Job Description P32020 Confidence 99.39% Date Tue Jul 30 13:21:56 BST 2013 Rank 111 Aligned Residues 265 % Identity 17% Template c2p8uB_ PDB info PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i Resolution 2.00 Å

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		31	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.			.	.	.	.	80	.	.	.	.				.
Predicted Secondary structure																																															.	.										.	.	.
Query SS confidence																																															.	.										.	.	.
Query Sequence		N	S	R	D	Y	P	D	M	A	K	E	A	G	Q	K	A	L	E	D	A	Q	I	P	Y	S	A	V	E	Q	A	C	V	G	Y	V	Y	G	D	S	T	S	G	Q	R	A	.	.	I	Y	H	S	L	G	L	T	G	.	.	.	I
Query Conservation																																															.	.										.	.	.
Alig confidence																																															.	.										.	.	.
Template Conservation
Template Sequence		D	R	E	D	I	N	S	L	C	M	T	V	V	Q	N	L	M	E	R	N	N	L	S	Y	D	C	I	G	R	L	E	V	G	T	E	T	I	I	D	K	S	K	S	V	K	T	N	L	M	Q	L	F	E	E	S	G	N	T	D	I
Template Known Secondary structure		T	T																		T	T			G	G	G									S			S		S	S	S							G	G	G	T	G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.			.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
Predicted Secondary structure																															.	.
Query SS confidence																															.	.
Query Sequence		P	I	I	N	V	N	N	N	C	S	T	G	S	T	A	L	F	M	A	H	Q	L	I	Q	G	G	L	A	N	.	.	C	V	L	A	L	G	F	E	K	M	E	R	G	S	I	G	T	K	F	S	D	R	T	T	P	T	D	K	H
Query Conservation																															.	.
Alig confidence							.																								.	.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation							.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	G	I	D	T	.	T	N	A	Y	G	G	T	A	A	V	F	N	A	V	N	W	I	E	S	S	S	W	D	G	R	Y	A	L	V	V	A	G	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		B					.																			S	T	T			S										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure							.																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		121	.	.	.	.		.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		144	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	V	L	I	D	K	Y	G	L	S	A	H	P	I	T	P	Q	M	F	G	Y	A	G	K	E	H	M	E	K	Y	G	T	K	V	E	H	F	A	K	I	G	W	K	N	H	K	H	S	V	N	N	T	Y	S	Q	F	Q	D	E
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	S	L	E	E	V	M	K	S	K	P	V	F	D	F	L	T	I	L	Q	C	C	P	T	S	D	G	A	A	A	A	I	L	S	S	E	E	F	V	Q	Q	Y	G	L	Q	S	K	A	V	E	I	V	A	Q	E	M	M	T	D	L
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	I	A	V	Y	A	T	G	N	A	R	P	T	G	G	V	G	A	V	A	L	L	I	G	P	.	.	.	.	.	.	.	.	N	A	P	L	I	F	E	R	G	L	R	G	T	H	M	Q	H
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.						S	S	T	T	G	G	G												S	.	.	.	.	.	.	.	.	S		S					T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Template SS confidence
													160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.									.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
		264	.	.	.	.	.	270	.	.	.	.	.																							.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
Predicted Secondary structure														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		P	S	T	F	E	E	K	S	I	I	K	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	G	Y	D	M	S	K	E	A	A	R	R	C	Y	E	K	S	G	L	T	P	N	D	V	D	V
Query Conservation														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	Y	D	F	Y	K	P	D	M	L	S	E	Y	P	I	V	D	G	K	L	S	I	Q	C	Y	L	S	A	L	D	R	C	Y	S	V	Y	C	K	K	I	H	A	Q	W	Q	K	E	G	N	D	K	D	F	T	L	N	D	F	G	F
Template Known Secondary structure				S						T	T		S	S																																		T	T							G	G	G		S
Template Predicted Secondary structure
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.
Predicted Secondary structure																																																						.	.	.	.	.	.	.	.
Query SS confidence																																																						.	.	.	.	.	.	.	.
Query Sequence		I	E	L	H	D	C	F	S	V	N	E	L	I	T	Y	E	A	L	G	L	C	P	E	G	Q	G	G	T	L	V	D	R	G	D	N	T	Y	G	G	K	W	V	I	N	P	S	G	G	L	I	S	K	.	.	.	.	.	.	.	.
Query Conservation																																																						.	.	.	.	.	.	.	.
Alig confidence																																																						.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		M	I	F	H	S	P	Y	C	K	L	V	Q	K	S	L	A	R	M	L	L	N	D	F	L	N	D	Q	N	R	D	K	N	S	I	Y	S	G	L	E	A	F	G	D	V	K	L	E	D	T	Y	F	D	R	D	V	E	K	A	F	M
Template Known Secondary structure							S	S																				T	T	G	G	G		G	G	G	T	T		G	G	G	T	T			G	G	G		T	T
Template Predicted Secondary structure
Template SS confidence
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
																							354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	H	P	L	G	A	T	G	L	A	Q	C	A	E	L	C	W	Q	L	R	G	E	A	G	K	R	Q	V	P	G	A	K	V	A	L	Q	H	N	L
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.																				.	.	.
Template Conservation																																				.	.	.	.																				.	.	.
Template Sequence		K	A	S	S	E	L	F	S	Q	K	T	K	A	S	L	L	V	S	N	Q	N	G	N	M	Y	T	S	S	V	Y	G	S	L	A	.	.	.	.	S	V	L	A	Q	Y	S	P	Q	Q	L	A	G	K	R	I	G	V	F	.	.	.
Template Known Secondary structure				T								T	T	G	G	G										G	G	G								.	.	.	.						S						T	T							.	.	.
Template Predicted Secondary structure																																				.	.	.	.																				.	.	.
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.					.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
		393	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	L	G	G	A	V	V	V	T	L	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	Y	G	S	G	L	A	A	T	L	Y
Template Known Secondary structure					T	T	T
Template Predicted Secondary structure
Template SS confidence
		374	.	.	.	.	.	380	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D