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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank96Aligned Residues258
% Identity40%Templatec3v5qB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   235....240.........250... ......260.........270........ .280.........290..
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Query Sequence  WEMERTDITMKHKLGGGQY. GEVYEGVWKKYSLTVAVKTLKEDTM. EVEEFLKEAAVMKE
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Template Sequence  QHIKRRDIVLKRELGFKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTN
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GGG


S

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S

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   531........540.........550.........560.........570.........580.........590
 
   293......300.........310.........320.........330.........340.........350..
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Query Sequence  IKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAME
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Template Sequence  LQHEHIVKFYGVC. . GDPLIMVFEYMKHGDLNKFLRA. HGPELGLSQMLHIASQIASGMV
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TTT.T




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   595....600....... ..610.........620......... 630.........640.........650.
 
   353......360.........370.........380.........390.........400.........410..
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Query Sequence  YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA
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Template Sequence  YLASQHFVHRDLATRNCLVGANLLVKIGDFGMDVYSTDYYRT. . . . . MLPIRWMPPESIM
Template Known Secondary structure  TT


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SGGG
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SGGG
B

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B
GGG

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   669670.........680.........690.........700.........710 .........720...
 
   413......420.........430.........440.........450.........460.........470..
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Query Sequence  YNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELM
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Template Sequence  YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVM
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TTTS

TTTTS
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TT

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   744.....750.........760.........770.........780.........790.........800...
 
   473......480.........490.........500
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Query Sequence  RACWQWNPSDRPSFAEIHQAFETMFQES
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Template Sequence  LGCWQREPQQRLNIKEIYKILHALGKAT
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SSGGGS

T
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   804.....810.........820.........830.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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