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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank216Aligned Residues229
% Identity24%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290.. .......300.........310.........320..
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Query Sequence  WEIPRESLQLIKRLGNGQFGEVWLGTWNG. NTKVAIKTLKPGTMSPESFLEEAQIMKKLK
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSR
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.....
 
   323......330..... ....340.........350.........360.........370.........380.
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Query Sequence  HDKLVQLYAVVSE. EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYI
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Template Sequence  HPFLTALKYSFQTHDRLCFVMEYANGGELFFHL. . SRERVFSEDRARFYGAEIVSALDYL
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   207..210.........220.........230......... 240.........250.........260....
 
   382. ......390.........400.........410.........420.........430.........440
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Query Sequence  ER. MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY
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Template Sequence  HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEPE. . . . . . . . . . . . . . . YLAPEVLED
Template Known Secondary structure  TS







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   265....270.........280.........290.........300 .........
 
   441........450.........460.........470.........480.........490.........500
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Query Sequence  GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI
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Template Sequence  NDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLS
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   324.....330.........340.... .....350.........360..... ....370.........380.
 
   501........510 .......
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Query Sequence  HCWKKDPEER. . . . . PTFEYLQ
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIM
Template Known Secondary structure  T
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   382.......390.........400...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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