Return to main results Retrieve Phyre Job Id

Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank179Aligned Residues257
% Identity39%Templatec3zbfA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase ros; PDBTitle: structure of human ros1 kinase domain in complex with crizotinib
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260.... .....270... ......280.........290
Predicted Secondary structure 










...
..


Query SS confidence 




























. . .








. .
















Query Sequence  EMERTDITMKHKLGGGQYGEVYEGVWKKY. . . SLTVAVKTL. . KEDTMEVEEFLKEAAVM
Query Conservation              

 
 

 
        ...   



  ..            
    
Alig confidence 




























...








..
















Template Conservation        
     

 
 

 
              



 
              
   
Template Sequence  AFPREKLTLRLLLGSGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLM
Template Known Secondary structure  B

GGG


TSS
SS



SS

Template Predicted Secondary structure 















Template SS confidence 



























































   19391940.........1950.........1960.........1970.........1980.........1990........
 
   291........300.........310.........320.........330.... .....340.....
Predicted Secondary structure 


















.....

Query SS confidence 











































. . . . .










Query Sequence  KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE. . . . . VSAVVLLYMAT
Query Conservation    
 
 


              
 
    
 
   
       .....           
Alig confidence 











































.....










Template Conservation    
 
 


              
                                    
Template Sequence  SKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCV
Template Known Secondary structure  T


TTB


SSSS


TT
BS
TT

SS
Template Predicted Secondary structure 

































Template SS confidence 



























































   2002.......2010.........2020.........2030.........2040.........2050.........2060.
 
   346...350.........360.........370.........380.........390.........400.....
Predicted Secondary structure 





























Query SS confidence 



























































Query Sequence  QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKW
Query Conservation 

   
  

    





  
 
       

 


 
                    
Alig confidence 




























......
























Template Conservation                         

    ......                         
Template Sequence  DISKGCVYLERMHFIHRDLAARNCLVSVK. . . . . . DYTSPRIVKIGDFGLARDIYLPVRW
Template Known Secondary structure  TT
S


GGGS
S......SSSS





TT




GGG
Template Predicted Secondary structure 













......




















Template SS confidence 



























































   2062.......2070.........2080.........2090 .........2100.........2110.....
 
   406...410.........420.........430.........440.........450.........460.....
Predicted Secondary structure 





























Query SS confidence 



























































Query Sequence  TAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP
Query Conservation   


           



 
  
 
    
  
                          
Alig confidence 



























































Template Conservation    

           

 
 
  
 

 
   
             
             
Template Sequence  MAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCP
Template Known Secondary structure  S




TTS

SSTT

TT





TT

Template Predicted Secondary structure 


































Template SS confidence 



























































   2128.2130.........2140.........2150.........2160.........2170.........2180.......
 
   466...470.........480.........490........
Predicted Secondary structure 




Query SS confidence 
































Query Sequence  EKVYELMRACWQWNPSDRPSFAEIHQAFETMFQ
Query Conservation       
        
  

              
Alig confidence 
































Template Conservation       

   
  

  


  

   
  
  
Template Sequence  DDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRN
Template Known Secondary structure  T
SSGGGS

Template Predicted Secondary structure 






Template SS confidence 
































   2188.2190.........2200.........2210.........2220
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D