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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank117Aligned Residues265
% Identity23%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   238.240.........250.........260.........270......... 280.........290...
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Query Sequence  ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME. . . . VEEFLKEAAVMKEI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL
Template Known Secondary structure 
GGG
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TTT

TT
T
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   78.80.........90.........100.........110.........120.........130.......
 
   294.....300.........310.........320.........330.........340.........350...
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Query Sequence  KHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEY
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Template Sequence  DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRK. . IGSFDETCTRFYTAEIVSALEY
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TTB


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   138.140.........150.........160.........170... ......180.........190.....
 
   354.....360.........370.........380.........390.........400.........410...
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Query Sequence  LEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAY
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Template Sequence  LHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . . . . . FVGTAQYVSPELLTE
Template Known Secondary structure  TT




TTT
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   196...200.........210.........220.........230 .........240.....
 
   414.....420.........430.........440.........450.........460.........470...
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Query Sequence  NKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMR
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Template Sequence  KSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVE
Template Known Secondary structure  S


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   257..260.........270....... ..280.........290........ .300.........310....
 
   474.....480.........490.........500.........510.......
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Query Sequence  ACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKRGTRG
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Template Sequence  KLLVLDATKRLGCEEMEGYGP. LKAHPFFESVTWENLHQQTPPK
Template Known Secondary structure  TTS
SSTTSSTTSGGGTT.SGGGTT

GGGGGGS



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   315....320.........330..... ....340.........350.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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