Job Description A2A690 Confidence 98.97% Date Tue Jul 30 13:13:22 BST 2013 Rank 77 Aligned Residues 278 % Identity 18% Template c4kxfP_ PDB info PDB header:immune system Chain: P: PDB Molecule:nlr family card domain-containing protein 4; PDBTitle: crystal structure of nlrc4 reveals its autoinhibition mechanism Resolution 3.20 Å

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		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	I	V	G	N	I	G	F	G	K	T	A	I	I	S	R	L	V	A	L	S	C	H	G	T	R	M	R	Q	I	A	S	D	S	P	H	A	S	P	K	H	V	D	A	N	R	E	L	P	L	T	Q	A	P	S	A	H	S	S
Query Conservation
Alig confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		C	L	I	E	G	E	S	G	K	G	K	S	T	L	L	Q	R	I	A	M	L	W	A	S	G	G	C	R	A	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure							S	T	T	S	S																		S	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.
		426	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	T	S	G	S	C	P	G	T	P	E	M	R	R	R	Q	E	E	A	M	R	R	L	A	S	Q	V	V	A	Y	H	Y	C	Q	A	D	N	A	Y	T	C	L	V	P	E	F	V	H	N	V	A	A	L	L	C	R	S	P	Q	L
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.													.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.													.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	G	F	R	L	V	F	F	I	H	L	R	S	A	R	G	.	.	.	.	.	G	L	F	E	T	L	Y	D	Q	L	L	N	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G		S							G	G	G			S	.	.	.	.	.													.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.													.	.	.	.
Template SS confidence
																									195	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210						.	.	.	.	.	.	.	.	.	220	.	.
		486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	Y	R	E	Q	L	L	R	E	P	H	L	Q	S	M	L	S	L	R	S	C	V	Q	D	P	M	A	S	F	R	R	G	V	L	E	P	L	E	N	L	H	K	E	R	K	I	P	D	E	D	F	I	I	L	I	D	G	L	N
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	P	D	F	I	S	K	P	T	F	K	A	L	L	.	.	.	.	.	.	.	.	.	.	.	L	K	L	H	K	E	V	L	F	L	L	D	G	Y	N
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.			S	S											.	.	.	.	.	.	.	.	.	.	.				G	G	G								G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																						223	.	.	.	.	.	.	230	.	.	.	.	.	.												.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
		546	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	E	F	H	K	P	D	Y	G	D	T	I	V	S	F	L	S	K	M	I	G	N	F	P	S	W	L	K	L	I	V	T	V	R	T	S	L	Q	E	I	T	K	L	L	P	F	H	R	I	F	L	D	R	L	E	E	N	E	A
Query Conservation
Alig confidence				.	.	.														.	.							.																															.	.	.
Template Conservation				.	.	.														.	.							.																															.	.	.
Template Sequence		E	F	.	.	.	H	P	Q	N	C	P	E	I	E	A	L	I	K	.	.	E	N	H	R	F	K	.	N	M	V	I	V	T	T	T	T	E	C	L	R	H	I	R	H	V	G	A	L	T	A	E	V	G	D	M	T	E	.	.	.
Template Known Secondary structure		G		.	.	.		T	T	T										.	.			T	T	T		.									T	T	T					T	T	T		S											.	.	.
Template Predicted Secondary structure				.	.	.														.	.							.																															.	.	.
Template SS confidence
		252	.				.	.	.	.	.	.	260	.	.	.	.	.	.			.	.	.	270	.	.		.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
		606	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.		.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.
Predicted Secondary structure																																							.
Query SS confidence																																							.
Query Sequence		I	D	Q	D	L	Q	A	Y	I	L	H	R	I	H	S	S	S	E	I	Q	N	N	I	S	L	N	G	K	M	D	N	T	T	F	G	K	L	.	S	S	H	L	K	T	L	S	Q	G	S	Y	L	Y	L	K	L	T	F	D	L	I
Query Conservation																																							.
Alig confidence		.	.														.	.	.	.	.	.	.	.	.	.	.	.											.
Template Conservation		.	.														.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	D	S	A	K	D	L	I	E	A	V	L	V	P	.	.	.	.	.	.	.	.	.	.	.	.	D	Q	V	E	R	L	W	A	Q	I	Q	E	S	R	C	L	R	N	L	M	K	T	P	L	F	V	V	I	T	C	A	I	Q
Template Known Secondary structure		.	.											S			.	.	.	.	.	.	.	.	.	.	.	.																				T	T	S
Template Predicted Secondary structure		.	.														.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
				303	.	.	.	.	.	.	310	.	.	.	.	.													.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.
		665	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.									.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.	.
Query SS confidence																										.	.	.	.	.	.	.	.
Query Sequence		E	K	G	Y	L	V	L	K	S	S	S	Y	K	V	V	P	V	S	L	S	E	V	Y	L	.	.	.	.	.	.	.	.	L	Q	C	N	M	K	F	P	T	Q	S	S	F	D	R	V	M	P	L	L	N	V	A	V	A	S	L	H
Query Conservation																										.	.	.	.	.	.	.	.
Alig confidence						.	.	.	.	.	.	.	.													.	.	.	.	.	.	.	.																											.	.
Template Conservation						.	.	.	.	.	.	.	.																																															.	.
Template Sequence		M	G	R	Q	.	.	.	.	.	.	.	.	E	F	Q	A	H	T	Q	T	M	L	F	Q	T	F	Y	D	L	L	I	Q	K	N	S	H	R	Y	R	G	G	A	D	F	A	R	S	L	D	Y	C	G	D	L	A	L	E	G	.	.
Template Known Secondary structure				S	S	.	.	.	.	.	.	.	.	S				S	S																	G	G	G			T	T																		.	.
Template Predicted Secondary structure						.	.	.	.	.	.	.	.																																															.	.
Template SS confidence
		349	350	.	.									.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.
		717	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	L	T	D	E	H	I	F	Q	A	I	N	A	G	S	I	E	G	T	L	E	W	E	D	F	Q	Q	R	M	E	N	L	S	M	F	L	I	K	R	R	D	M	T	R	M	F	V	H	P	S	F	R	E	W	L	I	W	R
Query Conservation
Alig confidence		.	.	.	.	.
Template Conservation		.	.	.	.	.
Template Sequence		.	.	.	.	.	V	F	A	H	K	F	D	F	E	P	E	H	G	S	S	M	N	E	D	V	L	V	T	I	G	L	L	C	K	Y	T	A	Q	R	L	K	P	T	Y	K	F	F	H	K	S	F	Q	E	Y	T	A	G	R
Template Known Secondary structure		.	.	.	.	.				T				B				S	S	S											T	S	S					S			S	S						S	S
Template Predicted Secondary structure		.	.	.	.	.
Template SS confidence
							401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D