Job Description Q62077 Confidence 99.94% Date Tue Jul 30 13:20:18 BST 2013 Rank 17 Aligned Residues 200 % Identity 26% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å Model Dimensions (Å) X:52.504 Y:59.614 Z:37.563

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		547	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	E	K	W	F	H	G	K	L	G	A	G	R	D	G	R	H	I	A	E	R	L	L	T	E	Y	C	I	E	T	G	A	P	D	G	S	F	L	V	R	E	S	E	T	F	V	G	D	Y	T	L	S	F	W	R	N	G	K	V	Q
Query Conservation
Alig confidence												.	.	.	.	.														.	.	.	.
Template Conservation												.	.	.	.	.														.	.	.	.
Template Sequence		H	L	P	F	F	F	G	N	I	T	.	.	.	.	.	R	E	E	A	E	D	Y	L	V	Q	G	G	M	.	.	.	.	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H
Template Known Secondary structure		G		T	T			S	S			.	.	.	.	.										T	T	T		.	.	.	.		T	T								S	S	S	T	T									S	S	S
Template Predicted Secondary structure												.	.	.	.	.														.	.	.	.
Template SS confidence
		12	.	.	.	.	.	.	.	20	.						.	.	.	.	.	.	.	.	30	.	.	.	.					.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.
		607	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Predicted Secondary structure																																																								.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.
Query Sequence		H	C	R	I	H	S	R	Q	D	A	G	T	P	K	F	F	L	T	D	N	L	V	F	D	S	L	Y	D	L	I	T	H	Y	Q	Q	V	P	L	R	C	N	E	F	E	M	R	L	S	E	P	V	P	Q	T	.	.	.	.	.	.
Query Conservation																																																								.	.	.	.	.	.
Alig confidence							.	.	.																																															.	.	.	.	.	.
Template Conservation							.	.	.
Template Sequence		H	Y	T	I	E	.	.	.	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q
Template Known Secondary structure							.	.	.			T	T	T					T	T	S			B	S	S									T	T			T	T	S	S	S				S	B					T	T
Template Predicted Secondary structure							.	.	.
Template SS confidence
		63	.	.	.	.				.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.
									661	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.		.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.
Predicted Secondary structure		.	.	.	.	.	.	.																								.
Query SS confidence		.	.	.	.	.	.	.																								.
Query Sequence		.	.	.	.	.	.	.	N	A	H	E	S	K	E	W	Y	H	A	S	L	T	R	A	Q	A	E	H	M	L	M	.	R	V	P	R	D	G	A	F	L	V	R	K	R	N	E	P	N	S	Y	A	I	S	F	R	A	E	G	K	I
Query Conservation		.	.	.	.	.	.	.																								.
Alig confidence		.	.	.	.	.	.	.																								.
Template Conservation
Template Sequence		L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V
Template Known Secondary structure									T	S	G	G	G		T	T																S	S				T	T								S	S	S	S									T	T
Template Predicted Secondary structure
Template SS confidence
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.
		713	.	.	.	.	.			.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.
Predicted Secondary structure								.	.
Query SS confidence								.	.
Query Sequence		K	H	C	R	V	Q	.	.	Q	E	G	Q	T	V	M	L	G	N	S	E	F	D	S	L	V	D	L	I	S	Y	Y	E	K	H	P	L	Y	R	K	M	K	L	R	Y	P	I	N	E
Query Conservation								.	.
Alig confidence								.	.
Template Conservation
Template Sequence		L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K
Template Known Secondary structure										T	T	S					T	T	S			B	S										T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		214	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D