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Job DescriptionQ9ERV7
Confidence99.95%DateWed Jul 10 14:21:35 BST 2013
Rank7Aligned Residues250
% Identity31%Templatec1ziwA_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 3; PDBTitle: human toll-like receptor 3 extracellular domain structure
Resolution2.10 Å
Model Dimensions (Å)X:102.497 Y:57.253 Z:50.722

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   35....40.........50.........60.........70.........80.........90....
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Query Sequence  PFLPAGNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVPWSL
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Template Sequence  PDDLPTNITVLNLTHNQ. . . LRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK. . . . L
Template Known Secondary structure 
S
S
TT
S

SS
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GGGGGGGTT
S

SS





TT....
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   46...50.........60.. .......70.........80.........90....... .
 
   95....100.........110.........120.........130.........140..... ....150...
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Query Sequence  LRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETL. PTCVPELH
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Template Conservation    
  
 

 
 
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Template Sequence  PMLKVLNLQHNELSQ. . . . . . . . . . . LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK
Template Known Secondary structure  TT



SS



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TTTTTT
TT
S

SS





S
TTTT
T
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   99100.........110... ......120.........130.........140.......
 
   154.....160....... ..170.........180
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Query Sequence  GLDALLLSHNHLSE. LPEALGALPALTF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN
Template Known Secondary structure  T



SS

S




SSS

TT



SS



B
GGGTT
S
TT
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   148.150.........160.........170.........180.........190.........200.......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                              
Template Sequence  QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT
Template Known Secondary structure 



B
TTGGGGSS

TT


TTS



TTS



TTT
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   208.210.........220.........230.........240.........250.........260.......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                              
Template Sequence  FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL
Template Known Secondary structure  TGGGGGS



TTS



TTTTTT
TT



S

BS
TTTTTT
TT

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   268.270.........280.........290.........300.........310.........320.......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                              
Template Sequence  NLKRSFTKQLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL
Template Known Secondary structure 
TT
B





TTTTTT
TT



S

B



TTTTTT
TT


TT
BS

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   328.330.........340.........350.........360.........370.........380.......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                              
Template Sequence  RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR
Template Known Secondary structure 

TTTTGGGTTS



TTS



TTTTTT
TT



SS



SGGGT
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   394.....400.........410.........420.........430.........440.........450...
 
   181..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LTV
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Template Conservation                                                              
Template Sequence  GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL
Template Known Secondary structure  T
TT



S
S

TTTTTT
TT


TTS

B
TT
SS
TTTT
TT


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   454.....460.........470.........480.........490.........500.........510...
 
   184..... 190.........200.........210....... ..220.........230...
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Query Sequence  THNRLE. RLPLTLGSLSTLQRLDLSENLLDTIPSE. . . . . . . . . IGNLRSLSELNLASNR
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Template Conservation                 
  
  
 
  
 
  
               
  
  
 

 
 
Template Sequence  SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNG
Template Known Secondary structure 
SS





TTTTTT
TT



SS

GGGGSTTSTTS


TTTT
TT



SS
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   514.....520.........530.........540.........550.........560.........570...
 
   234.....240 .........250.........260 .........270.........280.... ..
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Query Sequence  LQSLPAS. LAGLRSLRLLVLHSNLLTSV. PTGLVHLPLITRLDLRDNRLRDLP. . . . . AE
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Template Conservation 
       
  
  
  
 

 
 
          
  
  
 

 
 
           
Template Sequence  FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA
Template Known Secondary structure 




TTTTTT
TT



SS





TTTTTT
TT


TTS


B

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   574.....580.........590.........600.........610.........620.........630...
 
   287..290.........300..
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Query Sequence  LLDAPFVRLQGNPLGE
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Template Conservation 
  
  
 
  

  
Template Sequence  FRNLTELDMRFNPFDC
Template Known Secondary structure  TT
S
TT



B
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   634.....640.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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