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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank129Aligned Residues241
% Identity40%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280.........290.........300.........310.........320.
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Query Sequence  DVWEIPRESLQLIKRLGNGQFGEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKL
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Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMNL
Template Known Secondary structure  GGGB

GGGSTTSS
TTT

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TT
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   393......400.........410.........420.........430... ......440.....
 
   322.......330..... ....340.........350.........360.........370.........380
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Query Sequence  KHDKLVQLYAVVSE. EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY
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Template Sequence  SHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEY
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TTB


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GGG
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   453......460.........470.........480.........490.. .......500.........510.
 
   381........390.........400.........410.........420.........430.........440
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Query Sequence  IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY
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Template Sequence  LESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . . . . . . . . . . . VRWSPPEVLMY
Template Known Secondary structure  TT


S

SGGG
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   512.......520.........530.........540... ......550....
 
   441........450.........460.........470.........480.........490.........500
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Query Sequence  GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI
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Template Sequence  SKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
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TTTTS
TT





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   572.......580.........590.........600.........610.........620.........630.
 
   501........510.........520.......
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Query Sequence  HCWKKDPEERPTFEYLQGFLEDYFTAT
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   632.......640.........650........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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