Job Description P32020 Confidence 99.88% Date Tue Jul 30 13:21:56 BST 2013 Rank 65 Aligned Residues 288 % Identity 23% Template c2uv9B_ PDB info PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 Resolution 3.1 Å

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		38	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.						.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																		.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	A	K	E	A	G	Q	K	A	L	E	D	A	Q	I	P	.	.	.	.	.	Y	S	A	V	E	Q	A	C	V	G	Y	V	Y	G	D	S	T	S	G	Q	R	A	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																		.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																		.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Y	V	L	V	S	V	A	E	A	L	L	S	S	G	I	T	D	P	Y	E	F	Y	K	Y	V	H	L	S	E	V	G	N	C	I	G	S	G	V	G	G	T	S	A	L	R	G	M	Y	K	D	R	Y	L	D	K	P	V	Q	K	D
Template Known Secondary structure													T	T	T		S	S	G	G	G					S		G	G	G								S	S											T	T	T	T	T	T					S
Template Predicted Secondary structure
Template SS confidence
		1189	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.
																	77	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	H	S	L	G	L	T	G	I	P	I	I	N	V	N	N	N	C	S	T	G	S	T	A	L	F	M	A	H	Q	L	I	Q	G	G	L	A	N	C	V	L	A	L	G	F
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.									.
Template Conservation																									.
Template Sequence		I	L	Q	E	S	F	V	N	T	M	A	A	W	V	N	M	L	L	L	S	S	T	G	.	P	I	K	T	P	V	G	A	C	A	T	A	V	E	S	L	D	V	G	Y	D	T	I	M	Q	G	K	A	R	V	C	L	V	G	G	F
Template Known Secondary structure		T	T	G	G	G	S												T						.		B						G	G	G														T	T	T	S		S
Template Predicted Secondary structure																									.
Template SS confidence
		1249	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.		.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	M	E	R	G	S	I	G	T	K	F	S	D	R	T	T	P	T	D	K	H	I	E	V	L	I	D	K	Y	G	L	S	A	H	P	I	T	P	Q	M	F	G	Y	A	G	K	E	H	M	E	K	Y	G	T	K	V	E	H	F
Query Conservation
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	D	F	Q	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	G	S
Template Known Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1308	.	1310	.	.																																																					.	.	.
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	K	I	G	W	K	N	H	K	H	S	V	N	N	T	Y	S	Q	F	Q	D	E	Y	S	L	E	E	V	M	K	S	K	P	V	F	D	F	L	T	I	L	Q	C	C	P	T	S	D	G	A	A	A	A	I	L	S	S	E	E	F
Query Conservation
Alig confidence																											.	.	.	.	.						.	.	.
Template Conservation																											.	.	.	.	.						.	.	.
Template Sequence		Y	E	F	A	N	M	G	A	T	S	N	A	K	E	E	F	A	R	G	R	E	P	G	E	M	.	.	.	.	.	S	R	P	T	S	.	.	.	T	T	R	N	G	F	M	E	S	Q	G	C	G	V	Q	V	I	M	T	A	Q	L
Template Known Secondary structure								T		B								T	T	T			T	T	S	S	.	.	.	.	.			S	S	B	.	.	.	T	T				B		B	B
Template Predicted Secondary structure																											.	.	.	.	.						.	.	.
Template SS confidence
		1316	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340						.	.	.	.	.				.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	Q	Q	Y	G	L	Q	S	K	A	V	E	I	V	A	Q	E	M	M	T	D	L	P	S	T	F	E	E	K	S	I	I	K	V	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence													.										.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.										.	.	.	.	.
Template Sequence		A	L	E	M	G	V	P	I	Y	G	I	.	V	A	M	T	S	T	A	T	D	.	.	.	.	.	K	I	G	R	S	V	P	A	P	G	Q	G	V	L	T	T	A	R	E	K	S	G	N	F	P	S	P	L	L	D	I	K	Y	R
Template Known Secondary structure						T							.										.	.	.	.	.		S		S		S	S				S		G	G	G	G	G						S	S			G	G	G	S
Template Predicted Secondary structure													.										.	.	.	.	.
Template SS confidence
		1368	.	1370	.	.	.	.	.	.	.	.		.	1380	.	.	.	.	.	.	.						.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	R	Q	L	E	L	R	R	Q	Q	I	K	Q	W	K	E	S	E	Y	L	Y	L	Q	E	E	V	A	A	I	K	S	Q	R	S	E	E	D	G	P	F	D	E	T	A	Y	L	R	E	R	T	E	H	I	E	R	E	A	R	R	Q
Template Known Secondary structure																														T	T	S	S			S	S	S
Template Predicted Secondary structure
Template SS confidence
		1422	.	.	.	.	.	.	.	1430	.	.	.	.	.	.	.	.	.	1440	.	.	.	.	.	.	.	.	.	1450	.	.	.	.	.	.	.	.	.	1460	.	.	.	.	.	.	.	.	.	1470	.	.	.	.	.	.	.	.	.	1480	.
															277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310		.	.	.	.	.	.	.	.	.	320	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	G	Y	D	M	S	K	E	A	A	R	R	C	Y	E	K	S	G	L	T	P	N	D	V	D	V	I	E	L	H	D	C	F	S	V	.	N	E	L	I	T	Y	E	A	L	G	L	C
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.																																			.											.	.
Template Conservation																																																												.	.
Template Sequence		E	A	E	A	Q	T	S	F	G	N	E	F	W	R	R	D	S	R	I	A	P	L	R	G	A	L	A	T	W	G	L	T	I	D	D	L	G	V	A	S	F	H	G	T	S	T	V	A	N	D	K	N	E	S	D	V	I	C	.	.
Template Known Secondary structure											T	S	T	T	T	T		T	T	S									T	T	T			G	G	G										S														.	.
Template Predicted Secondary structure																																																												.	.
Template SS confidence
		1482	.	.	.	.	.	.	.	1490	.	.	.	.	.	.	.	.	.	1500	.	.	.	.	.	.	.	.	.	1510	.	.	.	.	.	.	.	.	.	1520	.	.	.	.	.	.	.	.	.	1530	.	.	.	.	.	.	.	.	.
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.		.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
Predicted Secondary structure																																.																									.	.	.	.	.
Query SS confidence																																.																									.	.	.	.	.
Query Sequence		P	E	G	Q	G	G	T	L	V	D	R	G	D	N	T	Y	G	G	K	W	V	I	N	P	S	G	G	L	I	S	.	K	G	H	P	L	G	A	T	G	L	A	Q	C	A	E	L	C	W	Q	L	R	G	E	A	.	.	.	.	.
Query Conservation																																.																									.	.	.	.	.
Alig confidence		.	.	.	.	.	.																	.	.	.						.																									.	.	.	.	.
Template Conservation		.	.	.	.	.	.																	.	.	.
Template Sequence		.	.	.	.	.	.	Q	Q	L	K	H	L	G	R	T	K	G	N	A	V	L	G	.	.	.	I	F	Q	K	Y	L	T	G	H	P	K	G	A	A	G	A	W	M	L	N	G	C	L	Q	V	L	N	T	G	I	V	P	G	N	R
Template Known Secondary structure		.	.	.	.	.	.							T			T	T						.	.	.			T						B		S	S															T	T							T
Template Predicted Secondary structure		.	.	.	.	.	.																	.	.	.
Template SS confidence
								1540	.	.	.	.	.	.	.	.	.	1550	.	.	.	.	.				.	.	.	.	1560	.	.	.	.	.	.	.	.	.	1570	.	.	.	.	.	.	.	.	.	1580	.	.	.	.	.	.	.	.	.	1590
																					377	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	K	R	Q	V	P	G	A	K	V	A	L	Q	H	N	L	G	L	G	G	A	V	V	V	T	L	Y
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		N	A	D	N	V	D	K	V	M	E	Q	F	D	Y	I	V	Y	P	S	R	S	I	K	T	D	G	I	K	A	F	S	V	T	S	F	G	F	G	Q	K	G	A	Q	A	I	G
Template Known Secondary structure		T			S	B		G	G	G	G	G		T	T					S	S					S												T	T	T
Template Predicted Secondary structure
Template SS confidence
		1591	.	.	.	.	.	.	.	.	1600	.	.	.	.	.	.	.	.	.	1610	.	.	.	.	.	.	.	.	.	1620	.	.	.	.	.	.	.	.	.	1630	.	.	.	.	.	.