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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank245Aligned Residues249
% Identity37%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240. ........250.........260. ........270..... ....280.....
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Query Sequence  DKWEMERTD. . ITMKHKLGGGQYGEVYEGVW. . . KKYSLTVAVKTLKE. . DTMEVEEFLK
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLT
Template Known Secondary structure  TTTB

STT

SSSTTT

S
S
S
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   1067..1070.........1080.........1090.........1100.........1110.........1120......
 
   286...290.........300.........310.........320.........330.........340.....
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Query Sequence  EAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMAT
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Template Sequence  EGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGL
Template Known Secondary structure  TTSTT


TTB






SS



TT
B
TT


B
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   1127..1130.........1140.........1150.........1160.........1170.........1180......
 
   346...350.........360.........370.........380.........390.........400.....
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Query Sequence  QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKW
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Template Sequence  QVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADF. . . . . . . . . . . . . . . . . . LPVKW
Template Known Secondary structure  TT


S


GGG
TT




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GGG
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   1187..1190.........1200.........1210.........1220... .....
 
   406...410.........420.........430.........440.........450.........460.....
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Query Sequence  TAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP
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Template Sequence  MALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCP
Template Known Secondary structure  S




TTS

S
TTS
SS
TT





TT

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   1250.........1260.........1270.........1280.........1290.........1300.........
 
   466...470.........480.........490.........
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Query Sequence  EKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
Template Known Secondary structure  T
SSGGGS

T
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   1310.........1320.........1330.........1340...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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