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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank78Aligned Residues260
% Identity37%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260.. .......270.........280........
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Query Sequence  DKWEMERTDITMKHKLGGGQYGEVYEGVWK. . . . KYSLTVAVKTLKEDTMEVEEFLKEAA
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPH. . . IADLKKEIE
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   866...870.........880.........890.........900.........910... ......920..
 
   289290.........300.........310.........320.........330.........340........
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Query Sequence  VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQIS
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Template Sequence  ILRNLYHENIVKYKGICT. ENGIKLIMEFLPSGSLKEYLPK. NKNKINLKQQLKYAVQIC
Template Known Secondary structure  T


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TT
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   928.930.........940..... ....950.........960....... ..970.........980.....
 
   349350.........360.........370.........380.........390.........400........
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Query Sequence  SAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAP
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Template Sequence  KGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKETVKDDRDSPVFWYAP
Template Known Secondary structure  TT
S

SGGGTT


TT


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   989990.........1000.........1010.........1020.........1030.........1040........
 
   409410.........420.........430.........440... ......450...
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Query Sequence  ESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGI. . . . . . . . . . . . . . . DLSQVYELLE
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Template Sequence  ECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLK
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   1051........1060.........1070...... ...1080.........1090.........1100.........
 
   454.....460.........470.........480.........490........
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Query Sequence  KDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQ
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Template Sequence  EGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
Template Known Secondary structure  TT





TT

T

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   1110.........1120.........1130.........1140.........1150....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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