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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank75Aligned Residues263
% Identity33%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280.........290.. .......300..... ....310.....
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Query Sequence  DVWEIPRESLQLIKRLGNGQFGEVWLGTWNG. . . . . NTKVAIKTLKPGT. MSPESFLEEA
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREI
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   840.........850.........860.........870.........880.........890.........
 
   316...320.........330.........340.........350.........360.........370.....
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Query Sequence  QIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVA
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Template Sequence  EILKSLQHDNIVKYKGVCY. SNLKLIMEYLPYGSLRDYLQKHKER. IDHIKLLQYTSQIC
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   900.........910........ .920.........930.........940... ......950.......
 
   376...380.........390.........400.........410.........420.........430.....
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Query Sequence  AGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAP
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Template Sequence  KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEKVKEPGESPIFWYAP
Template Known Secondary structure  TTT




GGGTT


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   962.......970.........980.........990.........1000.........1010.........1020.
 
   436...440.........450.........460......... 470.........
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Query Sequence  EAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG. . . . . . . . . . . . . . . . MNNREVLEQV
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Template Sequence  ESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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   1024.....1030.........1040......... 1050.........1060.........1070.........1080..
 
   480.........490.........500.........510.........520.......
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Query Sequence  ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTAT
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQM
Template Known Secondary structure  TT





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   1083......1090.........1100.........1110.........1120.........1130
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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