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Job DescriptionQ62077
Confidence100.00%DateTue Jul 30 13:20:18 BST 2013
Rank4Aligned Residues555
% Identity44%Templatec1djyB_
PDB info PDB header:lipid degradationChain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
Resolution2.80 Å
Model Dimensions (Å)X:86.857 Y:75.980 Z:57.452

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   170.........180.........190.........200.........210.........220.........
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Query Sequence  DRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMD
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Template Sequence  NKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKML. . TQRAEID
Template Known Secondary structure 



TT



T
SS
SS


..T

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   158.160.........170.........180.........190.........200........ .210.....
 
   230.........240.........250.........260.........270.........280.........
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Query Sequence  LPFLETNALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIE
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Template Sequence  RAFEE. . . . . . . AAGSAETLSVERLVTFLQHQQREE. EAGPALALSLIERY. EPSETAKA
Template Known Secondary structure  .......TTSSSTS

S.S
S.


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   216...220 .........230.........240.... .....250........ .260......
 
   290.........300.........310.........320.........330.........340.........
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Query Sequence  EPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESS
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Template Sequence  QRQMTKDGFLMYLLSADGNAFSLAHRRVYQD. MDQPLSHYLVSSSHNTYLLEDQLTGPSS
Template Known Secondary structure  TT
STTTBSB
GGGGS

S
.TTS
GGGSSTTBSS
SSS

B
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   267..270.........280.........290....... ..300.........310.........320.....
 
   350.........360.........370.........380.........390.........400.........
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Query Sequence  LEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPV
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Template Sequence  TEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPV
Template Known Secondary structure  TT



GGG



TTS



TTTS
SS
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   326...330.........340.........350.........360.........370.........380.....
 
   410.........420.........430.........440.........450.........460.........
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Query Sequence  ILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEG
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Template Sequence  ILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKL. . .
Template Known Secondary structure 

TTSB

S

SS

SS


TTTTTT



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   386...390.........400.........410.........420.........430.........440..
 
   470.........480.........490.........500.........510.........520.........
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Query Sequence  SAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGN
Query Conservation                         
              
  
     
    
       
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   530.........540.........550.........560.........570.........580.........
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Query Sequence  EDEEEPKEASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESE
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   590.........600.........610.........620.........630.........640.........
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Query Sequence  TFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEF
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   650.........660.........670.........680.........690.........700.........
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Query Sequence  EMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAE
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   710.........720.........730.........740.........750.........760.........
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Query Sequence  GKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEP
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   770.........780.........790.........800.........810.........820.........
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Query Sequence  DYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWW
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
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   830.........840.........850.........860.........870.........880.........
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Query Sequence  RGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEG
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Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   890.........900.........910.........920.........930.........940.........
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Query Sequence  KNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKI
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Template Conservation  ....................................................        
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GGLDKLKL
Template Known Secondary structure  ....................................................



TTT
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   443......450
 
   950.........960.........970. ........980.........990.........1000........
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Query Sequence  ALELSELVVYCRPVPFDEEKIG. TERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQL
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Template Sequence  VPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLL. QESGNGFVRHNVSCL
Template Known Secondary structure 
TT

S






SSS
S

TT.S
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   489490.........500.........510.........520.........530.. .......540.......
 
   10091010.........1020.........1030.........1040.........1050.........1060........
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Query Sequence  SRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPST
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Template Sequence  SRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAF
Template Known Secondary structure 

TT
TT




TTT


TTS
STTSGGG
S

GG
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   548.550.........560.........570.........580.........590.........600.......
 
   10691070... ......1080.........1090.........1100...... ...1110.........1120...
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Query Sequence  MRDEA. . FDPFDKSSLRGLEPCVICIEVLGARHLPKNGRG. . . IVCPFVEIEVAGAEYDS
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Template Sequence  LRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDT
Template Known Secondary structure  GS
TT



TTS

SSTT







S

SS



SSGGG
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   608.610.........620.........630.........640.........650.........660.......
 
   1124.....1130.........1140.........1150.........1160.........1170.........1180...
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Query Sequence  TKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGL
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Template Sequence  GSRQTAVITNNGFNPRWD. MEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSL
Template Known Secondary structure 



TT
SSS
.S
GGG


TTS

GGGB
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   668.670.........680..... ....690.........700.........710.........720......
 
   1184.....1190.........1200.........1210...
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Query Sequence  KTGYRAVPLKNNYSEDLELASLLIKIDIFP
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Template Sequence  KQGYRHVHLLSKNGDQHPSATLFVKISIQD
Template Known Secondary structure 


TTS

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   727..730.........740.........750......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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