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Job DescriptionQ62077
Confidence100.00%DateTue Jul 30 13:20:18 BST 2013
Rank3Aligned Residues673
% Identity36%Templatec2fjuB_
PDB info PDB header:signaling protein,apoptosis/hydrolaseChain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
Resolution2.20 Å
Model Dimensions (Å)X:87.567 Y:81.120 Z:59.287

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50.........60.........70.........80....
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Query Sequence  LCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPG
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Template Sequence  VKAYLSQGERFIKWDDETTVAS. PVILRVDPKGYYLYWTYQ. SKEMEFLDITSIRDTRFG
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SSSSS
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TTS
T.TS
GGGG
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   13......20.........30.... .....40.........50.. .......60.........70
 
   85....90.. .......100.........110..... ....120.........130.......
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Query Sequence  KTSRDFDR. . . . . . YQEDPAFRPDQSHCFVILYGMEF. RLKTLSLQATSEDEVNMWIKGL
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Template Sequence  KFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDV
Template Known Secondary structure  GGS



STTTTSTT

GGGT
SSSSS
SSSS
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   71........80.........90.........100.........110.........120.........130
 
   138.140.........150.........160. ........170.........180..... ....190...
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Query Sequence  TWLMEDTLQAATPLQIERWLRKQF. . YSVDRNREDRISAKDLKNMLSQVN. . YRVPNMRF
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Template Sequence  LALVKHPLTANASRS. . TFLDKILVKLKMQLNSEGKIPVKNFFQMFPADRKRVEAALSAC
Template Known Secondary structure  T
T

..S

TTS
STT
T
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   131........140..... ....150.........160.........170.........180........
 
   194.....200.........210.........220.........230.........240.........250...
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Query Sequence  LRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSLSE
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Template Sequence  HLPKGKNDAINPEDFPEPVYKSFLMSL. . CPRPEIDEIFTSY. . . . . . . . . . . . . MTKEH
Template Known Secondary structure  T


SSS

GGGS
TT..S



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B
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   189190.........200.........210..... ....220........ .230...
 
   254.....260.........270.........280.........290.........300.........310...
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Query Sequence  FQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQ
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Template Sequence  LTKFINQKQRDQ. . . . . . . . . GLIDKYEPS. . . . . . . GQLSPEGMVWFLCGPENSVLAQD
Template Known Secondary structure  TS


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B

STTS
SB
GG
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   241........250.. .......260. ........270.........280....
 
   314.....320.........330.........340.........350.........360.........370.
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Query Sequence  LDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDG. .
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Template Sequence  KLLLHHD. MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKP
Template Known Secondary structure  GGSS
S
.

S
GGG
BBSSTTBSS
SSSS
B
TTT




T
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   307..310... ......320.........330.........340.........350.........360.....
 
   372.......380.........390.........400.........410....... ..420.........430
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Query Sequence  PDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHC. SIAQQRNMAQHFR
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Template Sequence  PDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCR
Template Known Secondary structure  TTT



TTSS


TTTS

S




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   366...370.........380.........390.........400.........410.........420.....
 
   431........440.... .....450.........460.........470.........480......
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Query Sequence  KVLGDTLLTKPVDI. . . . AADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSVMYSENDI
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Template Sequence  TIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKEESGNLDEEEIKKMQSDEGT.
Template Known Secondary structure  GGGB

S

TTS
SSTT




TTTTTT










TTTTTTTTTTTGG.
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   426...430.........440.........450.........460.........470.........480....
 
   487..490.........500.........510.........520.........530.........540......
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Query Sequence  SNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTELHS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   547..550.........560.........570.........580.........590.........600......
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Query Sequence  SEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   607..610.........620.........630.........640.........650.........660......
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Query Sequence  HCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   667..670.........680.........690.........700.........710.........720......
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Query Sequence  EWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVML
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   727..730.........740.........750.........760.........770.........780......
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Query Sequence  GNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   787..790.........800.........810.........820.........830.........840......
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Query Sequence  NPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   847..850.........860.........870.........880.........890.........900......
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Query Sequence  EEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   907..910.........920.........930.........940.........950.........960......
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Query Sequence  WSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFD
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AGLEVTAYEEMSSLVNYIQPTKFV
Template Known Secondary structure  ....................................GG





TT
SS




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   532.......540.........550.....
 
   967..970.........980.........990.........1000.........1010.........1020......
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Query Sequence  EEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPL
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Template Sequence  SFEFSAQKNRSYVISSFTELKAYDLL. SKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQ
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T
TT.S

TT
TT





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   556...560.........570.........580. ........590.........600.........610....
 
   1027..1030.........1040.........1050.........1060.........1070.........1080......
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Query Sequence  PMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLE
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Template Sequence  MFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRR. . . . . . . . . . . . . . .
Template Known Secondary structure  TT


B
TT

STTTGGG
S

GGGT
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   615....620.........630.........640.........650.........
 
   1087..1090.........1100.........1110.........1120...... ...1130.........1140....
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Query Sequence  PCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQ. . KTEFVVDNGLNPVWPAKP
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Template Sequence  PTTLSITVISGQFLSERS. . . VRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEP
Template Known Secondary structure 

S

SS
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TTS







SSS

SS
B




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   660.........670....... ..680.........690.........700.........710......
 
   1145... .1150.........1160.........1170.........1180.........1190.........1200...
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Query Sequence  FHFQ. ISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELA
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Template Sequence  FVFEKILMPELASLRVAVMEEG. . . . NKFLGHRIIPINALNSGYHHLCLHSESNMPLTMP
Template Known Secondary structure 


S
GGG
TT....TGGGB


TT

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   734.....740.........750..... ....760.........770.........780.........
 
   1204.....1210...
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Query Sequence  SLLIKIDIFP
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Template Sequence  ALFIFLEMKD
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   790.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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