Job Description P39688 Confidence 100.00% Date Wed Jul 10 14:11:43 BST 2013 Rank 7 Aligned Residues 374 % Identity 37% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:81.089 Y:84.500 Z:59.226

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		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	I	Q	A	E	E	W	Y	F	G	K	L	G	R	K	D	A	E	R	Q	L	L	S	F	G	N	P	R	G	T	F	L	I	R	E	S	Q	T	T	K	G	A	Y	S	L	S	I	R	D	W	D	D	M	K	G	D	H	V	K	H
Query Conservation
Alig confidence																																							.											.	.	.	.	.
Template Conservation																																							.											.	.	.	.	.
Template Sequence		A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	N	N	G	S	Y	A	L	C	L	L	.	.	.	.	.	H	E	G	K	V	L	H
Template Known Secondary structure			G	G	G	S	T	T	B			S												S	S	S			T	T									.	T	T	T								.	.	.	.	.		T	T
Template Predicted Secondary structure																																							.											.	.	.	.	.
Template SS confidence
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.		.	200	.	.	.	.	.	.	.	.						.	210	.	.	.	.	.
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	K	I	R	K	L	D	N	G	G	Y	Y	I	T	T	R	A	Q	F	E	T	L	Q	Q	L	V	Q	H	Y	S	E	R	A	A	G	L	C	C	R	L	V	V	P	C	H	K	G	M	P	R	L	T	D	L	S	V	K	T	K	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V
Template Known Secondary structure								T	T	S				S	T	T				B	S	S									T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G
Template Predicted Secondary structure
Template SS confidence
		216	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
		263	.															.	.	.	.	.	270	.	.	.	.	.	.		.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.				.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.													.																		.	.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.													.																		.	.	.
Query Sequence		V	W	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	I	P	R	E	S	L	Q	L	I	K	R	.	L	G	N	G	Q	F	G	E	V	W	L	G	T	W	N	G	N	.	.	.	T	K	V	A	I	K	T	L	K	P	G
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.													.																		.	.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.													.																		.	.	.
Template Conservation
Template Sequence		Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E
Template Known Secondary structure		G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T											T	T												S	G
Template Predicted Secondary structure
Template SS confidence
		348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
					305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
Predicted Secondary structure		.	.	.
Query SS confidence		.	.	.
Query Sequence		.	.	.	T	M	S	P	E	S	F	L	E	E	A	Q	I	M	K	K	L	K	H	D	K	L	V	Q	L	Y	A	V	V	S	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	D	G	E	G	R	A
Query Conservation		.	.	.
Alig confidence		.	.	.																																																			.	.
Template Conservation																																																							.	.
Template Sequence		A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	.	.	Q	Q	N	R	H
Template Known Secondary structure		G	G		G	G	G																	T	T	B									S	S	S									T	T		B						.	.				T	T
Template Predicted Secondary structure																																																							.	.
Template SS confidence
		408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460			.	.	.	.	.
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																												.	.
Query SS confidence																																																												.	.
Query Sequence		L	K	L	P	N	L	V	D	M	A	A	Q	V	A	A	G	M	A	Y	I	E	R	M	N	Y	I	H	R	D	L	R	S	A	N	I	L	V	G	N	G	L	I	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	.	.
Query Conservation																																																												.	.
Alig confidence																																																												.	.
Template Conservation
Template Sequence		V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y
Template Known Secondary structure		S																						T	T				S			S	G	G	G						T	T							T	T					T	T
Template Predicted Secondary structure
Template SS confidence
		466	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
		420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	V	T	K	G	R	V	P	Y	P	G	M	N	N	R	E	V	L	E	Q	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L
Template Known Secondary structure				S		B	T	T	B		G	G	G	G																													T	T	T			S	S	T	T
Template Predicted Secondary structure
Template SS confidence
		526	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.
		480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	R	G	Y	R	M	P	C	P	Q	D	C	P	I	S	L	H	E	L	M	I	H	C	W	K	K	D	P	E	E	R	P	T	F	E	Y	L	Q	G	F	L	E	D	Y	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y
Template Known Secondary structure			T	T							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		586	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D