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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank65Aligned Residues242
% Identity26%Templatec3vw6B_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   234.....240.........250.........260.........270.........280.........290...
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Query Sequence  KWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEI
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Template Sequence  EYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPE. . . . . QPLHEEIALHKHL
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B
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   672.......680.........690.........700.........710... ......720......
 
   294.....300.........310.........320.........330... ......340.........350..
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Query Sequence  KHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQ. EVSAVVLLYMATQISSAME
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Template Sequence  KHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLK
Template Known Secondary structure 

TTB

TT

TT
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TT
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   733......740.........750.........760.........770.........780.........790..
 
   353......360.........370. ........380.........390.........400.........410.
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Query Sequence  YLEKKNFIHRDLAARNCLV. GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL
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Template Sequence  YLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLT. . . . . . . . . . . GTLQYMAPEII
Template Known Secondary structure  TT
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SGGG
TTT




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   793......800.........810.........820.........830 .........840.
 
   412... ....420.........430.........440.... .....450.........460.......
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Query Sequence  AYNK. . FSIKSDVWAFGVLLWEIATYGMSPYPGID. . LSQVYELLEKDYRMERPEGCPEK
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Template Sequence  DKGPRGYGKAADIWSLGCTIIEMAT. GKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAE
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GGG
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   852.......860.........870...... ...880.........890.........900.........910
 
   468.470.........480.........490..
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Query Sequence  VYELMRACWQWNPSDRPSFAEIHQA
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Template Sequence  AKAFILKCFEPDPDKRACANDLLVD
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   911........920.........930.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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