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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank144Aligned Residues259
% Identity34%Templatec4e1zA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260... ......270....... ..280.........
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Query Sequence  EMERTDITMKHKLGGGQYGEVYEGVWKK. . . . YSLTVAVKTLKEDT. . MEVEEFLKEAAV
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Template Sequence  VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEI
Template Known Secondary structure  B

GGG
SS
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TT

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   887..890.........900.........910.........920.........930.........940......
 
   290.........300.........310.........320.........330.........340.........
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Query Sequence  MKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISS
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Template Sequence  LRTLYHEHIVKYKGCCE. DKSVQLVMEYVPLGSLRDYLPRHC. . . VGLAQLLLFAQQICE
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   947..950.........960... ......970.........980....... ..990.........1000..
 
   350.........360.........370.........380........ .390.........400.......
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Query Sequence  AMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM. . TGDTYTAHAGAKFPIKWTA
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Template Sequence  GMAYLHAQHYIHRALAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA
Template Known Secondary structure  TT
S

SGGG
GGG



TT


TT
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   1006...1010.........1020.........1030.........1040.........1050.........1060.....
 
   408.410.........420.........430.........440.. .......450..
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Query Sequence  PESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG. . . . . . . . . . . . . . . IDLSQVYELL
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Template Sequence  PECLKECKFYYASDVWSFGVTLYELLT. YCDSNQSPHTKFTELIGHTQGQMTVLRLTELL
Template Known Secondary structure  S
T.TT
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   1066...1070.........1080.........1090.. .......1100.........1110.........1120....
 
   453......460.........470.........480.........490.........
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Query Sequence  EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  ERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPILQTAQEK
Template Known Secondary structure  T





TT

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   1125....1130.........1140.........1150.........1160.........1170.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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