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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank230Aligned Residues261
% Identity33%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   261........270.........280.. .......290.........300. ........310....
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Query Sequence  KDVWEIPRESLQLIKRLGNGQF. . . . GEVWLGTWNGNTKVAIKTL. . KPGTMSPESFLEE
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Template Sequence  NYCFAGKTSSISDLKEVPRKNITLIRGLVYEGQVS. PLQVAVKTLPEVCSEQDELDFLME
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   1095....1100.........1110.........1120......... 1130.........1140.........1150...
 
   315....320.........330..... ....340.........350........ .360........
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Query Sequence  AQIMKKLKHDKLVQLYAVVSE. EPIYIVTEYMSKGSLLDFLKDGE. . . . . GRALKLPNLV
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Template Sequence  ALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL
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   1168.1170.........1180.........1190.........1200.........1210.........1220.......
 
   369370.........380.........390.........400.........410.........420........
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Query Sequence  DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF
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Template Sequence  HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG. . . . . . MARDIYAML
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   1228.1230.........1240.........1250.........1260.........1270.. .......1280.
 
   429430.........440.........450.........460.........470.........480........
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Query Sequence  PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP
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Template Sequence  PVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPP
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   1292.......1300.........1310.........1320.........1330.........1340.........1350.
 
   489490.........500.........510.........520........
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Query Sequence  QDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATE
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Template Sequence  KNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPD
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   1352.......1360.........1370.........1380.........1390.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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