Job Description P32020 Confidence 99.41% Date Tue Jul 30 13:21:56 BST 2013 Rank 107 Aligned Residues 190 % Identity 16% Template c2v4wB_ PDB info PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, PDBTitle: crystal structure of human mitochondrial 3-hydroxy-3-2 methylglutaryl-coenzyme a synthase 2 (hmgcs2) Resolution 1.70 Å

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		31	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.			.	.	.	.	80	.	.				.	.	.
Predicted Secondary structure																																															.	.								.	.	.
Query SS confidence																																															.	.								.	.	.
Query Sequence		N	S	R	D	Y	P	D	M	A	K	E	A	G	Q	K	A	L	E	D	A	Q	I	P	Y	S	A	V	E	Q	A	C	V	G	Y	V	Y	G	D	S	T	S	G	Q	R	A	.	.	I	Y	H	S	L	G	L	.	.	.	T	G	I
Query Conservation																																															.	.								.	.	.
Alig confidence																																															.	.								.	.	.
Template Conservation
Template Sequence		V	Q	E	D	I	N	S	L	C	L	T	V	V	Q	R	L	M	E	R	I	Q	L	P	W	D	S	V	G	R	L	E	V	G	T	E	T	I	I	D	K	S	K	A	V	K	T	V	L	M	E	L	F	Q	D	S	G	N	T	D	I
Template Known Secondary structure		T	T																			T			G	G	G									S			S		S	S	S							G	G	G	T	G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		98	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.			.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
Predicted Secondary structure																															.	.
Query SS confidence																															.	.
Query Sequence		P	I	I	N	V	N	N	N	C	S	T	G	S	T	A	L	F	M	A	H	Q	L	I	Q	G	G	L	A	N	.	.	C	V	L	A	L	G	F	E	K	M	E	R	G	S	I	G	T	K	F	S	D	R	T	T	P	T	D	K	H
Query Conservation																															.	.
Alig confidence																															.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	G	I	D	T	T	N	A	C	Y	G	G	T	A	S	L	F	N	A	A	N	W	M	E	S	S	S	W	D	G	R	Y	A	M	V	V	C	G	D	I	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		B						S	G	G	G														T	S	T	T			S												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		158	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
		144	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	V	L	I	D	K	Y	G	L	S	A	H	P	I	T	P	Q	M	F	G	Y	A	G	K	E	H	M	E	K	Y	G	T	K	V	E	H	F	A	K	I	G	W	K	N	H	K	H	S	V	N	N	T	Y	S	Q	F	Q	D	E
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	S	L	E	E	V	M	K	S	K	P	V	F	D	F	L	T	I	L	Q	C	C	P	T	S	D	G	A	A	A	A	I	L	S	S	E	E	F	V	Q	Q	Y	G	L	Q	S	K	A	V	E	I	V	A	Q	E	M	M	T	D	L
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	V	Y	P	S	G	N	A	R	P	T	G	G	A	G	A	V	A	M	L	I	G	P	K	A	.	.	.	.	.	.	.	P	L	A	L	E	R	G	L	R	G	T	H	M	E	N	V
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.				S	S	T	T	G	G	G												S	S		.	.	.	.	.	.	.	S					T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Template SS confidence
															199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.								.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		264	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280																						.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		P	S	T	F	E	E	K	S	I	I	K	V	V	G	Y	D	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	K	E	A	A	R	R	C	Y	E	K	S	G	L	T	P	N	D	V	D	V	I
Query Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Y	D	F	Y	K	P	N	L	A	S	E	Y	P	I	V	D	G	K	L	S	I	Q	C	Y	L	R	A	L	D	R	C	Y	T	S	Y	R	K	K	I	Q	N	Q	W	K	Q	A	G	S	D	R	P	F	T	L	D	D	L	Q	Y	M
Template Known Secondary structure			S						T	T		S																																			T	T							G	G	G		S
Template Predicted Secondary structure
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
		303	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	H	D	C	F	S	V	N	E	L	I	T	Y	E	A	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	F	H	T	P	F	C	K	M	V	Q	K	S	L	A	R	L
Template Known Secondary structure						S	S
Template Predicted Secondary structure
Template SS confidence
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D