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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank1Aligned Residues451
% Identity77%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:58.308 Y:104.002 Z:49.898

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   84.....90.........100.........110.........120.........130.........140...
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Query Sequence  VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS
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Template Sequence  VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS
Template Known Secondary structure  TTSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTS
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   83......90.........100.........110.........120.........130.........140..
 
   144.....150.........160.........170.........180.........190.........200...
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Query Sequence  IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESQTTKGAYSLSIRDWDDMKGDHVKHY
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Template Conservation 
    

 
 
 
  

  
       
 



 
    
   


          
 
 
Template Sequence  IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHY
Template Known Secondary structure  GGGSTTS

T
TT

TT

SSSTT
TTT
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   143......150.........160.........170.........180.........190.........200..
 
   204.....210.........220.........230.........240.........250.........260...
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Query Sequence  KIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDV
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...
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Template Sequence  KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDA. . .
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS



T...
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   203......210.........220.........230.........240.........250.........
 
   264.....270.........280.........290.........300.........310.........320...
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Query Sequence  WEIPRESLQLIKRLGNGQFGEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKH
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Template Sequence  WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRH
Template Known Secondary structure  TB

GGGTTTTT
TTSS



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   260.........270.........280.........290.........300.........310.........
 
   324.....330.........340.........350.........360.........370.........380...
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Query Sequence  DKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER
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Template Sequence  EKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER
Template Known Secondary structure  TTB


SSS


TTS

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   320.........330.........340.........350.........360.........370.........
 
   384.....390.........400.........410.........420.........430.........440...
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Query Sequence  MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF
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Template Sequence  MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF
Template Known Secondary structure  TT
S

SGGG
GGG



TT


SS




TTTT
SGGGS



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   380.........390.........400.........410.........420.........430.........
 
   444.....450.........460.........470.........480.........490.........500...
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Query Sequence  TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCW
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Template Sequence  TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCW
Template Known Secondary structure 
TTS

SSTT

TT





TT

T
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   440.........450.........460.........470.........480.........490.........
 
   504.....510.........520.........530.......
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Query Sequence  KKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
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Template Sequence  RKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Template Known Secondary structure 
SSGGGS

TT
TT



S

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   500.........510.........520.........530...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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