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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank2Aligned Residues451
% Identity99%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å
Model Dimensions (Å)X:65.809 Y:71.891 Z:50.132

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   62.......70.........80.........90.........100.........110.........120.
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Query Sequence  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNS
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Template Sequence  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNS
Template Known Secondary structure 
TTSS
B


STTB

B
TT

TTSS
SS
GGGSSS
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   81........90.........100.........110.........120.........130.........140
 
   122.......130.........140.........150.........160.........170.........180.
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Query Sequence  LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASD
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Template Sequence  LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASD
Template Known Secondary structure  GGGSTT

GGG

TT
SSSTT
TT

TT
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   141........150.........160.........170.........180.........190.........200
 
   182.......190.........200.........210.........220.........230.........240.
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Query Sequence  GKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKWEMERTD
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Template Conservation 
         
 

  

  
     

   
  
                   

    
Template Sequence  GKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTD
Template Known Secondary structure  S
SSTTS
BSSTT

TTSSS






S



SSS
SSSS

B

GGG
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   201........210.........220.........230.........240.........250.........260
 
   242.......250.........260.........270.........280.........290.........300.
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Query Sequence  ITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQL
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Template Sequence  ITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQL
Template Known Secondary structure  SGGGTTSSGGGT

SSSS



TTB

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   261........270.........280.........290.........300.........310.........320
 
   302.......310.........320.........330.........340.........350.........360.
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Query Sequence  LGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIH
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Template Sequence  LGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIH
Template Known Secondary structure 
SSSS


TT
BS
TTTS
TT
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   321........330.........340.........350.........360.........370.........380
 
   362.......370.........380.........390.........400.........410.........420.
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Query Sequence  RDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSD
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Template Sequence  RNLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSD
Template Known Secondary structure  S

SGGG
GGG


TT


TT



TT



GGG



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   381........390.........400.........410.........420.........430.........440
 
   422.......430.........440.........450.........460.........470.........480.
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Query Sequence  VWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPS
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Template Sequence  VWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPS
Template Known Secondary structure  TTS

SSTT

TTTTT





TT

T
SSGG
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   441........450.........460.........470.........480.........490.........500
 
   482.......490.........500.........510..
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Query Sequence  DRPSFAEIHQAFETMFQESSISDEVEKELGK
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Template Conservation   


   
   
                
  
Template Sequence  DRPSFAEIHQAFETMFQESSISDEVEKELGK
Template Known Secondary structure  GS

TS
SSS

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   501........510.........520.........530.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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