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Job DescriptionP00520
Confidence100.00%DateWed Jul 10 14:19:35 BST 2013
Rank1Aligned Residues465
% Identity99%Templatec2fo0A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Resolution2.27 Å
Model Dimensions (Å)X:62.370 Y:73.319 Z:44.011

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   46...50.........60.........70.........80.........90.........100.....
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Query Sequence  ARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTK
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Template Sequence  ARW. NKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTK
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TTTT

GGGS
TTSS
B


STTB

B
TT

TTSST
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   65.. ..70.........80.........90.........100.........110.........120...
 
   106...110.........120.........130.........140.........150.........160.....
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Query Sequence  NGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISL
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Template Sequence  NGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISL
Template Known Secondary structure  TGGGTTSGGGSTT

TSSS
TT
SSSTT
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   125....130.........140.........150.........160.........170.........180....
 
   166...170.........180.........190.........200.........210.........220.....
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Query Sequence  RYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTI
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Template Conservation       
 
  
     
         
 

  

  
     

   
  
         
Template Sequence  RYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTV
Template Known Secondary structure  TT
TTS
SSTT

BSS

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   185....190.........200.........210.........220.........230.........240....
 
   226...230.........240.........250.........260.........270.........280.....
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Query Sequence  YGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK
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Template Conservation            

      
   

 
 

 
           



 

        
  
Template Sequence  YGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK
Template Known Secondary structure  SSS
SSTT

B

GGGSGGGTTSSGGGT

TTS

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   245....250.........260.........270.........280.........290.........300....
 
   286...290.........300.........310.........320.........330.........340.....
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Query Sequence  EAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMAT
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Template Sequence  EAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT
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TTB


SSSS


TT
BS
TTTS
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   305....310.........320.........330.........340.........350.........360....
 
   346...350.........360.........370.........380.........390.........400.....
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Query Sequence  QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKW
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Template Sequence  QISSAMEYLEKKNFIHRNLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKW
Template Known Secondary structure  TT
S

SGGG
GGG


TT


SS



TT



GGG
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   365....370.........380.........390.........400.........410.........420....
 
   406...410.........420.........430.........440.........450.........460.....
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Query Sequence  TAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP
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Template Sequence  TAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP
Template Known Secondary structure 



TTS

SSTT

TT





TT

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   425....430.........440.........450.........460.........470.........480....
 
   466...470.........480.........490.........500.........510.
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Query Sequence  EKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELG
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Template Sequence  EKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELG
Template Known Secondary structure  T
SSGGGS

TSSSSS

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   485....490.........500.........510.........520.........530
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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