360.........370.........380... ......390.........
 
   416...420.........430.........440.........450.........460.........470.....
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Query Sequence  FSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRAC
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Template Sequence  FTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRC
Template Known Secondary structure 

TTT

SSTT

TT





TT

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   413......420.........430.........440.........450.........460.........470..
 
   476...480.........490.........500.......
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Query Sequence  WQWNPSDRPSFAEIHQAFETMFQESSISDEVE
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Template Sequence  WKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure  T
SSGGGS

TTTS
GGG




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   473......480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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