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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank8Aligned Residues373
% Identity40%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å
Model Dimensions (Å)X:89.413 Y:63.514 Z:53.302

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   123......130.........140.... .....150.........160.........170.........180
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Query Sequence  EKHSWYHGPVSRNAAEYLLSSG. . INGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS
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Template Sequence  EKMPWFHGKISREESEQIVLIGSKTNGKFLIRARD. NNGSYALCLLHEGKVLHYRIDKDK
Template Known Secondary structure  GGSTTB

S

SSS

TT
.TTTTT
T
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   164.....170.........180.........190........ .200.........210.........220..
 
   181........190.........200.........210.........220.. ....
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Query Sequence  DGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNK. . . . . . . . . . . . . . PTIY
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Template Sequence  TGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYAD
Template Known Secondary structure  TS
STT


BSSTTB
TTSSS


SB


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TT

GGGSGGGS
GGGS
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   223......230.........240.........250.........260.........270.........280..
 
   227..230.........240....... ..250.........260..... ....270...... ...280
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Query Sequence  GVSPNYDKWEMERTDITMKHK. LGGGQYGEVYEGVWKKYS. . LTVAVKTLKED. . . TMEV
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Template Sequence  PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALK
Template Known Secondary structure  TTS


SSSB

GGGTTTT
SGGG
GGG
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   355....360.........370.........380.........390.........400.........410....
 
   281........290.........300.........310.........320.........330.........340
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Query Sequence  EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVL
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Template Sequence  DELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQ. . NRHVKDKNI
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TTB

.SSS

TT
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TTS
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   415....420.........430......... 440.........450.........460.. .......470.
 
   341........350.........360.........370.........380.........390.. ......
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Query Sequence  LYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDT. . YTAHAG
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Template Sequence  IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH
Template Known Secondary structure  TT


S

SGGGTT

TTTT

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BT
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   472.......480.........490.........500.........510.........520.........530.
 
   399400.........410.........420.........430.........440.........450........
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Query Sequence  AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM
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Template Sequence  GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERM
Template Known Secondary structure  TB
GGGG





TTT

SSTT

TT


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   532.......540.........550.........560.........570.........580.........590.
 
   459460.........470.........480.........490.........
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Query Sequence  ERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  GCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD
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TT

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   592.......600.........610.........620.........630..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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