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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank4Aligned Residues433
% Identity44%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å
Model Dimensions (Å)X:68.156 Y:76.706 Z:45.696

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   66...70.........80.........90.........100.... .....110.........120...
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Query Sequence  FVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. . KNGQGWVPSNYITPVNSLE
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Template Sequence  FVALYDYESRTETDLSFKKGERLQIVNNT. EGDWWLAHSLSTGQTGYIPSNYVAPSDSIQ
Template Known Secondary structure  SS
B


SSSB

B
TT

S.SSSTTT

GGGTTSGG
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   86...90.........100.........110.... .....120.........130.........140....
 
   124.....130.........140.... .....150.........160....... ..170......
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Query Sequence  KHSWYHGPVSRNAAEYLLSSG. . INGSFLVRESESSPGQRSISLRY. . . . . EGRVYHYRI
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Template Sequence  AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKI
Template Known Secondary structure  GSTTB

S

T
TT

TT
SSSTT
TTT
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   145....150.........160.........170.........180.........190.........200....
 
   177..180.........190.........200.........210.........220.........230......
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Query Sequence  NTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKWE
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Template Sequence  RKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA. . . KDAWE
Template Known Secondary structure  B
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S
TTSS

TTSSS










SSSS...TT
SB
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   205....210.........220.........230.........240.........250...... ...260.
 
   237..240.........250.........260.........270.........280.........290......
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Query Sequence  MERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHP
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Template Sequence  IPRESLRLEVKLGQGCFGEVWMGTWNG. TTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHE
Template Known Secondary structure 

GGG
SSTT.T
TTSS



T
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   262.......270.........280........ .290.........300.........310.........320
 
   297..300.........310.........320.........330.........340.........350......
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Query Sequence  NLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEK
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Template Sequence  KLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER
Template Known Secondary structure  TB


.SSS



TTSTT

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   321........330 .........340.........350.........360.........370.........
 
   357..360.........370.........380.........390.........400.........410......
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Query Sequence  KNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKF
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Template Sequence  MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF
Template Known Secondary structure  TT


S

SGGG
GGG


TTSTTT


TT
STTS
GGGS



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   380.........390.........400.........410.........420.........430.........
 
   417..420.........430.........440.........450.........460.........470......
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Query Sequence  SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACW
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Template Sequence  TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCW
Template Known Secondary structure 
TTTT

SSTT

TT





TT

T
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   440.........450.........460.........470.........480.........490.........
 
   477..480.........490.........500....
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Query Sequence  QWNPSDRPSFAEIHQAFETMFQESSISD
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Template Sequence  RKEPEERPTFEYLQAFLEDYFTSTEPQQ
Template Known Secondary structure 
SSGGGS

TSS


S


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   500.........510.........520.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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