Return to main results Retrieve Phyre Job Id

Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank3Aligned Residues441
% Identity43%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:104.281 Y:63.654 Z:48.137

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   64.....70.........80.........90.........100.... .....110.........120.
Predicted Secondary structure 





















..








Query SS confidence 








































. .
















Query Sequence  NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. . KNGQGWVPSNYITPVNS
Query Conservation                                           ..    
  
         
Alig confidence 




























.










..
















Template Conservation     

          

    

   
  .     

       
  
 

 
 
     
Template Sequence  TTFVALYDYESRTETDLSFKKGERLQIVN. NTEGDWWLAHSLSTGQTGYIPSNYVAPSDS
Template Known Secondary structure  TSS
B


SSSB

B
TT

S
.
SSSSTTT

GGGTTS
Template Predicted Secondary structure 
















.



















Template SS confidence 



























































   84.....90.........100.........110.. .......120.........130.........140..
 
   122.......130.........140.... .....150.........160....... ..170....
Predicted Secondary structure 











..










.....

Query SS confidence 






















. .






















. . . . .






Query Sequence  LEKHSWYHGPVSRNAAEYLLSSG. . INGSFLVRESESSPGQRSISLRY. . . . . EGRVYHY
Query Conservation                     
   ..  
 



               .....       
Alig confidence 






















..






















.....






Template Conservation 
    

 
 
 
  

  
       
 



 
    
   


          
 
 
Template Sequence  IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY
Template Known Secondary structure  GGGSTTS

T
TT

TT

SSSTT
TTT
Template Predicted Secondary structure 

































Template SS confidence 



























































   143......150.........160.........170.........180.........190.........200..
 
   175....180.........190.........200.........210.........220.........230....
Predicted Secondary structure 











































Query SS confidence 



























































Query Sequence  RINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDK
Query Conservation                         
                                    
Alig confidence 





















































...


Template Conservation   
     
         
 

  

  
      
   
               ...   
Template Sequence  KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA. . . KDA
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS

...

T
Template Predicted Secondary structure 




































...


Template SS confidence 



























































   203......210.........220.........230.........240.........250...... ...
 
   235....240.........250.........260.........270.........280.........290....
Predicted Secondary structure 

















Query SS confidence 



























































Query Sequence  WEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK
Query Conservation               

 
 

 
           



              
      
 
Alig confidence 




























.





























Template Conservation   

      
   

 
 

 
  
    .   



 
         
  
  

  
 
Template Sequence  WEIPRESLRLEVKLGQGCFGEVWMGTWNG. TTRVAIKTLKPGTMSPEAFLQEAQVMKKLR
Template Known Secondary structure  TB

GGGTTTT.T
TTSS


Template Predicted Secondary structure 












.









Template SS confidence 



























































   260.........270.........280........ .290.........300.........310........
 
   295....300.........310.........320.........330.........340.........350....
Predicted Secondary structure 


















Query SS confidence 



























































Query Sequence  HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYL
Query Conservation 
 


              
 
    
 
   
                  

   
  
Alig confidence 











.














































Template Conservation 




 
 
   .     

 

   


   
                  
    
  
Template Sequence  HEKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYV
Template Known Secondary structure 
TTB


.SSS


TTS

Template Predicted Secondary structure 


.















Template SS confidence 



























































   319320.........330 .........340.........350.........360.........370.......
 
   355....360.........370.........380.........390.........400.........410....
Predicted Secondary structure 

































Query SS confidence 



























































Query Sequence  EKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYN
Query Conservation 
    





  
 
       

 


 
                     


     
Alig confidence 



























































Template Conservation       

 

   
 
       

 




                     


     
Template Sequence  ERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG
Template Known Secondary structure  TT
S

SGGG
GGG



TT


SS




TTTT
SGGGS

Template Predicted Secondary structure 









































Template SS confidence 



























































   378.380.........390.........400.........410.........420.........430.......
 
   415....420.........430.........440.........450.........460.........470....
Predicted Secondary structure 

























Query SS confidence 



























































Query Sequence  KFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA
Query Conservation        



 
  
 
    
  
                               
   
Alig confidence 



























































Template Conservation    
 








 
 

 
 
  
        
   
  
 
   
      
  

  
Template Sequence  RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQ
Template Known Secondary structure 


TTS

SSTT

TT





TT

Template Predicted Secondary structure 
























Template SS confidence 



























































   438.440.........450.........460.........470.........480.........490.......
 
   475....480.........490.........500.........510
Predicted Secondary structure 











Query SS confidence 



































Query Sequence  CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL
Query Conservation       
  

                          
Alig confidence 



































Template Conservation 
   

  


   
   

         
      
Template Sequence  CWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Template Known Secondary structure  T
SSGGGS

TT
TT



S

Template Predicted Secondary structure 

















Template SS confidence 



































   498.500.........510.........520.........530...
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D