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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank133Aligned Residues237
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   267..270.........280.........290 .........300.. .......310.........320.
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Query Sequence  PRESLQLIKRLGNGQFGEVWLGTW. NGNTKVAIKTLK. . . . PGTMSPESFLEEAQIMKKL
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL
Template Known Secondary structure 
GGG
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TT
T
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   78.80.........90.........100.........110.........120.........130.......
 
   322.......330..... ....340.........350.........360.........370.........380
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Query Sequence  KHDKLVQLYAVVSE. EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY
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Template Sequence  DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYI. . RKIGSFDETCTRFYTAEIVSALEY
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   138.140.........150.........160.........170. ........180.........190.....
 
   381........390.........400.........410.........420.........430.........440
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Query Sequence  IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY
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Template Sequence  LHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . . . . . FVGTAQYVSPELLTE
Template Known Secondary structure  TT




TTT
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   196...200.........210.........220.........230 .........240.....
 
   441........450.........460.........470.........480.........490.........500
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Query Sequence  GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI
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Template Sequence  KSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVE
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   257..260.........270....... ..280.........290........ .300.........310....
 
   501........510.......
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Query Sequence  HCWKKDPEERPTFEYLQ
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Template Sequence  KLLVLDATKRLGCEEME
Template Known Secondary structure  TTS
SSTTSSTTSGGGT
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   315....320.........330.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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