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Job DescriptionQ62077
Confidence100.00%DateTue Jul 30 13:20:18 BST 2013
Rank2Aligned Residues744
% Identity34%Templatec3qr0A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21
Resolution2.00 Å
Model Dimensions (Å)X:72.902 Y:81.533 Z:72.311

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50.........60.........70.........80....
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Query Sequence  LCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPG
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Template Conservation 

  
  
    
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Template Sequence  VPEQLIKGDKFLKW. EEGSSGFIEILLRVDPKGYFLYWKIEGKEDTQLLDLAYVRDIRCA
Template Known Secondary structure 


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TT




TTS


TT
SS
GGGG
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   18.20.........30. ........40.........50.........60.........70......
 
   85....90 .........100.........110..... ....120.........130......
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Query Sequence  KTSRDF. . . . . . . DRYQEDPAFRPDQSHCFVILYGMEF. RLKTLSLQATSEDEVNMWIKG
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Template Sequence  KYAKPPKDKKIKEAGTNFGSSNIPLQDKCVTICHGYNYIDLEWTHLVAENSSVAKKWSEE
Template Known Secondary structure  GGS



SSS
TTS

SSSSS
SS
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   77..80.........90.........100.........110.........120.........130......
 
   137..140.........150.........160.........170.........180.. .......190.
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Query Sequence  LTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLS. . . . . QVNYRVPNM
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Template Conservation 
  
                               
  
 
 

          
     
Template Sequence  VFSYAYNLLSLNKNQLGEWEKLYFRLTTVEMEKNKIPVKAIQKCLSKDKDDRARISKALE
Template Known Secondary structure  T
T

TS

SS
S
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   137..140.........150.........160.........170.........180.........190......
 
   192.......200.........210.........220.........230.........240.........250.
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Query Sequence  RFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSL
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Template Conservation   
   
   
      
 
 

  
   
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Template Sequence  KIGWPSGKNDAIDLKAFDFDTFFKFYLAL. . LERSEIEGIFKE. . . . . . . LSKNKGNITT
Template Known Secondary structure  TS

STT
TTT

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T.......TTTSSS
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   197..200.........210.........220..... ....230....... ..240.......
 
   252.......260..... ....270.........280... ......290.........300...
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Query Sequence  SEFQQFLLEYQGEL. . . . . . . WAVDRLQVQEFMLSFLRD. PLREIEEPYFFLDELVTFLF
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Template Conservation       

   
      
 
           

   
            

 


   
 
Template Sequence  VMFRDFLNDMQRHPSLHKTLFPLYTDAQCEALINDYESAVNKKGKKKGQLTKEGLLYFLM
Template Known Secondary structure  TSS
TTS
TTTS



GGG
BTT
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   248.250.........260.........270.........280.........290.........300.......
 
   304.....310.........320.........330.........340.........350.........360...
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Query Sequence  SKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRC
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Template Sequence  CEENNLTPMHRLDLGAN. MKLTLAAYYINSSHNTYLTGHQLTGKSSVEIYRQVLLTGCRC
Template Known Secondary structure  SGGG
SS
SS
S
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S
GGG
BBSSTTBSS
TTTS
B
STT

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   308.310.........320.... .....330.........340.........350.........360......
 
   364.....370.........380.........390.........400.........410.........420...
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Query Sequence  IELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQR
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Template Sequence  LELDCWDGKDGEPIITHGFTMCTEVLFKDVVYAIAESAFKVSDYPVILSFENHCSVAQQK
Template Known Secondary structure 

TTSS


TTSS


TTSS

S



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   367..370.........380.........390.........400.........410.........420......
 
   424.....430.........440........ .450.........460.........470.........
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Query Sequence  NMAQHFRKVLGDTLLTKPVDIAADG. . . . LPSPNQLRRKILIKHKKLAEGSAYEEVPTSV
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Template Conservation    
       

 
   
           



  

 




 
               
Template Sequence  LLAQYCNEAFGELLLDKPIDGHPLKPGVPLPTPYDLRKKILIKNKKMHGLTDEEKKKIEK
Template Known Secondary structure  GGGB

S

TT

SSTT




TTTTTT








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   427..430.........440.........450.........460.........470.........480......
 
   480.........490.........500.........510.........520.........530.........
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Query Sequence  MYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEAS
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Template Conservation        ......................................................
Template Sequence  EKKDAG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  G......................................................
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   497..500..
 
   540.........550.........560.........570.........580.........590.........
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Query Sequence  SSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSF
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   600.........610.........620.........630.........640.........650.........
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Query Sequence  WRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQ
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   660.........670.........680.........690.........700.........710.........
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Query Sequence  TNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   720.........730.........740.........750.........760.........770.........
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Query Sequence  EGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRN
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   780.........790.........800.........810.........820.........830.........
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Query Sequence  PGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQL
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   840.........850.........860.........870.........880.........890.........
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Query Sequence  WFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSI
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
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   900.........910.........920.........930.........940.........950.........
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Query Sequence  SMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVY
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Template Conservation  ..........................................          


 

 
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TAAKEAEAAEEMSALVNY
Template Known Secondary structure  ..........................................GGGS




TT
SS
Template Predicted Secondary structure  ..........................................



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   503......510.........520
 
   960.........970.........980.........990.........1000.........1010.........
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Query Sequence  CRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLD
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Template Sequence  IQPVHFTTFEQAQKKDRHYEMSSMVETQALNKL. KDNPEDFVDYNKKQITRIYPKGTRVD
Template Known Secondary structure  S




T
TT.
TTTS


TT
TT
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   521........530.........540.........550... ......560.........570.........
 
   1020.........1030.........1040.........1050.........1060.........1070... ....
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Query Sequence  SSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEA. . FDPF
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Template Sequence  SSNYVPQIYWNAGCQLVALNFQCFDIAMCVNLGVFEYNGCSGYLLKPEFMRKLDKRFDPF
Template Known Secondary structure 




TTTT
S
B
TT

STTTTTT
S


TT



TT
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   580.........590.........600.........610.........620.........630.........
 
   1078.1080.........1090.........1100.........1110.........1120.... .....1130.....
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Query Sequence  DKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDST. . KQKTEFVVDNG
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Template Sequence  TESTVDGVVAGTIEIKIISAQFLSDKQ. . . ISSYVEVEMYGLPTDTVRKKFKTKIIENNG
Template Known Secondary structure 

S

TTS




SS
...

SSGGG



B
S
S
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   640.........650.........660...... ...670.........680.........690......
 
   1136...1140....... ..1150.........1160.........1170.........1180.........1190....
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Query Sequence  LNPVWPAKPFHF. QISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKN
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Template Sequence  MDPYYDEKVFVFKKVVLPDLAVVRIIVSEEN. . . . GKFIGHRVMPLDGIKPGYRHVPLRN
Template Known Secondary structure  S

B




S
GGG
TT....S
STT



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   697..700.........710.........720....... ..730.........740.........750..
 
   1195....1200.........1210.........1220.........1230.........1240...
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Query Sequence  NYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVR
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Template Conservation    
  
  




 
   
 
      
 
                   
Template Sequence  ESNRPLGLASVFAHIVAKDYVSYQSAQEARAAALCAFEDDPDAALNAAK
Template Known Secondary structure  TTS





SGGGGSSS
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   753......760.........770.........780.........790.........800.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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