Return to main results Retrieve Phyre Job Id

Job DescriptionQ9ERV7
Confidence99.93%DateWed Jul 10 14:21:35 BST 2013
Rank12Aligned Residues253
% Identity31%Templatec2z64A_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 4; PDBTitle: crystal structure of mouse tlr4 and mouse md-2 complex
Resolution2.84 Å
Model Dimensions (Å)X:80.341 Y:73.109 Z:51.465

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   32.......40.........50.........60.........70.........80.........90.
Predicted Secondary structure 

































Query SS confidence 



























































Query Sequence  PGAPFLPAGNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVP
Query Conservation    

 
     
 
 
   
   
  
       
  

 
 

 
 
       
  
 
Alig confidence 



















...
































....
Template Conservation    

  
   
  
 

 
 ...
  
    
  
  
  
 

 
 
  
    
....
Template Sequence  SKVPDDIPSSTKNIDLSFNP. . . LKILKSYSFSNFSELQWLDLSRCEIETIEDKAW. . . .
Template Known Secondary structure  SS

SSS
SS



SS
...


TTTTSS
TT


SS




TTTT....
Template Predicted Secondary structure 














...






















....
Template SS confidence 



























































   45....50.........60.... .....70.........80.........90.......
 
   92.......100.........110.........120.........130.........140....... ..150
Predicted Secondary structure 










































.
Query SS confidence 























































.


Query Sequence  WSLLRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETLPT. CVP
Query Conservation    
  
  
 
  
 
         
 
  

  
  
  
  



 
 
  

 . 
 
Alig confidence 

















...........


























.


Template Conservation    
  
  
 

 
 
  ...........
    
  
  
  
 
  
 
  
      
Template Sequence  HGLHHLSNLILTGNPIQS. . . . . . . . . . . FSPGSFSGLTSLENLVAVETKLASLESFPIG
Template Known Secondary structure  TT
TT


TT




...........

TTTTTT
TT


TTS



TTT


T
Template Predicted Secondary structure 














...........


















Template SS confidence 



























































   98.100.........110..... ....120.........130.........140......
 
   151........160....... ..170.........180
Predicted Secondary structure 













..







............................
Query SS confidence 
















. .












. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  ELHGLDALLLSHNHLSE. . LPEALGALPALTF. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   
  
  
 
  
 
  ..

  
  
  
  ............................
Alig confidence 
















..












............................
Template Conservation   
  
  
 
  
                
  
    
                      
Template Sequence  QLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLS
Template Known Secondary structure  T
TT



SS







GGGGT
TT


TTS



TTTTTTTTT
TT


Template Predicted Secondary structure 























































Template SS confidence 



























































   147..150.........160.........170.........180.........190.........200......
 
  
Predicted Secondary structure  ............................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                              
Template Sequence  LDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDER
Template Known Secondary structure 
TT




TTTTTTS

SST
S

TTSS
Template Predicted Secondary structure 




















































Template SS confidence 



























































   207..210.........220.........230.........240.........250.........260......
 
  
Predicted Secondary structure  ............................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                           
                  
Template Sequence  NLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPK
Template Known Secondary structure 

S


GGGGTTTTTS


SS

TTGGG
GGGTT
SS









T
Template Predicted Secondary structure 



























































Template SS confidence 



























































   267..270.........280.........290.........300.........310.........320......
 
  
Predicted Secondary structure  ............................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                                   
          
Template Sequence  HFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFS
Template Known Secondary structure  T


SS


SS





TT

SBSS

B





TT



SBS
B
Template Predicted Secondary structure 



























































Template SS confidence 



























































   327..330.........340.........350.........360.........370.........380......
 
  
Predicted Secondary structure  ............................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ............................................................
Template Conservation                                     
                        
Template Sequence  GCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEK
Template Known Secondary structure 
SS
S




S
S
S

TT
TT


TTSSTTTS
TTTT
TT
Template Predicted Secondary structure 























































Template SS confidence 



























































   387..390.........400.........410.........420.........430.........440......
 
   181........ 190.........200.........210.. .......220.........230....
Predicted Secondary structure  ...






.















..















Query SS confidence  . . .








.






















. .





















Query Sequence  . . . LTVTHNRLE. RLPLTLGSLSTLQRLDLSENLLD. . TIPSEIGNLRSLSELNLASNRL
Query Conservation  ...
 
  
 
 . 

  
  
  
  
 

 
 
 .. 

  
  
  
  
 

 
 
Alig confidence  ...








.






















..





















Template Conservation 
                       
  
 
  
                
  
 

 
 
Template Sequence  LLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQL
Template Known Secondary structure 


TTS



S
TTTT
TT


TT
GGG
STTSS
TT
S
TT


Template Predicted Secondary structure 
























































Template SS confidence 



























































   447..450.........460.........470.........480.........490.........500......
 
   235....240 .........250.........260 .........270.........280....... .
Predicted Secondary structure 



.














.
















....
Query SS confidence 





.



















.


























. . . .
Query Sequence  QSLPAS. LAGLRSLRLLVLHSNLLTSV. PTGLVHLPLITRLDLRDNRLRDLPAEL. . . . L
Query Conservation    

  .
  
  
  
 
  
 
  
.
  
  
  
  



 
 
  

  
.... 
Alig confidence 





.



















.


























....
Template Conservation    
    
  
  
  
 

 
 
  
    
  
  
  
 

 
 
            
Template Sequence  EQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPK
Template Known Secondary structure 

TTTTTT
TT



SS


GGGTTT
TT



SS


S
GGGS
T
Template Predicted Secondary structure 








































Template SS confidence 



























































   507..510.........520.........530.........540.........550.........560......
 
   289290.........300..
Predicted Secondary structure 








Query SS confidence 













Query Sequence  DAPFVRLQGNPLGE
Query Conservation   
  
 
 



  
Alig confidence 













Template Conservation   
  
 
  
   
Template Sequence  SLAFFNLTNNSVAC
Template Known Secondary structure  T



S

B

Template Predicted Secondary structure 










Template SS confidence 













   567..570.........580
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D