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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank123Aligned Residues259
% Identity39%Templatec3zosA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epithelial discoidin domain-containing receptor 1; PDBTitle: structure of the ddr1 kinase domain in complex with ponatinib
Resolution1.92 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290.. .......300.. ..
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Query Sequence  WEIPRESLQLIKRLGNGQFGEVWLGTWNG. . . . . . . . . . . . . . . . . NTKVAIKTLK. . PG
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Template Sequence  VDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDAT
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GGGTTSSGGGG
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TT

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   603......610.........620.........630.........640.........650.........660..
 
   305....310.........320.........330..... ....340.........350.......
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Query Sequence  TMSPESFLEEAQIMKKLKHDKLVQLYAVVSE. EPIYIVTEYMSKGSLLDFLKDG. . . . . .
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Template Sequence  KNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDAA
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BT




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   663......670.........680.........690.........700.........710.........720..
 
   358.360.........370.........380.........390.........400.........410..... .
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Query Sequence  EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI. E
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Template Sequence  QGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYA
Template Known Secondary structure 
S

TT


S

SGGG
GGG



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G
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   734.....740.........750.........760.........770.........780.........790...
 
   417..420.........430.........440.........450.........460.. .......470.....
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Query Sequence  DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTK. GRVPYPGMNNREV
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Template Sequence  GDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQV
Template Known Secondary structure  GG
TT
GGGS




TTT
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   794.....800.........810.........820.........830.........840.........850...
 
   476...480. ........490.........500.........510.........520..
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Query Sequence  LEQVER. . . . . . . GYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLED
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Template Sequence  IENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAE
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TT

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T
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   854.....860.........870.........880.........890.........900.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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