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Job DescriptionP39688
Confidence100.00%DateWed Jul 10 14:11:43 BST 2013
Rank85Aligned Residues250
% Identity34%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   266...270.........280.........290 .........300.........310.........320....
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Query Sequence  IPRESLQLIKRLGNGQFGEVWLGTW. NGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD
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Template Sequence  LKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELRE. . KANKEILDEAYVMASVDNP
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   707..710.........720.........730.........740..... ....750.........760....
 
   325....330.........340.........350.........360.........370.........380....
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Query Sequence  KLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERM
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Template Sequence  HVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDN. IGSQYLLNWCVQIAKGMNYLEDR
Template Known Secondary structure  TB

SSS

TT
BTSSS.

T
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   773......780.........790.........800........ .810.........820.........830.
 
   385....390.........400.........410.........420.........430.........440....
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Query Sequence  NYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFT
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Template Sequence  RLVHRDLAARNVLVKTPQHVKITDFGLA. . . . . . . KLLGAEEKVPIKWMALESILHRIYT
Template Known Secondary structure  T


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GGGTT


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   832.......840.........850......... 860.........870.........880....
 
   445....450.........460.........470.........480.........490.........500....
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Query Sequence  IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK
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Template Sequence  HQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWM
Template Known Secondary structure  TTS

TTTTS
GGGT





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   893......900.........910.........920.........930.........940.........950..
 
   505....510.........520.....
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Query Sequence  KDPEERPTFEYLQGFLEDYFT
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Template Sequence  IDADSRPKFRELIIEFSKMAR
Template Known Secondary structure  SSGGGS

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   953......960.........970...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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