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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank70Aligned Residues253
% Identity36%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280.........290.........300........ .310........
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Query Sequence  DVWEIPRESLQLIKRLGNGQFGEVWLGTWNGNTKVAIKTLKPGTMSP. . . ESFLEEAQIM
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . VAVKMLNVTAPTPQQLQAFKNEVGVL
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B

TT

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   448.450.........460.........470......... 480.........490.........500.....
 
   319320.........330.........340.........350.........360.........370........
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Query Sequence  KKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM
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Template Sequence  RKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETK. FEMIKLIDIARQTAQGM
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   506...510.........520.........530.........540....... ..550.........560....
 
   379380.........390.........400.........410.........420.........430........
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Query Sequence  AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA
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Template Sequence  DYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. . . . . . . . . . . SGSILWMAPEVI
Template Known Secondary structure  TT
B
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SGGGTTT


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TT

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   565....570.........580.........590.........600. ........610...
 
   439440.. .......450.........460.........470.... .....480...... ...490
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Query Sequence  LYGR. . . FTIKSDVWSFGILLTELVTKGRVPYPGMNNRE. VLEQVERGYRMP. . . . CPQD
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Template Sequence  RMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSN
Template Known Secondary structure  TT
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S.SS
TTTT


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TT
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   626...630.........640.........650. ........660.........670.........680....
 
   491........500.........510.........520.........
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Query Sequence  CPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEP
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Template Sequence  CPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK
Template Known Secondary structure  S
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   685....690.........700.........710.........720...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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