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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank91Aligned Residues250
% Identity32%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260.........270..... ....280.........
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Query Sequence  DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE. . . DTMEVEEFLKEAAV
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . . VAVKMLNVTAPTPQQLQAFKNEVGV
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B

TT

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   448.450.........460.........470......... 480.........490.........500....
 
   290.........300.........310.........320.........330.........340.........
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Query Sequence  MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISS
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Template Sequence  LRKTRHVNILLFMGYST. KPQLAIVTQWCEGSSLYHHLHI. IETKFEMIKLIDIARQTAQ
Template Known Secondary structure  TT


TTB


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   505....510.........520. ........530.........540... ......550.........560..
 
   350.........360.........370.........380.........390.........400.........
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Query Sequence  AMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPE
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Template Sequence  GMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. . . . . . . . . . . SGSILWMAPE
Template Known Secondary structure  TT
B
S

SGGGTTT


TT
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TT

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   563......570.........580.........590.........600. ........610.
 
   410..... ....420.........430.........440....... ..450......... 460.
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Query Sequence  SLAYNK. . . FSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ. VYELLEKDYRME. . . . RP
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Template Sequence  VIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVR
Template Known Secondary structure  TT
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S.SS
TTTT


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   624.....630.........640.........650. ........660.........670.........680..
 
   462.......470.........480.........490.........
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Query Sequence  EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  SNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS
Template Known Secondary structure  TTS
T
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T
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   683......690.........700.........710.........720
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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